Tumor hypoxia is important in radiotherapy, but how should we measure it?

International Journal of Radiation Oncology Biology Physics

Volumn 54, Issue 5, 2002, Pages 1299-1301

  Brown, J Martin ^a,b   Le, Quynh Thu ^a  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE; CARBONIC ANHYDRATASE 9; LYASE; NITROIMIDAZOLE DERIVATIVE; PIMONIDAZOLE; TRANSCRIPTION FACTOR; TUMOR MARKER; UNCLASSIFIED DRUG;

CANCER RADIOTHERAPY; CANCER SURGERY; CELL HYPOXIA; CELL INVASION; CORRELATION ANALYSIS; DISEASE COURSE; EDITORIAL; HEAD TUMOR; HISTOCHEMISTRY; HUMAN; HYPOXEMIA; HYPOXIC CELL; IMMUNOHISTOCHEMISTRY; MEASUREMENT; NECK TUMOR; OXYGEN ELECTRODE; OXYGENATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ASSAY; RADIOSENSITIVITY; SOLID TUMOR; STAINING; STANDARD; SUPERFICIAL CANCER; TISSUE NECROSIS; TISSUE OXYGENATION; TREATMENT OUTCOME; TUMOR BIOPSY; TUMOR BLOOD FLOW; TUMOR CELL; TUMOR RESISTANCE;

CELL HYPOXIA; ELECTRODES; HEAD AND NECK NEOPLASMS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOPLASMS; OXYGEN; TRANSCRIPTION FACTORS;

EID: 0036890714     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(02)03936-6     Document Type: Editorial

References (4)

1. Lando D., Peet D.J., Whelan D.A., et al. Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science. 295:2002;858-861.
2. Aebersold D.M., Burri P., Beer K.T., et al. Expression of hypoxia-inducible factor-1alpha A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer . Cancer Res. 61:2001;2911-2916.
3. Beasley N.J., Leek R., Alam M., et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer Relationship to tumor biology and treatment outcome in surgically resected patients . Cancer Res. 62:2002;2493-2497.
4. Haugland H.K., Vukovic V., Pintilie M., et al. Expression of hypoxia-inducible factor-1alpha in cervical carcinomas Correlation with tumor oxygenation . Int J Radiat Oncol Biol Phys. 53:2002;854-861.