Analysis of Ebh, a 1.1-Megadalton cell wall-associated fibronectin-binding protein of Staphylococcus aureus

Infection and Immunity

Volumn 70, Issue 12, 2002, Pages 6680-6687

  Clarke, Simon R ^a   Harris, Llinos G ^a,b   Richards, R Geoff ^b   Foster, Simon J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b AO RESEARCH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; FIBRONECTIN; MEMBRANE PROTEIN; PROTEIN EBH; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL WALL; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

ABSCESS; ADHESINS, BACTERIAL; ANIMALS; BACTERIAL PROTEINS; CARRIER PROTEINS; CELL WALL; DISEASE MODELS, ANIMAL; FIBRONECTINS; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MICE; MUTATION; SEQUENCE ANALYSIS, DNA; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION, GENETIC; VIRULENCE;

EID: 0036893408     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.12.6680-6687.2002     Document Type: Article

References (58)

1. Ahmed, S., S. Meghji, R. J. Williams, B. Henderson, J. H. Brock, and S. P. Nair. 2001. Staphylococcus aureus fibronectin-binding proteins are essential for internalization of osteoblasts but do not account for differences in intracellular levels of bacteria. Infect. Immun. 69:2872-2877.
2. Allignet, J., S. Aubert, K. G. H. Dyke, and N. El Solh. 2001. Staphylococcus caprae strains carry determinants known to be involved in pathogenicity: A gene encoding an autolysin-binding fibronectin and the ica operon involved in biofilm formation. Infect. Immun. 69:712-718.
3. Braun, L., S. Dramsi, P. Dehoux, H. Bierne, G. Lindahl, and P. Cossart. 2001. InlB: And invasion protein of Listeria monocytogenes with a novel type of surface association. Mol. Microbiol. 25:285-294.
4. Chan, P. F., and S. J. Foster. 1998. The role of environmental factors in the regulation of virulence determinant expression in Staphylococcus aureus 8325-4. Microbiology 144:2469-2479.
5. Chan, P. F., and S. J. Foster. 1998. Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus. J. Bacteriol. 180:6232-6241.
6. Chan, P. F., S. J. Foster, E. Ingham, and M. O. Clements. 1998. The Staphylococcus aureus alternative sigma factor σB controls the environmental stress response but not starvation survival or pathogenicity in a mouse abscess model. J. Bacteriol. 180:6082-6089.
7. Chattwal, G. S., and K. T. Preissner. 2000. Extracellular matrix interactions with gram-positive pathogens, p. 78-86. In V. A. Fischetti (ed.), Gram-positive Pathogens. American Society for Microbiology. Washington, D.C.
8. Downer, R., F. Roche, P. W. Park, R. P. Mecham, and T. J. Foster. 2002. The elastin binding protein of Staphylococcus aureus (EbpS) is expressed at the cell surface as an integral membrane protein and not as a cell wall-associated protein. J. Biol. Chem. 277:243-250.
9. Dziewanowska, K., J. M. Patti, C. F. Deobald, K. W. Bayles, W. R. Trible, and G. A. Bohach. 1999. Fibronectin binding protein and host cell tyrosine kinase are required for internalization of Staphylococcus aureus by epithelial cells. Infect. Immun. 67:4673-4678.
10. Etz, H., D. B. Minh, T. Henics, A. Dryla, B. Winkler, C. Triska, A. P. Boyd, J. Söllner, W. Schmidt, U. von Ahsen, M. Buschle, S. R. Gill, J. Kolonay, H. Khalak, C. M. Fraser, A. von Gabain, E. Nagy, and A. Meinke. 2002. Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus. Proc. Natl. Acad. Sci. USA 99:6573-6578.
11. Flock. J., S. A. Hienz, A. Heimdahl, and T. Schennings. 1996. Reconsideration of the role of fibronectin binding in endocarditis caused by Staphylococcus aureus. Infect. Immun. 64:1876-1878.
12. Foster, S. J. 1993. Molecular analysis of three major wall-associated proteins of Bacillus subtilis 168: Evidence for processing of the product of a gene encoding a 258-kDa precursor two-domain ligand-binding protein. Mol. Microbiol. 8:299-310.
13. Foster, T. J., and M. Höök. 1998. Surface protein adhesins of Staphylococcus aureus. Trends Microbiol. 6:484-488.
14. B activity depends on RsbU in Staphylococcus aureus. J. Bacteriol. 183:1843-1852.
15. Greene, C., D. McDevitt, P. Francois, P. E. Vaudaux, D. P. Lew, and T. J. Foster. 1995. Adhesion properties of mutants of Staphylococcus aureus defective in fibronectin-binding proteins and studies on the expression offnb genes. Mol. Microbiol. 17:1143-1152.
