A comparison of the plaque-inhibitory properties of stannous fluoride and low-concentration chlorhexidine mouthrinses

Journal of Clinical Periodontology

Volumn 29, Issue 12, 2002, Pages 1072-1077

  Claydon, N ^a   Smith, S ^b   Stiller, S ^b   Newcombe, R G ^c   Addy, M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Amine fluoride; Chlorhexidine; Clinical trial; Mouthrinses; Oral hygiene; Plaque; Stannous flouride

Indexed keywords

AMINE FLUORIDE SOLUTION; ANTIINFECTIVE AGENT; CHLORHEXIDINE; FLUORIDE VARNISH; TIN FLUORIDE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; CHEMISTRY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; FEMALE; HUMAN; MALE; MIDDLE AGED; MOUTH HYGIENE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; TOOTH PLAQUE;

ADULT; ANALYSIS OF VARIANCE; ANTI-INFECTIVE AGENTS; CHLORHEXIDINE; CROSS-OVER STUDIES; DENTAL PLAQUE; DENTAL PLAQUE INDEX; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUORIDES, TOPICAL; HUMANS; MALE; MIDDLE AGED; MOUTHWASHES; SINGLE-BLIND METHOD; TIN FLUORIDES;

EID: 0036886304     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-051X.2002.291204.x     Document Type: Article

References (39)

