Identification of residues involved in the substrate specificity of human and murine dCK

Biochemical Pharmacology

Volumn 64, Issue 11, 2002, Pages 1559-1567

  Usova, Elena V ^a   Eriksson, Staffan ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Deoxycytidine kinase; Phosphate donor; Site directed mutagenesis; Substrate specificity

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTARABINE; DEOXYCYTIDINE KINASE; GEMCITABINE; GUANINE ARABINOSIDE; ISOENZYME; MUTANT PROTEIN; NUCLEOSIDE DERIVATIVE; PHOSPHATE; URIDINE TRIPHOSPHATE; ZALCITABINE;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; RODENT;

AMINO ACID SEQUENCE; ANIMALS; DEOXYCYTIDINE KINASE; HUMANS; KINETICS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEOSIDES; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0036890013     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01389-8     Document Type: Article

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