Infectious pulmonary complications in lung transplant recipients

Seminars in Respiratory Infections

Volumn 17, Issue 4, 2002, Pages 291-302

  Chan, Kevin M ^a   Allen, Samuel A ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMINOGLYCOSIDE; AMPHOTERICIN; ANTIBIOTIC AGENT; AZATHIOPRINE; CASPOFUNGIN; CEFTAZIDIME; CIPROFLOXACIN; CLINDAMYCIN; CORTICOSTEROID; CYCLOSPORIN; FLUCONAZOLE; FOSCARNET; GANCICLOVIR; HYPERIMMUNE GLOBULIN; ITRACONAZOLE; LYMPHOCYTE ANTIBODY; MACROLIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OSELTAMIVIR; PURINE DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RAPAMYCIN; RIBAVIRIN; TACROLIMUS; UNINDEXED DRUG; VALGANCICLOVIR; VANCOMYCIN; VORICONAZOLE; ZANAMIVIR;

ASPERGILLOSIS; ASPERGILLUS; BACTERIAL INFECTION; BRONCHIOLITIS; BRONCHOSCOPY; CANDIDA; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISEASE PREDISPOSITION; DONOR; EARLY DIAGNOSIS; GRAFT REJECTION; HISTOPATHOLOGY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LUNG FUNCTION; LUNG INFECTION; LUNG TRANSPLANTATION; MORBIDITY; NEPHROTOXICITY; NONHUMAN; PNEUMOCYSTIS CARINII; PNEUMONIA; PREVALENCE; PRIORITY JOURNAL; PROPHYLAXIS; RECIPIENT; REVIEW; RISK FACTOR; SIDE EFFECT; SURGICAL RISK; SYMPTOM; TREATMENT CONTRAINDICATION; TREATMENT OUTCOME; UPPER RESPIRATORY TRACT; WHEEZING;

HUMANS; LUNG DISEASES; LUNG TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; RESPIRATORY TRACT INFECTIONS; RISK FACTORS;

EID: 0036898489     PISSN: 08820546     EISSN: None     Source Type: Journal    
DOI: 10.1053/srin.2002.36444     Document Type: Review

References (83)