1. Addy, M. (1986) Chlorhexidine compared with other locally delivered antimicrobials. A short review. Journal of Clinical Periodontology 13, 957-964.
2. Addy, M. & Moran, J. M. (1997) Evaluation of oral hygiene products: science is true; don't be misled by the facts. In: Addy, M. & Moran, J.M. (eds): Toothpaste, Mouthrinse and other Topical Remedies in Periodontics, Periodontology 2000 15, 40-51.
3. Addy, M., Wade, W. G., Jenkins, S. & Goodfield, S. (1989) Comparison of two commercially available chlorhexidine mouthrinses. I. Staining and anti-microbial effects. Clinical Preventive Dentistry 11, 10-14.
4. Addy, M., Willis, L. & Moran, J. (1983) The effect of toothpaste and chlorhexidine rinses on plaque accumulation during a 4 day period. Journal of Clinical Periodontology 10, 89-98.
5. Barkvoll, P., Rolla, G. & Svendsen, A. (1989) Interaction between chlorhexidine digluconate and sodium lauryl sulphate in vivo. Journal of Clinical Periodontology 16, 593-598.
6. Bonesvoll, P., Lokken, P. & Rolla, G. (1974) Influence of concentration, time, temperature and pH on the retention of chlorhexidine in the human oral cavity after mouthrinses. Archives of Oral Biology 19, 1025-1029.
7. Brecx, M., Netuschil, I., Reichert, B. & Schreil, G. (1990) Efficacy of Listerine, Meridol and chlorhexidine mouthrinses on plaque, gingivitis and plaque bacteria vitality. Journal of Clinical Periodontology 17, 292-297.
8. Brecx, M., Brownstone, E., MacDonald, L., Gelskey, S. & Cheang, M. (1992) Efficacy of Listerine, Meridol and chlorhexidine mouthrinses as supplements to regular tooth-cleaning measures. Journal of Clinical Periodontology 19, 202-207.
9. Brecx, M., MacDonald, L. L., Legary, K., Cheang, M. & Forgay, M. G. E. (1993) Long term effects of Meridol and chlorhexidine mouthrinses on plaque, gingivitis, staining and bacterial vitality. Journal of Dental Research 72, 1194-1197.
10. Cancro, L. P., Klein, K. & Picozzi, A. (1973) Dose-response of chlorhexidine gluconate in a model in vivo plaque system. Journal of Dental Research 52, 223.
11. Cancro, L. P., Paulovich, D. B., Bolton, S. & Picozzi, A. (1974) Dose-response of chlorhexidine gluconate in a model in vivo plaque system. Journal of Dental Research 53, 765.
12. Claydon, N. & Addy, M. (1995) The use of plaque area and plaque index to measure the effect of fluoride and chlorhexidine toothpastes on 24 hour plaque regrowth. Journal of Clinical Periodontology 22, 540-542.
13. Claydon, N. & Addy, M. (1999) A 24-h regrowth study to evaluate the plaque inhibitory properties of a proprietary liquid dentifrice. Journal of Clinical Periodontology 26, 286-288.
14. Claydon, N., Hunter, L., Moran, J., Wade, W, Kelty, E., Movert, R. & Addy, M. (1996) A 6-month home-usage trial of 0.1% and 0.2% delmopinol mouthwashes. 1. Effects on plaque, gingivitis, supragingival calculus and tooth staining. Journal of Clinical Periodontology 23, 220-228.
15. Eriksen, H. M., Gjermo, P. & Johansen, J. R. (1973) Results from two years use of chlorhexidine containing dentifrices. Helvetica Odontologica Acta 17, 52.
16. Flotra, L., Gjermo, P., Rolla, G. & Waerhaug, J. (1971) Side effects of chlorhexidine mouthwashes. Scandinavian Journal of Dental Research 79, 119-125.
17. Gjermo, P. (1989) Chlorhexidine and related compounds. Journal of Dental Research 68, 1602-1608.
18. Gjermo, P. & Eriksen, H. (1972) The effects of chlorhexidine containing dentifrices. Caries Research 6, 72-74.
19. Gjermo, P. & Rolla, G. (1970) Plaque inhibition by antibacterial dentifrices. Scandinavian Journal of Dental Research 78, 464-470.
20. Gjermo, P. & Rolla, G. (1971) Plaque inhibiting effect of chlorhexidine containing dentifrices. Scandinavian Journal of Dental Research 79, 126-132.
21. Harrap, G. J. (1974) Assessment of the effect of dentifrices on the growth of dental plaque. Journal of Clinical Periodontology 1, 166-174.
22. Heasman, P. A. & Seymour, R. A. (1994) Pharmacological control of periodontal disease. 1. Antiplaque agents. Journal of Dentistry 22, 323-336.
23. Hull, P. S. (1980) Chemical inhibition of plaque. Journal of Clinical Periodontology 7, 431-442.
24. Jackson, R. J. (1997) Metal salts, essential oils and phenols-old or new? In: Addy, M. & Moran, J. M. (eds): Toothpaste, Mouthrinse, and other Topical Remedies in Periodontics. Periodontology, 2000 15, 63-73.
25. Jenkins, S., Addy, M. & Newcombe, R. (1989) Comparison of two commercially available chlorhexidine mouthrinses. II. Effects on plaque reformation, gingivitis and toothstaining. Clinical Preventive Dentistry 1989 11, 12-16.
26. Jenkins, S., Addy, M. & Newcombe, R. (1994) Dose-response of chlorhexidine against plaque and comparison with triclosan. Journal of Clinical Periodontology 21, 250-255.
27. Johansen, J. R., Gjermo, P. & Eriksen, H. M. (1972) A longitudinal study on the effect of chlorhexidine containing dentifrices. Journal of Periodontal Research 7, 36-37.
28. Johansen, J. R., Gjermo, P. & Eriksen, H. M. (1975) Effect of two years use of chlorhexidine containing dentifrices on plaque, gingivitis and caries. Scandinavian Journal of Dental Research 83, 288-292.
29. Jones, C. G. (1997) Chlorhexidine: is it still the gold standard? In: Addy, M. & Moran, J. M. (eds): Toothpaste, Mouthrinse, and other Topical Remedies in Periodontics. Periodontology, 2000 15, 55-62.
30. Kornman, K. S. (1986) Antimicrobial agents. In: Loe, H. & Kleinman, D. V. (eds): Dental Plaque Control Measures and Oral Hygiene Practices. Oxford: IRL Press, pp 121-142.
31. Mandel, I. D. (1988) Chemotherapeutic agents for controlling plaque and gingivitis. Journal of Clinical Periodontology 15, 488-494.
32. Moran, J. M. (1997) Chemical plaque control-prevention for the masses. In: Addy, M. & Moran, J. M. (eds): Toothpaste, Mouthrinse, and other Topical Remedies in Periodontics. Periodontology, 2000 15, 109-117.
33. Moran, J., Addy, M., Newcombe, R. G. & Marlow, I. (2001) A study to assess the plaque inhibitory action of a newly formulated toothpaste. Journal of Clinical Periodontology 28, 86-89.
34. Owens, J., Addy, M., Faulkner, J., Lockwood, C. & Adair, R. (1997) A short term clinical study to investigate the chemical inhibitory properties of mouthrinses when used as adjuncts to toothpastes: applied to chlorhexidine. Journal of Clinical Periodontology 24, 732-737.
35. Quigley, G. & Hein, J. (1962) Comparative cleansing efficiency of manual and power brushing. Journal of the American Dental Association 65, 26-29.
36. Shaw, L. & Murray, J. J. (1977) A new index for measuring extrinsic stains in clinical trials. Community Dentistry and Oral Epidemiology 5, 116-120.
37. Sjoblom, M., Ainamo, A. & Aimamo, J. (1976) Antimicrolbial effect of four different toothpastes. Scandinavian Journal of Dental Research 84, 377-380.
38. Turesky, S., Gilmore, N. D. & Glickman, I. (1970) Reduced plaque formation by the chloromethyl analogue of Victamine C. Journal of Periodontology 41, 41-43.
39. Yates, R., Moran, J., Addy, M., Mullan, P. J., Wade, W. & Newcombe, R. (1997) The comparative effect of acidified sodium chlorite and chlorhexidine mouthrinses on plaque regrowth and salivary bacterial counts. Journal of Clinical Periodontology 24, 603-609.