16. Hartleib, J., N. Köhler, R. B. Dickinson, G. S. Chattwal, J. J. Sixma, O. M. Hartford, T. J. Foster, G. Peters, B. E. Kehrel, and M. Herrmann. 2000. Protein A is the von Willebrand factor binding protein on Staphylococcus aureus. Blood 96:2149-2156.
17. Hell, W., H. W. Meyer, and S. G. Gatermann. 1998. Cloning of aas, a gene encoding a Staphylococcus saprophyticus surface protein with adhesive and autolytic properties. Mol. Microbiol. 29:871-881.
18. Herrmann, M., S. J. Suchard, L. A. Boxer, F. A. Waldvogel, and P. D. Lew. 1991. Thrombospondin binds Staphylococcus aureus and promotes staphylococcal adherence to surfaces. Infect. Immun. 59:279-288.
19. Holtje, J. V., and A. Tomasz. 1975. Specific recognition of choline residues in the cell wall teichoic acid by the N-acetylmuramyl-L-alanine amidase of pneumococcus. J. Biol. Chem. 250:6072-6076.
20. House-Pompeo, K., Y. Xu, D. Joh, P. Speziale, and M. Höök. 1996. Conformational changes in the fibronectin-binding MSCRAMMs are induced by ligand binding. J. Biol. Chem. 271:1379-1384.
21. Hussain, M., K. Becker, C. von Eiff, J. Schrenzel, G. Peters, and M. Herrmann. 2001. Identification and characterization of a novel 38.5-kilodalton cell surface protein of Staphylococcus aureus with extended-spectrum binding activity for extracellular matrix and plasma proteins. J. Bacteriol. 183:6778-6786.
22. Ji, G., R. C. Beavis, and R. P. Novick. 1995. Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc. Natl. Acad. Sci. USA 92:12055-12059.
23. Joh, D., E. R. Wann, B. Kreikemeyer, P. Speziale, and M. Höök. 1999. Role of fibronectin-binding MSCRAMMs in bacterial adherence and entry into mammalian cells. Matrix Biol. 18:211-223.
24. Jonquieres, R., H. Bierne, F. Fiedler, P. Gounon, and P. Cossart. 1999. Interaction between the protein InlB of Listeria monocytogenes and lipoteichoic acid: A novel mechanism of protein association at the surface of gram-positive bacteria. Mol. Microbiol. 34:902-914.
25. Jönsson, K., C. Signäs, H. Mfiller, and M. Lindberg. 1991. Two different genes encode fibronectin-binding proteins in Staphylococcus aureus. Eur. J. Biochem. 202:1041-1048.
26. Josefsson, E., O. Hartford, L. O'Brien, J. M. Patti, and T. Foster. 2001. Protection against experimental Staphylococcus aureus arthritis by vaccination with clumping factor A, a novel virulence determinant. J. Infect. Dis. 184:1572-1580.
27. Kemp, E. H., R. L. Sammons, A. Moir, D. Sun, and P. Setlow. 1991. Analysis of transcriptional control of the gerD spore germination gene of Bacillus subtilis 168. J. Bacteriol. 173:4646-4652.
28. Komatsuzawa, H., K. Ohta, M. Sugai, T. Fujiwara, P. Glanzmann, B. Berger-Bachi, and H. Suginaka. 2000. Tn551-mediated insertional inactivation of the fmtB gene encoding a cell wall-associated protein abolishes methicillin resistance in Staphylococcus aureus. J. Antimicrob. Chemother. 45:421-431.
29. Kornblum, J., B. J. Hartmann, R. P. Novick, and A. Tomasz. 1986. Conversion of a homogeneously methicillin-resistant strain of Staphylococcus aureus to heterogeneous resistance by Tn551-mediated insertional inactivation. Eur. J. Clin. Microbiol. 5:714-718.
30. Kreiswirth, B., S. Löfdahl, M. J. Betley, M. O'Reilly, P. Schleivert, M. S. Bergdoll, and R. P. Novick. 1983. The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305:709-712.
31. Kuroda, M., T. Ohta, I. Uchiyama, T. Baba, H. Yuzawa, I. Kobayashi, L. Cui, A. Oguchi, K. Aoki, Y. Nagai, J. Lian, T. Ito, M. Kanamori, H. Matsumaru, A. Maruyama, H. Murakami, A. Hosoyama, Y. Mizutani-Ui, N. K. Takahashi, T. Sawano, R. Inoue, C. Kaito, K. Sekimizu, H. Hirakawa, S. Kuhara, S. Goto, J. Yabuzaki, M. Kanehisa, A. Yamashita, K. Oshima, K. Furuya, C. Yoshino, T. Shiba, M. Hattori, N. Ogasawara, H. Hayashi, and K. Hiramatsu. 2001. Whole genome sequencing of methicillin-resistant Staphylococcus aureus. Lancet 357:1225-1240.
32. Lindsay, J. A., and S. J. Foster. 1999. Interactive regulatory pathways control virulence determinant production and stability in response to environmental conditions in Staphylococcus aureus. Mol. Gen. Genet. 262:323-331.
33. Manganelli, R., and I. van de Rijn. 1999. Characterization of emb, a gene encoding the major adhesin of Streptococcus defectivus. Infect. Immun. 67:50-56.
34. Massey, R. C., M. N. Kantzanou, T. Fowler, N. P. J. Day, K. Schofield, E. R. Wann, A. R. Berendt, M. Höök. and S. J. Peacock. 2001. Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells. Cell. Microbiol. 3:839-851.