1. United Network for Organ Sharing: 2000 Annual Report of the U.S. Scientific Registry for Transplant Recipients and the Organ Procurement and Transplantation Network: Transplant data. Richmond, VA, United Network for Organ Sharing, 2000
2. Hosenpud JD, Bennett LE, Keck BM, et al: The registry of the International Society for Heart and Lung Transplantation: Eighteenth official report - 2001. J Heart Lung Transplant 20:805-815, 2001
3. Chan KM: Approach towards infectious pulmonary complications in lung transplant recipients, in Singh N, Aguado JM (eds): Infectious Complications in Transplant Patients. Norwell, MA, Kluwer Academic Publishers, 2001, pp 149-175
4. McAdams HP, Erasmus JJ, Palmer SM: Complications (excluding hyperinflation) involving the native lung after single-lung transplantation: Incidence, radiologic features, and clinical importance. Radiology 218:233-241, 2001
5. Metras D, Viard L, Kreitmann B, et al: Lung infections in pediatric lung transplantation: Experience in 49 cases. Eur J Cardiothorac Surg 15:490-495, 1999
6. Trulock EP: Lung transplantation. Am J Respir Crit Care Med 155:789-818, 1997
7. Halloran PF, Leung S: Approved immunosuppressants, in Norman EJ, Suki WN (eds): Primer on Transplantation. Thorofare, NJ, American Society of Transplant Physicians, 1998, pp 93-102
8. Snell GI, Levvey BJ, Chin W, et al: Rescue therapy: A role for sirolimus in lung and heart transplant recipients. Transplant Proc 33:1084-1085, 2001
9. Chaparro C, Kesten S: Infections in lung transplant recipients. Clin Chest Med 18:339-351, 1997
10. Aris RM, Gilligan PH, Neuringer IP, et al: The effects of panresistant bacteria in cystic fibrosis patients on lung transplant outcome. Am J Respir Crit Care Med 155:1699-1704, 1997
11. Flume PA, Egan TM, Paradowski LJ, et al: Infectious complications of lung transplantation. Impact of cystic fibrosis. Am J Respir Crit Care Med 149:1601-1607, 1994
12. Dauber JH, Paradis IL. Dummer JS: Infectious complications in pulmonary allograft recipients. Clin Chest Med 11: 291-308, 1990
13. Bando K, Paradis IL, Similo S, et al: Obliterative bronchiolitis after lung and heart-lung transplantation: An analysis of risk factors and management. J Thorac Cardiovasc Surg 110:4-14, 1995
14. Duncan SR, Paradis IL, Yousem SA, et al: Sequelae of cytomegalovirus pulmonary infections in lung allograft recipients. Am Rev Respir Dis 146:1419-1425, 1992
15. Smyth RL, Scott JP, Borysiewicz LK, et al: Cytomegalovirus infection in heart-lung transplant recipients: Risk factors, clinical associations, and response to treatment. J Infect Dis 164:1045-1050, 1991
16. Bailey TC, Trulock EP, Ettinger NA, et al: Failure of prophylactic ganciclovir to prevent cytomegalovirus disease in recipients of lung transplants. J Infect Dis 165:548-552, 1992
17. Ettinger NA, Bailey TC, Trulock EP. et al: Cytomegalovirus infection and pneumonitis. Impact after isolated lung transplantation. Washington University Lung Transplant Group. Am Rev Respir Dis 147:1017-1023, 1993
18. Hertz MI, Jordan C, Savik SK, et al: Randomized trial of daily versus three-times weekly prophylactic ganciclovir after lung and heart-lung transplantation. J Heart Lung Transplant 17:913-920, 1998
19. Chan KM, Veeraraghavan S, Barbers RG, et al: Effects of oral ganciclovir on the prevention of cytomegalovirus infection in lung transplant recipients. J Heart Lung Transplant 18: A209, 1999
20. Shreeniwas R, Schulman LL, Berkmen YM, et al: Opportunistic bronchopulmonary infections after lung transplantation: Clinical and radiographic findings. Radiology 200:349-356, 1996
21. Frist WH, Loyd JE, Merrill WH, et al: Single lung transplantation: A temporal look at rejection, infection, and survival. Am Surg 60:94-102, 1994
22. Cagle PT. Lega M: Pathogenesis/pathology of graft dysfunction, in Norman DJ, Suki WN (eds): Primer on Transplantation. Thorofare, NJ, American Society of Transplant Physicians, 1998, pp 527-537
23. Shelhammer JH, Toews GB, Masur H, et al: Respiratory disease in the immunosuppressed patient. Ann Intern Med 117: 415-431, 1992
24. Guilinger RA, Paradis IL, Dauber JH, et al: The importance of bronchoscopy with transbronchial biopsy and bronchoalveolar lavage in the management of lung transplant recipients. Am J Respir Crit Care Med 152:2037-2043, 1995
25. Scott JP, Fradet G, Smyth RL, et al: Prospective study of transbronchial biopsies in the management of heart-lung and single lung transplant patients. J Heart Lung Transplant 10:626-637, 1991
26. Trulock EP: Flexible bronchoscopy in lung transplantation. Clin Chest Med 20:77-87, 1999
