In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation

Molecular and Cellular Biology

Volumn 22, Issue 23, 2002, Pages 8375-8387

  Piva, Roberto ^a   Liu, Jian ^a   Chiarle, Roberto ^a   Podda, Antonello ^a   Pagano, Michele ^a   Inghirami, Giorgio ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CULLIN; F BOX PROTEIN; LIGASE; MYC PROTEIN; PROTEIN SKP1; SCF LIGASE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL TRANSFORMATION; CENTROSOME; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DELETION MUTANT; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE STRUCTURE; HUMAN; HUMAN CELL; HYPOPLASIA; KARYOTYPE; LATENT PERIOD; LYMPHOID CELL; MALIGNANT TRANSFORMATION; MITOSIS SPINDLE; NONHUMAN; ONCOGENE C MYC; PENETRANCE; PHENOTYPE; PLOIDY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; T LYMPHOCYTE; TRANSGENIC MOUSE; TUMOR CELL;

ANIMALS; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINEAGE; CELL TRANSFORMATION, NEOPLASTIC; CENTROSOME; CULLIN PROTEINS; GENES, MYC; HUMANS; LYMPHOID TISSUE; LYMPHOMA; MICE; MICE, NUDE; MICE, TRANSGENIC; MITOTIC SPINDLE APPARATUS; MUTATION; PEPTIDE SYNTHASES; PHENOTYPE; S-PHASE KINASE-ASSOCIATED PROTEINS; SKP CULLIN F-BOX PROTEIN LIGASES; SURVIVAL RATE; T-LYMPHOCYTES;

ANIMALIA; MUS MUSCULUS;

EID: 0036888909     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.23.8375-8387.2002     Document Type: Article

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