Time course of quartz and TiO2 particle-induced pulmonary inflammation and neutrophil apoptotic responses in rats

Experimental Lung Research

Volumn 28, Issue 8, 2002, Pages 641-670

  Zhang, Donna D ^a   Hartsky, Mark A ^a   Warheit, David B ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Apoptosis; Lung inflammation; Neutrophil apoptosis; Quartz particles; Resolution of inflammation; Silica particles; Titanium dioxide particles

Indexed keywords

SILICON DIOXIDE; TITANIUM DIOXIDE; BIOMATERIAL; DNA FRAGMENT; TITANIUM;

AIRBORNE PARTICLE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG TOXICITY; NEUTROPHIL; NICK END LABELING; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RAT; SILICOSIS; TIME; ANIMAL; CYTOLOGY; DRUG EFFECT; GERMFREE ANIMAL; IMMUNOLOGY; MALE; PATHOLOGY; RAT STRAIN; REACTION TIME;

ANIMALS; BIOCOMPATIBLE MATERIALS; BRONCHOALVEOLAR LAVAGE FLUID; DNA FRAGMENTATION; IN SITU NICK-END LABELING; MALE; NEUTROPHILS; PNEUMONIA; QUARTZ; RATS; RATS, INBRED STRAINS; REACTION TIME; SILICON DIOXIDE; SPECIFIC PATHOGEN-FREE ORGANISMS; TITANIUM;

EID: 0036892075     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.1080/01902140260426742     Document Type: Article

References (24)

1. Rossi AG, Haslett C: Inflammation, cell injury, and apoptosis. In: Said SI, ed. Proinflammatory and Antiinflammatory Peptides. New York: Marcel Dekker; 1998:9-24.
2. Leigh, J, Wang J, Bonin A, Peters M, Ruan X: Silica-induced apoptosis in alveolar and granulomatous cells in vivo. Environ Health Perspect. 1997;105 (Suppl 5):1241-1245.
3. Savill JS, Haslett C: Fate of neutrophils. In: Hellewell PC, Williams TJ, eds. Immunopharmacology of Neutrophils. London: Alcademic Press, 1994:295-314.
4. Anderson GP: Resolution of chronic inflammation by therapeutic induction of apoptosis. TIPS. 1996;17:438-442.
5. Newman SL, Henson JE, Henson PM: Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J Exp Med. 1982;156:430-442.
6. Sanui H, Yoshia SI, Nomoto K, Ohhara R, Adachi Y: Peritoneal macrophages which phagocytose autologous polymorphonuclear leukocytes in guinea pigs. I. Induction by irritants and microorganisms and inhibition by colchicine. Br J Exp. Pathol. 1982;63:278-284.
7. Hagimoto N, Kuwano K, Miyazaki H, Kunitake R, Fujita M, Kawasaki M, Kaneko Y, Hara N: Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. Am J Respir Cell Mol Biol. 1997;17:272-278.
8. Hagimoto N, Kuwano K, Nomoto Y, Kunitake R, Hara N: Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol. 1997;16:91-101.
9. Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett C: Macrophage phagocytosis of aging neutrophils in inflammation: Programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest. 1989;83:865-875.
10. Savill J, Fadok V: Corpse clearance defines the meaning of cell death. Nature. 2000;407:784-787.
11. Haslett C: Granulocyte apoptosis and its role in the resolution and control of lung inflammation. Am J Respir Crit Care Med. 1999;160:S5-S11.
12. Cox, G, Crossley J, Xing Z: Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am J Respir Cell Mol Biol 1995;12:232-237.
13. Borges VM, Falcao H, Leite-Junior JH, Alvim L, Teixeira GP, Russo M, Nobrega AF, Lopes MF, Rocco PM, Davidson WF, Linden R, Yagita H, Zin WA, DosReis GA: Fas ligand triggers pulmonary silicosis. J Exp Med. 2001;194:155-163.
14. Kitamura Y, Hashimoto S, Mizuta N, Kobayashi A, Kooguchi K, Fujiwara I, Nakajima H: Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice. Am J Crit Care Med. 2001;163:762-769.
15. Warheit DB, Carakostas MC, Hartsky MA, Hansen JF: Development of a short-term inhalation bioassay to assess pulmonary toxicity, of inhaled particles: Comparisons of pulmonary responses to carbonyl iron and silica. Toxicol Appl Pharmacol. 1991;107:350-368.
16. Warheit DB, Hansen JF, Yuen IS, Kelly DP, Snajdr SI, Hartsky MA: Inhalation of high concentrations of low toxicity dusts in rats results in impaired pulmonary clearance mechanisms and persistent inflammation. Toxicol Appl Pharmacol. 1997;145:10-22.
17. Gavett SH, Carakostas MC, Belcher LA, Warheit DB: Effect of circulating neutrophil depletion on lung injury induced by inhaled silica particles. J Leuk Biol. 1992;51:455-461.
18. Iyer R, Hamilton RF, Li L, Holian A: Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages. Toxicol Appl Pharmacol. 1996;141:84-92.
19. Sarih M, Souvannavong V, Brown SC, Adam A: Silica induces apoptosis in macrophages and the release of interleukin-1α and interleukin1-β. J Leuk Biol. 1993;54:407-413.
20. Bingisser R, Stey C, Weller M, Groscurth, Russi PE, Frei K: Apoptosis in human alveolar macrophages is induced by endotoxin and is modulated by cytokines. Am J Respir Mol Biol. 1996;15:64-70.
21. Boudreau N, Sympson CJ, Werb Z, Bissell MJ: Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science. 1995;267:891-893.
22. Renvoize C, Bopa A. Pallardy M, Breard J: Apoptosis: Identification of dying cells. Cell Biol Toxicol. 1998;14:111-120.
23. Seki Y, Kai H, Kai M, Muraishi A, Adachi K, Imaizumi T: Mycocardial DNA strand breaks are detected in biopsy tissue from patients with dilated cardiomyopathy. Clin Carciol. 1998;21:591-596.
24. Zhang A, Shen H-M, Zhang Q-F, Ong C-N: Critical role of GSH in silica-induced oxidative stress, cytotoxicity, and genotoxicity in alveolar macrophages. Am J Physiol Lung Cell Mol Physiol. 1999;277:L743-L748.