Mining the Chemical Abstracts database with pharmacophore-based queries

Journal of Molecular Graphics and Modelling

Volumn 21, Issue 3, 2002, Pages 185-194

  Bremner, John B ^a   Castle, Kao ^a   Griffith, Renate ^b   Keller, Paul A ^a   Ridley, Damon D ^c  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

1 Adrenoceptor subtypes; 2D query; 3D pharmacophore; Computer aided drug design; Database mining; High throughput virtual screening; SciFinder Scholar ; Selective antagonists

Indexed keywords

AROMATIC COMPOUNDS; DATABASE SYSTEMS;

RING SKELETONS;

DRUG PRODUCTS;

ADRENERGIC RECEPTOR BLOCKING AGENT; CARBAZOLE DERIVATIVE; TETRAHYDROISOQUINOLINE; ALPHA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ARTICLE; CHEMICAL STRUCTURE; DATA BASE; HYBRID; MOLECULAR MECHANICS; PHARMACOPHORE; PRIORITY JOURNAL; ALGORITHM; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; FACTUAL DATABASE; HUMAN; STRUCTURE ACTIVITY RELATION;

ADRENERGIC BETA-ANTAGONISTS; ALGORITHMS; DATABASES, FACTUAL; DRUG DESIGN; HUMANS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036888354     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1093-3263(02)00141-9     Document Type: Article

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