The β2-microglobulin/cystatin C ratio - A potential marker of post-transplant lymphoproliferative disease

Clinical Nephrology

Volumn 58, Issue 6, 2002, Pages 417-422

  Bokenkamp A ^a   Grabensee, A ^a   Stoffel Wagner, B ^a   Hasan, C ^a   Henne, T ^b   Offner, G ^b   Lentze, M J ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

2 microglobulin; Children; Cystatin C; Lymphoproliferation; Post transplant lymphoproliferative disease; Renal function tests

Indexed keywords

BETA 2 MICROGLOBULIN; CYSTATIN C; BIOLOGICAL MARKER; CYSTATIN;

ACUTE DISEASE; ADOLESCENT; ARTICLE; BLOOD ANALYSIS; CHILD; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GLOMERULUS FILTRATION RATE; HEMODIALYSIS PATIENT; HUMAN; IMMUNOLOGICAL PROCEDURES; KIDNEY FAILURE; KIDNEY FUNCTION TEST; KIDNEY TRANSPLANTATION; LYMPHOCYTE PROLIFERATION; LYMPHOPROLIFERATIVE DISEASE; MAJOR CLINICAL STUDY; MALE; NEPHELOMETRY; NEWBORN; PREDICTION; RECIPIENT; REMISSION; SENSITIVITY AND SPECIFICITY; BLOOD; POSTOPERATIVE COMPLICATION; PREDICTION AND FORECASTING; STATISTICAL MODEL;

BETA 2-MICROGLOBULIN; BIOLOGICAL MARKERS; CHILD; CYSTATINS; FEMALE; HUMANS; KIDNEY TRANSPLANTATION; LINEAR MODELS; LYMPHOPROLIFERATIVE DISORDERS; MALE; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY;

EID: 0036882692     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Aziz N, Nishanian P, Mitsuyasu R, Detels R, Fahey JL 1999 Variables that affect assays for plasma cytokines and soluble activation markers. Clin Diagn Lab Immunol 6: 89-95
2. Bökenkamp A, Ciarimboli G, Dieterich C 2001 Cystatin C in a rat model of end-stage renal failure. Ren Fail (in press)
3. Bökenkamp A, Domanetzki M, Zinck R, Schumann G, Byrd D, Brodehl J 1998 Cystatin C - a new marker of glomerular filtration rate in children independent of height and age. Pediatrics 101: 875-881
4. 2-microglobulin and C-reactive protein in the monitoring of lymphomas: findings in a multicenter study and experience in selected patients. Cancer 45: 318-326
5. Finney H, Newman DJ, Gruber W, Merle P, Price CP 1997 Initial evaluation of cystatin C measurement by particle-enhanced immunonephelometry on the Behring nephelometer systems (BNA, BN II). Clin Chem 43: 1016-1022
6. 2-microglobulin as a measure of glomerular filtration rate. Acta Med Scand 218: 499-503
7. Kabanda A, Goffin E, Bernard A, Lauwerys R, van Ypersele de Strihou C 1995 Factors influencing serum levels and peritoneal clearances of low-molecular weight proteins in continuous ambulatory peritoneal dialysis. Kidney Int 48: 1946-1952
8. Kabanda A, Jadoul M, Pochet JM, Lauwerys R, van Ypersele de Strihou C, Bernard A 1994 Determinants of the serum concentration of low-molecular weight proteins in patients on maintenance hemodialysis. Kidney Int 46: 1689-1696
9. Kyhse-Andersen J, Schmidt C, Nordin G, Andersson B, Nilsson-Ehle P, Lindström V, Grubb A 1994 Serum cystatin C, determined by a rapid, automated, particle-enhanced turbidometric method is a better marker than serum creatinine for glomerular filtration rate. Clin Chem 40: 1921-1926
10. Newman DJ, Thakkar H, Edwards RG, Wilkie M, White T, Grubb AO, Price CP 1995 Serum cystatin C measured by automated immunoassay: a more sensitive marker of changes in GFR than serum creatinine. Kidney Int 47: 312-318
11. 2-microglobulin concentrations after allogeneic bone marrow transplantation. J Clin Pathol 40: 657-662
12. 2-microglobulin/cystatin C ratio. Scand J Clin Lab Invest 57: 463-470
13. Pickhardt PJ, Siegel MJ, Hayashi RJ, Kelly M 2000 Posttransplantation lymphoproliferative disorder in children: clinical, histopathologic, and imaging features. Radiology 217: 16-25
14. Randers E, Erlandsen EJ 1999 Serum cystatin C as an endogenous marker of renal function - a review. Clin Chem Lab Med 37: 389-395
15. Randers E, Kornerup K, Erlandsen EJ, Hasling C, Danielsen H 1998 Cystatin C levels in sera of patients with acute infectious diseases with high C-reactive protein levels. Scand J Clin Lab Invest 58 (Suppl 228): 120
16. Schwartz GJ, Haycock GB, Edelman CM, Spitzer A 1976 A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 58: 259-263
17. Solberg HE 1987 Approved recommendation (1987) on the theory of reference values - Part 5. Statistical treatment of collected reference values. Determination of reference limits. J Clin Chem Clin Biochem 25: 645-656
18. 2-microglobulin and acute phase reactant proteins in chronic lymphocytic leukaemia. A multicenter study. Acta Haematol 64: 79-86
19. Stabuc B, Vrhovec L, Stabuc-Silih M, Cizej TE 2000 Improved prediction of decreased creatinine clearance by serum cystatin C: use in cancer patients before and during chemotherapy. Clin Chem 46: 193-197
20. Swinnen LJ 2000a Diagnosis and treatment of transplant-related lymphoma. Ann Oncol 11 (Suppl 1): 45-48
21. Swinnen LJ 2000b Transplantation-related lymphoproliferative disorder: a model for human immunodeficiency virus-related lymphomas. Semin Oncol 27: 402-408
22. 2-M). In: Thomas L (ed) Clinical laboratory diagnostics - Use and assessment of clinical laboratory results. TH-Buch Verlagsgeselischaft, Frankfurt/Main,