Microinjection of an adenosine A1 agonist into the medial pontine reticular formation increases tail flick latency to thermal stimulation

Anesthesiology

Volumn 97, Issue 6, 2002, Pages 1597-1601

  Tanase, Diana ^b   Baghdoyan, Helen A ^a   Lydic, Ralph ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N (4 SULFOPHENYL)ADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; SODIUM CHLORIDE; 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; ADENOSINE RECEPTOR; ANALGESIC AGENT; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CAT; CONTROLLED STUDY; MALE; MICROINJECTION; NONHUMAN; PAIN; PONS RETICULAR FORMATION; PRIORITY JOURNAL; REM SLEEP; SLEEP DEPRIVATION; SLEEP WAKING CYCLE; TAIL FLICK TEST; THERMAL STIMULATION; ANIMAL; DRUG EFFECT; DRUG POTENTIATION; HEAT; SLEEP; TAIL;

ANALGESICS; ANIMALS; CATS; HEAT; MALE; MICROINJECTIONS; PAIN; RECEPTORS, PURINERGIC P1; SLEEP; TAIL; XANTHINES;

EID: 0036885111     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200212000-00036     Document Type: Article

References (49)

1. Bonica JJ: General considerations of chronic pain, The Management of Pain, 2nd Edition. Edited by Bonica JJ. Philadelphia, Lea & Febiger, 1990, pp 180-96
2. Rosenberg-Adamsen S, Kehlet H, Dodds C, Rosenberg J: Postoperative sleep disturbances: Mechanisms and clinical implications. Br J Anaesth 1996; 76:552-9
3. Lamberg L: Chronic pain linked with poor sleep: Exploration of causes and treatment. JAMA 1999; 281:691-2
4. Kay DC, Eisenstein RB, Jasinski DR: Morphine effects on human REM state, waking state, and NREM sleep. Psychopharmacology 1969; 14:404-16
5. Sitaram N, Gillin JC: The effect of naloxone on normal human sleep. Brain Res 1982; 244:387-92
6. Keifer JC, Baghdoyan HA, Lydic R: Sleep disruption and increased apneas after pontine microinjection of morphine. Anesthesiology 1992; 77:973-82
7. Cronin A, Keifer JC, Baghdoyan HA, Lydic R: Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist. Br J Anaesth 1995; 74:188-92
8. Robert C, Stinus L, Limoge A: Sleep impairments in rats implanted with morphine pellets. Neuropsychobiology 1999; 40:214-7
9. Kruger JM: Immunological alterations in arousal states, Handbook of Behavioral State Control: Cellular and Molecular Mechanisms. Edited by Lydic R, Baghdoyan HA. Boca Raton, FL, CRC Press, 1999, pp 609-700
10. Everson CA, Toth LA: Systemic bacterial invasion induced by sleep deprivation. Am J Physiol 2000; 278:R905-16
11. Dunwiddie TV, Masino SA: The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci 2001; 24:31-55
12. Sawynok J: Adenosine receptor activation and nociception. Eur J Pharmacol 1998; 347:1-11
13. Keil GJ, DeLander GE: Altered sensory behaviors in mice following manipulation of endogenous spinal adenosine neurotransmission. Eur J Pharmacol 1996; 312:7-14
14. Segerdahl M, Irestedt L, Sollevi A: Antinociceptive effect of perioperative adenosine infusion in abdominal hysterectomy. Acta Anaesthesiol Scand 1997; 41:473-9
15. Segerdahl M, Ekblom A, Sandelin K, Wickman M, Sollevi A: Peroperative adenosine infusion reduces the requirements for isoflurane and postoperative analgesics. Anesth Analg 1995; 80:1145-9
16. Rane K, Segerdahl M, Goiny M, Sollevi A: Intrathecal adenosine administration: A phase 1 clinical safety study in healthy volunteers, with additional evaluation of its influence on sensory thresholds and experimental pain. Anesthesiology 1998; 89:1108-15
17. Gyllenhammar E, Nordfors LO: Systemic adenosine infusions alleviated neuropathic pain. Pain 2001; 94:121-2
18. Ekblom A, Segerdahl M, Sollevi A: Adenosine increases the cutaneous heat pain threshold in healthy volunteers. Acta Anaesthesiol Scand 1995; 39:717-22
19. Belfrage M, Segerdahl M, Arner S, Sollevi A: The safety and efficacy of intrathecal adenosine in patients with chronic neuropathic pain. Anesth Analg 1999; 89:136-42
20. Sjolund KF, Belfrage M, Karlsten R, Segerdahl M, Arner S, Gordh T, Sollevi A: Systemic adenosine infusion reduces the area of tactile allodynia in neuropathic pain following peripheral nerve injury: A multi-centre, placebo-controlled study. Eur J Pain 2001; 5:199-207
21. Porkka-Heiskanen T, Strecker RE, Thakkar M, Bjorkum AA, Greene RW, McCarley RW: Adenosine: A mediator of the sleep-inducing effects of prolonged wakefulness. Science 1997; 276:1265-8
22. Strecker RE, Morairty S, Thakkar MM, Porkka-Heiskanen T, Basheer R, Dauphin LJ, Rainnie DG, Portas CM, Greene RW, McCarley RW: Adenosinergic modulation of basal forebrain and preoptic/anterior hypothalamic neuronal activity in the control of behavioral state. Behav Brain Res 2000; 115:183-204