27. Chan CC, Abi-Saleh WJ, Arroliga AC, et al: Diagnostic yield and therapeutic impact of flexible bronchoscopy in lung transplant patients. J Heart Lung Transplant 15:196-205, 1996
28. Higenbottam T, Stewart S, Penketh A, et al: Transbronchial lung biopsy for the diagnosis of rejection in heart-lung transplant patients. Transplantation 46:532-539, 1988
29. Yousem SA, Berry GJ, Cagle PT, et al: Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: Lung Rejection Study Group. J Heart Lung Transplant 15:1-15, 1996
30. Kahn FW, Jones JM: Diagnosing bacterial respiratory infection by bronchoalveolar lavage. J Infect Dis 155:862-869, 1987
31. Paradis IL, Grgurich WF, Dummer JS, et al: Rapid detection of cytomegalovirus pneumonia from lung lavage cells. Am Rev Respir Dis 138:697-702, 1988
32. Trulock EP, Ettinger NA, Brunt EM, et al: The role of transbronchial lung biopsy in the treatment of lung transplant recipients. An analysis of 200 consecutive procedures. Chest 102:1049-1054, 1992
33. Horvath J, Dummer S, Lloyd J, et al: Infection in the transplanted and native lung after single lung transplantation. Chest 104:681-685, 1993
34. Griffith BP, Hardesty RL, Armitage JM, et al: A decade of lung transplantation. Ann Surg 218:310-320, 1993
35. Maurer JR, Tullis E, Grossman RF, et al: Infectious complications following isolated lung transplantation. Chest 101: 1056-1059, 1992
36. Chow JW, Yu VL: Legionella: A major opportunistic pathogen in transplant recipients. Semin Respir Infect 13:132-139, 1998
37. Hebart H, Kanz L, Jahn G, et al: Management of cytomegalovirus infection after solid-organ or stem-cell transplantation: Current guidelines and future prospects. Drugs 55: 59-72, 1998
38. Egan JJ, Lomax J, Barber L, et al: Preemptive treatment for the prevention of cytomegalovirus disease in lung and heart transplant recipients. Transplantation 65:747-752, 1998
39. Sanchez JL, Kruger RM, Paranjothi S, et al: Relationship of cytomegalovirus viral load in blood to pneumonitis in lung transplant recipients. Transplantation 72:733-735, 2001
40. Michaelides A, Liolios L, Glare EM, et al: Increased human cytomegalovirus (HCMV) DNA load in peripheral blood leukocytes after lung transplantation correlates with HCMV pneumonitis. Transplantation 72:141-147, 2001
41. Bhorade SM, Sandesara C, Garrity ER, et al: Quantification of cytomegalovirus (CMV) viral load by the hybrid capture assay allows for early detection of CMV disease in lung transplant recipients. J Heart Lung Transplant 20:928-934, 2001
42. Duncan SR, Grgurich WF, Iacono AT, et al: A comparison of ganciclovir and acyclovir to prevent cytomegalovirus after lung transplantation. Am J Respir Crit Care Med 150:146-152, 1994
43. Asmi AE, Chan KM, Nguyen PT, et al: Efficacy of IV ganciclovir followed by oral therapy for the prevention of CMV infection in lung transplant recipients. Am J Respir Crit Care Med 159:A738, 1999
44. Curran M, Noble S: Valganciclovir. Drugs 61:1145-1150, 2001
45. Pescovitz MD, Rabkin J, Merion RM, et al: Valganciclovir results in improved oral absorption of ganciclovir in liver transplant recipients. Antimicrob Agents Chemother 44:2811-2815, 2000
46. Limaye AP, Raghu G, Koelle DM, et al: High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy. J Infect Dis 185:20-27, 2002
47. Gerbase MW, Dubois D, Rothmeier C, et al: Costs and outcomes of prolonged cytomegalovirus prophylaxis to cover the enhanced immunosuppression phase following lung transplantation [see comments]. Chest 116:1265-1272, 1999
48. Zamora MR, Fullerton DA, Campbell DN, et al: Use of cytomegalovirus (CMV) hyperimmune globulin for prevention of CMV disease in CMV-seropositive lung transplant recipients. Transplant Proc 26:49-51, 1994 (suppl 1)
49. Maurer JR, Snell G, deHoyos A, et al: Outcomes of lung transplantation using three different cytomegalovirus prophylactic regimens. Transplant Proc 25:1434-1435, 1993
50. Holt ND, Gould FK, Taylor CE, et al: Incidence and significance of noncytomegalovirus viral respiratory infection after adult lung transplantation. J Heart Lung Transplant 16:416-419, 1997
51. Palmer SM, Henshaw NG, Howell DN, et al: Community respiratory viral infection in adult lung transplant recipients. Chest 113:944-950, 1998
52. Wendt CH, Fox JML, Hertz MI: Paramyxovirus infection in lung transplant recipients. J Heart Lung Transplant 14:479-485, 1995
53. Matar LD, McAdams HP, Palmer SM, et al: Respiratory viral infections in lung transplant recipients: Radiologic findings with clinical correlation. Radiology 213:735-742, 1999
