Neuropathological diagnosis of Alzheimer's disease in forensic autopsy of elderly persons with fatal accident

Legal Medicine

Volumn 4, Issue 4, 2002, Pages 223-231

  Ng'walali, Paul M ^a   Yonemitsu, Kosei ^a   Kibayashi, Kazuhiko ^b   Tsunenari, Shigeyuki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

Author keywords

Accident; Alzheimer's disease; Dementia; Forensic pathology; Immunohistochemistry; Neuropathology; Silver stain

Indexed keywords

SILVER;

ACCIDENT; ACCIDENTAL DEATH; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; DEMENTIA; FATALITY; FEMALE; FORENSIC PATHOLOGY; GERIATRIC PATIENT; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROPIL THREAD; SENILE PLAQUE; SILVER STAINING; STATISTICAL SIGNIFICANCE; VASCULAR AMYLOIDOSIS;

EID: 0036891246     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1344-6223(02)00037-8     Document Type: Article

References (28)

1. Corey TS, Weakley-Jones B, Nichols 2nd GR, Theuer HH. Unnatural deaths in nursing home patients. J Forensic Sci 1992;32:222-227.
2. Ott A, Breteler MMB, van Harskamp F, Claus JJ, van der Cammen TJM, Grobbee DE, Hofman A. Prevalence of Alzheimer's disease and vascular dementia: association with education. The Rotterdam study. Br Med J 1995;310:970-973.
3. Johansson K, Bronge L, Lundberg C, Persson A, Seideman M, Viitanen M. Can a physician recognize an older driver with increased crash risk potential? J Am Geriatr Soc 1996;44:1198-1204.
4. Buchner DM, Larson EB. Falls and fractures in patients with Alzheimer-type dementia. J Am Med Assoc 1987;257:1492-1495.
5. Osculati A, Fassina G. Two cases of accidental asphyxia by neck compression between bed bars. Am J Forensic Med Pathol 2000;21:217-219.
6. Walsh JS, Welch HG, Larson EB. Survival of outpatients with Alzheimer-type dementia. Ann Intern Med 1990;113:429-434.
7. Tomlinson BE. Ageing and the dementias. In: Adams JH, Duchen LW, editors.; London: Edward Arnold, Greenfield's Neuropathology, 5th ed. 1992. pp. 1284-1410.
8. Khachaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol 1985;42:1097-1105.
9. Mirra SS, Heymann A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L. The consortium to establish a registry for Alzheimer's disease (CERAD): Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486.
10. Shi ZR, Itzkowitz SH, Kim YS. A comparison of three immunoperoxidase techniques for antigen detection in colorectal carcinoma tissues. J Histochem Cytochem 1988;36:217-322.
11. Shin R-W, Iwaki T, Kitamoto T, Tateishi J. Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues. Lab Invest 1991;64:693-702.
12. Buttner A, Weis S, Mall G, Gall C, Eisenmenger W. The diagnostic relevance of cerebral amyloid angiopathy in the setting of forensic pathology - a report of two cases and review of the literature. Legal Med 2001;3:141-148.
13. Braak H, Braak E, Grundke II Iqb, al K. Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: A third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques. Neurosci Lett 1986;65:351-355.
14. Molsa PK, Marttila RJ, Rinne UK. Survival and cause of death in Alzheimer's disease and multi-infarct dementia. Acta Neurol Scand 1986;74:103-107.
15. Dickson DW. The pathogenesis of senile plaques. J Neuropathol Exp Neurol 1997;56:321-339.
16. Dickson DW, Farlo J, Davies P, Crystal H, Fuld P, Yen SC. Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques. Am J Pathol 1988;132:86-101.
17. Davis DG, Schmitt FA, Wekstein DR, Markesbery WR. Alzheimer neuropathologic alterations in aged cognitively normal subjects. J Neuropathol Exp Neurol 1999;58:376-388.
18. Hulette CM, Welsh-Bohmer KA, Murray MG, Saunders AM, Mash DC, McIntyre LM. Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals. J Neuropathol Exp Neurol 1998;57:1168-1174.
19. Morris JC, Storandt M, McKeel DW, Rubin EH, Price JL Grant EA, Berg L. Cerebral amyloid deposition and diffuse plaques in 'normal' aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology 1996;46:707-719.
20. Morris JC. Is Alzheimer's disease inevitable with age? J Clin Invest 1999;104:1171-1173.
21. Vonsattel JPG, Myers RH, Hedley-Whyte ET, Ropper AH, Bird ED, Richardson EP. Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study. Ann Neurol 1991;30:637-649.
22. Braak H, Braak E. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol Aging 1995;16:271-284.
23. Mori H, Hamada Y, Kawaguchi M, Honda T, Kondo J, Ihara Y. A distinct form of tau is selectively incorporated into Alzheimer's paired helical filaments. Biochem Biophys Res Commun 1989;159:1221-1226.
24. Perry G, Kawai M, Tabaton M, Onorato M, Mulvihill P, Richey P, Morandi A, Connolly JA, Gambetti P. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton. J Neurosci 1991;11:1748-1755.
25. Papasozomenos SC, Su Y. Altered phosphorylation of τ protein in heat-shocked rats and patients with Alzheimer disease. Proc Natl Acad Sci USA 1991;88:4543-4547.
26. Viitanen M, Johansson K, Bogdanovic N, Berkowicz A, Druid H, Eriksson A, Krantz P, Laaksonen H, Sandler H, Saukko P, Thiblin I, Winblad B, Kalimo H. Alzheimer changes are common in aged drivers killed in single car crashes and at intersections. Forensic Sci Int 1998;96:115-127.
27. Roberts GW, Gentleman SM, Lynch A, Murray L, Landon M, Graham DI. β-Amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry 1994;57:419-425.
28. Hauw J-J, Duyckaerts C, Delaere P. Alzheimer's disease. In: Duckett S, editor. The pathology of the aging human nervous system, Philadelphia, PA: Lea and Febiger, 1991. pp. 113-147.