23. Lydic R, Baghdoyan HA (eds): Handbook of Behavioral State Control: Cellular and Molecular Mechanisms. Boca Raton, FL, CRC Press, 1999; pp 1-700
24. Kshatri AM, Baghdoyan HA, Lydic R: Cholinomimetics, but not morphine, increase antinociceptive behavior from pontine reticular regions regulating rapid-eye-movement sleep. Sleep 1998; 21:677-85
25. 1 agonist into feline medial pontine reticular formation (mPRF) increases tail flick latency (TFL) to thermal stimulation. Soc Neurosci Abstr 2001; 27:1376
26. Chase MH, Morales FR: Control of motoneurons during sleep, Principles and Practice of Sleep Medicine, 3rd Edition. Edited by Kryger MH, Roth T, Dement WC. Philadelphia, W.B. Saunders, 2000, pp 155-68
27. Carstens E, Campbell IG: Parametric and pharmacological studies of midbrain suppression of the hind limb flexion withdrawal reflex in the rat. Pain 1988; 33:201-13
28. Hayes RL, Katayama Y, Watkins LR, Becker DP: Bilateral lesions of the dorsolateral funiculus of the cat spinal cord: Effects on basal nociceptive reflexes and nociceptive suppression produced by cholinergic activation of the pontine parabrachial region. Brain Res 1984; 311:267-80
29. Ursin R, Sterman MB: A Manual for Standardized Scoring of Sleep and Waking States in the Adult Cat. Los Angeles, Brain Information Services/Brain Res Institute, University of California, 1981; pp 1-103
30. 1 receptor agonist. Sleep 2001; 24:52-62
31. Kryger MH, Roth T, Dement WC (eds): Principles and Practice of Sleep Medicine, 3rd Edition. Philadelphia, W.B. Saunders, 2000, pp 1-1067
32. Berman AL: The Brain Stem of the Cat: A Cytoarchitectonic Atlas with Stereotaxic Coordinates. Madison, WI, The University Press, 1968; pp 1-175
33. Marks GA, Birabil CG: Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation. Neuroscience 1998; 86:29-37
34. Portas CM, Thakkar M, Rainnie DG, Greene RW, McCarley RW: Role of adenosine in behavioral state modulation: A microdialysis study in the freely moving cat. Neuroscience 1997; 79:225-35
35. Lavie P, Pratt H, Scharf B, Peled R, Brown J: Localized pontine lesion: Nearly total absence of REM sleep. Neurology 1984; 34:118-20
36. Baghdoyan HA, Lydic R: Neurotransmitters and neuromodulators regulating sleep, Sleep and Epilepsy: The Clinical Spectrum. Edited by Bazil C, Malow B, Sammaritano M. New York, Elsevier Science, 2002, pp 17-44
37. Soja PJ, Pang W, Taepavarapruk N, McErlane SA: Spontaneous spike activity of spinoreticular tract neurons during sleep and wakefulness. Sleep 2001; 24:18-25
38. Soja PJ, Cairns BE, Kristensen MP: Transmission through ascending trigeminal and lumbar sensory pathways: Dependence on behavioral state, Handbook of Behavioral State Control: Cellular and Molecular Mechanisms. Edited by Lydic R, Baghdoyan HA. Boca Raton, FL, CRC Press, 1999, pp 521-44
39. Benington JH, Heller HC: Restoration of brain energy metabolism as the function of sleep. Prog Neurobiol 1995; 45:347-60
40. Chagoya de Sanchez V, Hernandez Munoz R, Suarez J, Vidrio S, Yanez L, Diaz Munoz M: Day-night variations of adenosine and its metabolizing enzymes in the brain cortex of the rat: Possible physiological significance for the energetic homeostasis and the sleep-wake cycle. Brain Res 1993; 612:115-21
41. Radulovacki M: Role of adenosine in sleep in rats. J Basic Clin Physiol Pharmacol 1985; 5:327-39
42. Eisenach JC, Hood DD, Curry R: Phase 1 safety assessment of intrathecal injection of an American formulation of adenosine in humans. Anesthesiology 2002; 96:24-8
43. Eisenach JC, Hood DD, Curry R: Preliminary efficacy assessment of intrathecal injection of an American formulation of adenosine in humans. Anesthesiology 2002; 96:29-34
44. Lydic R: Pain: A bridge linking anesthesiology and sleep research. Sleep 2001; 24:10-2
45. Dripps RD, Eckenhoff JE, Vandam LD (eds): Introduction to Anesthesia: The Principles of Safe Practice, 7th Edition. Philadelphia, W.B. Saunders, 1988, pp 1-499
46. Sandrini G, Milanov I, Rossi B, Murri L, Alfonsi E, Moglia A, Nappi G: Effects of sleep on spinal nociceptive reflexes in humans. Sleep 2001; 24:13-7
47. Kaplan GB, Leite-Morris KA: Up-regulation of adenosine transporter-binding sites in striatum and hypothalamus of opiate tolerant mice. Brain Res 1997; 763:215-20
48. 1-adenosine receptor that is widely expressed in brain and spinal cord. Mol Endocrinol 1991; 5:1037-48
49. Niemi G, Breivik H: Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomised, double-blind, cross-over study with and without adrenaline. Acta Anaesthesiol Scand 1998; 42:897-909