54. Myerowitz RL, Stalder H, Oxman MN, et al: Fatal disseminated adenovirus infection in a renal transplant recipient. Am J Med 59:591-598, 1975
55. Krinzman S, Basgoz N, Kradin R, et al: Respiratory syncytial virus-associated infections in adult recipients of solid organ transplants. J Heart Lung Transplant 17:202-210, 1998
56. Sleiman CH, Roue C, Mal H, et al: Respiratory syncytial virus (RSV) infection in single lung transplant recipients. Am J Respir Crit Care Med 153:A263, 1996 (abstr)
57. Simsir A, Greenebaum E, Nuovo G, et al: Late fatal adenovirus pneumonitis in a lung transplant recipient. Transplantation 65:592-594, 1998
58. Hodges TN, Torres FP, Zamora MR: Treatment of respiratory syncytial viral and parainfluenza lower respiratory tract infection in lung transplant patients. J Heart Lung Transplant 20:170, 2001
59. Paya CV: Fungal infections in solid-organ transplantation. Clin Infect Dis 16:677-688, 1993
60. Paradowski LJ: Saprophytic fungal infections and lung transplantation-revisited. J Heart Lung Transplant 16:524-531, 1997
61. Westney GE, Kesten S, De Hoyos A, et al: Aspergillus infection in single and double lung transplant recipients. Transplantation 61:915-919, 1996
62. Kramer MR, Denning DW, Marshall SE, et al: Ulcerative tracheobronchitis after lung transplantation: A new form of invasive aspergillosis. Am Rev Respir Dis 144:552-556, 1991
63. Hamacher J, Spiliopoulos A, Kurt AM, et al: Preemptive therapy with azoles in lung transplant patients. Geneva Lung Transplantation Group. Eur Respir J 13:180-186, 1999
64. Mehrad B, Paciocco G, Martinez FJ, et al: Spectrum of Aspergillus infection in lung transplant recipients: Case series and review of the literature. Chest 119:169-175, 2001
65. Monforte V, Roman A, Gavalda J, et al: Nebulized amphotericin B prophylaxis for Aspergillus infection in lung transplantation: Study of risk factors. J Heart Lung Transplant 20: 1274-1281, 2001
66. Kessler R, Massard G, Warter A, et al: Bronchialpulmonary artery fistula after unilateral lung transplantation: A case report [see comments]. J Heart Lung Transplant 16:674-677, 1997
67. Egan JJ, Yonan N, Carroll KB, et al: Allergic bronchopulmonary aspergillosis in lung allograft recipients. Eur Respir J 9:169-171, 1996
68. Fitzsimons EJ, Aris R, Patterson R: Recurrence of allergic bronchopulmonary aspergillosis in the posttransplant lungs of a cystic fibrosis patient. Chest 112:281-282, 1997
69. Diederich S, Scadeng M, Dennis C, et al: Aspergillus infection of the respiratory tract after lung transplantation: Chest radiographic and CT findings. Eur Radiol 8:306-312, 1998
70. Fisher JH: Infectious complications of lung transplantation. Semin Respir Crit Care Med 17:167-171, 1996
71. Linden P, Williams P, Chan KM: Efficacy and safety of amphotericin B lipid complex injection (ABLC) in solid-organ transplant recipients with invasive fungal infections. Clin Transplant 14:329-339, 2000
72. Denning DW, Ribaud P, Milpied N, et al: Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis. Clin Infect Dis 34:563-571, 2002
73. Walsh TJ, Pappas P, Winston DJ, et al: Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever. N Engl J Med 346:225-234, 2002
74. Keating GM, Jarvis B: Caspofungin. Drugs 61:1121-1129, 2001
75. Kesten S, Chaparro C: Mycobacterial infections in lung transplant recipients. Chest 115:741-745, 1999
76. Schulman LL, Scully B, McGregor CC, et al: Pulmonary tuberculosis after lung transplantation. Chest 111:1459-1462, 1997
77. Malouf MA, Glanville AR: The spectrum of mycobacterial infection after lung transplantation. Am J Respir Crit Care Med 160:1611-1616, 1999
78. Carlsen SE, Bergin CJ: Reactivation of tuberculosis in a donor lung after transplantation. AJR Am J Roentgenol 154:495-407, 1990
79. Dromer C, Nashef SA, Velly JF, et al: Tuberculosis in transplanted lungs. J Heart Lung Transplant 12:924-927, 1993
80. Chusid MJ, Splaingard ML, Tweddell JS, et al: Pulmonary tuberculosis after lung-liver transplantation for cystic fibrosis. Pediatr Infect Dis J 15:462-464, 1996
81. Ridgeway AL, Warner GS, Phillips P, et al: Transmission of Mycobacterium tuberculosis to recipients of single lung transplants from the same donor. Am J Respir Crit Care Med 153: 1166-1168, 1996
82. Miller RA, Lanza LA, Kline JN, et al: Mycobacterium tuberculosis in lung transplant recipients. Am J Respir Crit Care Med 152:374-376, 1995
83. Kramer MR, Stoehr C, Lewiston NJ, et al: Trimethoprim-sulfamethoxazole prophylaxis for Pneumocystis carinii infections in heart-lung and lung transplantation - How effective and for how long? Transplantation 53:586-589, 1992