Muscarinic receptors: A novel therapeutic target for drug addiction

Trends in Pharmacological Sciences

Volumn 23, Issue 12, 2002, Pages 551-

  Yang, Guodong ^a  

^a Ningbo Addiction Research and Treatment Center   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; AMPHETAMINE; ATROPINE; BELLADONNA ALKALOID; COCAINE; DIAMORPHINE; DOPAMINE; HYOSCYAMINE; LIGAND; MORPHINE; MUSCARINIC M5 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; NICOTINE; OPIATE; SCOPOLAMINE;

ANALGESIC ACTIVITY; BRAIN LEVEL; CELL ACTIVATION; DATURA STRAMONIUM; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG DETOXIFICATION; DRUG EFFICACY; DRUG TARGETING; ELECTROSTIMULATION; EVOKED RESPONSE; FOREBRAIN; HERBAL MEDICINE; HEROIN DEPENDENCE; IMMUNOPRECIPITATION; LETTER; MICROINJECTION; MORPHINE TOLERANCE; NERVE CELL STIMULATION; NEUROMODULATION; NONHUMAN; NUCLEUS ACCUMBENS; OPIATE ADDICTION; PLACE PREFERENCE; PODOPHYLLUM; PONS; PRIORITY JOURNAL; REWARD; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM; WITHDRAWAL SYNDROME;

ANIMALS; HUMANS; MICE; MICE, TRANSGENIC; MUSCARINIC ANTAGONISTS; RECEPTOR, MUSCARINIC M5; RECEPTORS, MUSCARINIC; SUBSTANCE-RELATED DISORDERS;

EID: 0036890840     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(02)02133-8     Document Type: Letter

References (3)

1. Basile A.S., et al. Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia. Proc. Natl. Acad. Sci. U. S. A. 99:2002;11452-11457.
2. 5 muscarinic receptors are required for prolonged accumbal dopamine release after electrical stimulation of the pons in mice. J. Neurosci. 21, RC190 (1-6).
3. Yang G., et al. Clinical study of scopolamine detoxification for the treatment of heroin addicts. Natl. Med. J. China. 76:1996;141-144.