Discontinuation of immunosuppression for prevention of kidney graft rejection after receiving a bone marrow transplant from the same HLA identical sibling donor

American Journal of Hematology

Volumn 71, Issue 4, 2002, Pages 311-313

  Gajewski, James L ^a   Ippoliti, Cindy ^a   Ma, Yan ^a   Champlin, Richard ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Bone marrow transplant; Kidney transplant; Tolerance

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; DAUNORUBICIN; HLA ANTIGEN; METHOTREXATE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ACUTE LEUKEMIA; ADULT; ANEMIA; ARTICLE; BONE MARROW TRANSPLANTATION; CASE REPORT; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; ORGAN DONOR; PANCYTOPENIA; PRIORITY JOURNAL; SIBLING; THROMBOCYTOPENIA;

BONE MARROW TRANSPLANTATION; FEMALE; GRAFT REJECTION; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MIDDLE AGED; SIBLINGS;

EID: 0036893468     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajh.10206     Document Type: Article

References (19)

1. Schlitt HJ, Raddatz G, Steinhoff G, Wonigeit K, Pichlmayr R. Passenger lymphocytes in human liver allografts and their potential role after transplantation. Transplantation 1993;56:1001-1007.
2. Kahan BD. Role of cyclosporin: Present and future. Transplant Proc 1994;26:3082-3087.
3. Richter N, Raddatz G, Graeter T, Schafers HJ, Schlitt HJ. Allogeneic lymphocyte chimerism after clinical lung transplantation. Transplant Immunol 1995;3:74-80.
4. Shi Q, Wu MH, Fujita Y, Ishida A, Wijelath ES, Hammond WP, Wechezak AR, Yu C, Storb RF, Sauvage LR. Genetic tracing of arterial graft flow surface endothelialization in allogeneic marrow transplanted dogs. Cardiovasc Surg 1999;7:98-105.
5. Billingham RE, Brent L, Medawar PB. Actively acquired tolerance of foreign cells. Nature 1953;172:603-606.
6. Barber WH, Mankin JA, Laskow DA, Deierhoi MH, Julian BA, Curtis JJ, Diethelm AG. Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients. Transplantation 1991;51:70-75.
7. Dey B, Sykes M, Spitzer T. Outcomes of recipients of both bone marrow and solid organ transplants: A review. Medicine 1998;77:355-369.
8. Kawai T, Cosimi AB, Colvin RB, Powelson J, Eason J, Kozlowski T, Sykes M, Monroy R, Tanaka M, Sachs DH. Mixed allogeneic chimerism and renal allograft tolerance in cynomologous monkeys. Transplantation 1995;59:256-262.
9. Ricordi C, Karatzas T, Nery J, Webb M, Selvaggi G, Fernandez L, Khan FA, Ruiz P, Schiff E, Olson L, Fernandez H, Bean J, Esquenazi V, Miller J, Tzakis AG. High-dose bone marrow infusions to enhance allograft survival: The effect of timing. Transplantation 1997;63:7-11.
10. Sorof JM, Koerper MA, DeSantes K, Cowan M. Renal transplantation without chronic immunosuppression after T-cell depleted, HLA-mismatched bone marrow transplantation. Transplantation 1995;59:1633-1635.
11. Spitzer TR, Zwiebel J, Jacobson RJ. Transplants from the same donor. Ann Intern Med 1991;115:498.
12. Sykes M, Szot GL, Swenson KA, Pearson DA. Induction of high levels of allogeneic hematopoietic reconstitution and donor specific tolerance without myelosuppressive conditioning. Nat Med 1997;3:783-787.
13. Vesole DH, Jagannath S. Transplants from the same donor. Ann Intern Med 1992;116:269-270.
14. Helg C, Chapuis B, Bolle JF, Morel P, Salomon D, Roux E, Antonioli V, Jeannet M, Leski M. Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic BMT. Transplantation 1994;58:1420-1422.
15. Hill RS, Petersen FB, Storb R, Appelbaum FR, Doney K, Dahlberg S, Ramberg R, Thomas ED. Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease. Blood 1986;67:811-816.
16. Carella AM, Giralt S, Slavin S. Low intensity regimens with allogeneic hematopoietic stem cell transplantation treatment of hematologic neoplasia. Haemtologica 2000;85:304-313.
17. Tomita Y, Khan A, Sykes M. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with non-myeloablative regimen. J Immunol 1994;153:1087-1098.
18. Svendsen U, Aggrestrup S, Heilmann C, Jacobsen N, Svejgaard A, Thistad B. Transplantation of a lobe of lung from mother to child following previous transplantation with maternal bone marrow. Transplant Proc 1995;27:3483-3484.
19. Sayegh MH, Fine NA, Milford EL, Tilney NL. Immunologic tolerance to renal allografts after bone marrow transplants from same donors. Ann Intern Med 1991;114:954-955.