35. Mazmanian, S. K., H. Ton-That, and O. Schneewind. 2001. Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus. Mol. Microbiol. 40:1049-1057.
36. McDevitt, D., P. François, P. Vaudaux, and T. J. Foster. 1994. Molecular characterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus. Mol. Microbiol. 11:237-248.
37. Miyamoto, Y. J., E. R. Wann, T. Fowler, E. Duffield, M. Höök. and B. W. McIntyre. 2001. Fibronectin binding protein A of Staphylococcus aureus can mediate human T lymphocyte adhesion and coactivation. J. Immunol. 166:5129-5138.
38. Mongodin, E., O. Bajolet, J. Cutrona, N. Bonnet, F. Dupuit, E. Puchelle, and S. de Bentzmann. 2002. Fibronectin-binding proteins of Staphylococcus aureus are involved in adherence to human airway epithelium. Infect. Immun. 70:620-630.
39. Moreillon, P., J. M. Entenza, P. Francioli, D. McDevitt, T. J. Foster, P. François, and P. Vaudaux. 1995. Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis. Infect. Immun. 63:4738-4743.
40. Ni Eidhin, D., S. Perkins, P. François, P. Vaudaux, M. Höök. and T. J. Foster. 1998. Clumping factor B (ClfB), a new surface-located fibrinogen-binding adhesin of Staphylococcus aureus. Mol. Microbiol. 30:245-257.
41. Novick, R. 1967. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology 33:155-166.
42. Palma, M., A. Haggar, and J. Flock. 1999. Adherence of Staphylococcus aureus is enhanced by an endogenous secreted protein with broad binding activity. J. Bacteriol. 181:2840-2845.
43. Peacock, S. J., T. J. Foster, B. J. Cameron, and A. R. Berendt. 1999. Bacterial fibronectin-binding proteins and endothelial cell surface fibronectin mediate adherence of Staphylococcus aureus to resting human endothelial cells. Microbiology 145:3477-3486.
44. Que, Y., P. François, J. Haefliger, J. Entenza, P. Vaudaux, and P. Moreillon. 2001. Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis. Infect. Immun. 69:6296-6302.
45. Saravia-Otten, P., H. Müller, and S. Arvidson. 1997. Transcription of Staphylococcus aureus fibronectin-binding protein genes is negatively regulated by agr and an agr-independent mechanism. J. Bacteriol. 197:5259-5263.
46. Schenk, S., and R. A. Laddaga. 1992. Improved methods for electroporation of Staphylococcus aureus. FEMS Microbiol. Lett. 94:133-138.
47. 1. Cell. Microbiol. 1:101-117.
48. Sinha, B., P. P. François, Y. Que, M. Hussain, C. Heilmann, P. Moreillon, D. Lew, K. Krause, G. Peters, and M. Herrmann. 2000. Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infect. Immun. 68:6871-6878.
49. Stutzmann-Meier, P., J. M. Entenzak, P. Vaudaux, P. Francioli, M. P. Glauser, and P. Moreillon. 2001. Study of Staphylococcus aureus pathogenic genes by transfer and expression in the less virulent organism Streptococcus gordonii. Infect. Immun. 69:657-664.
50. Switalski, L. M., J. M. Patti, W. Butcher, A. G. Gristina, P. Speziale, and M. Höök. 1993. A collagen receptor on Staphylococcus aureus strains isolated from patients with septic arthritis mediates adhesion to cartilage. Mol. Microbiol. 7:99-107.
51. Tung, S., B. Guss, U. Hellman, L. Persson, K. Rubin, and C. Ryden. 2000. A bone sialoprotein-binding protein from Staphylococcus aureus: A member of the staphylococcal Sdr family. Biochem. J. 345:611-619.
52. Vagner, V., E. Dervyn, and S. D. Erlich. 1998. A vector for systematic gene inactivation in Bacillus subtilis. Microbiology 144:3097-3104.
53. van Wely, K. H. M., J. Swaving, R. Freudl, A. J. M. Driessen. 2001. Translocation of proteins across the cell envelope of gram-positive bacteria. FEMS Microbiol. Rev. 25:437-454.
54. Visai, L., Y. Xu, F. Casolini, S. Rindi, M. Höök. and P. Speziale. 2000. Monoclonal antibodies to CNA, a collagen-binding microbial surface component recognizing adhesive matrix molecules, detach Staphylococcus aureus from a collagen substrate. J. Biol. Chem. 275:39837-39845.
55. Waldvogel, F. A. 1995. Staphylococcus aureus (including toxic shock syndrome), p. 1754-1777. In G. L. Mandell, J. E. Bennett, and R. Dolio (ed.), Principles and Practice of Infectious Diseases. Churchill Livingstone, New York, N.Y.
56. Wann, E. R., S. Gurusiddappa, and M. Höök. 2000. The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus is a bifunctional protein that also binds fibrinogen. J. Biol. Chem. 275:13863-13871.
57. Wu, S. W., and H. De Lencastre. 1999. Mrp: A new auxiliary gene essential for optimal expression of methicillin resistance in Staphylococcus aureus. Microb. Drug Resist. 5:9-18.
58. B. Proteomics 1:480-493.