Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria in Australian Defence Force personnel

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 96, Issue 6, 2002, Pages 683-684

  Nasveld, Peter ^a,b   Kitchener, Scott ^a,b   Edstein, Michael ^a,b   Rieckmann, Karl ^b  

^a Australian Defence Force   (Papua New Guinea)

^b AUSTRALIAN ARMY MALARIA INSTITUTE   (Australia)

Author keywords

Bougainville Island; Chemotherapy; Malaria; Plasmodium vivax; Primaquine; Tafenoquine

Indexed keywords

PRIMAQUINE; TAFENOQUINE;

ABDOMINAL CRAMP; ARTICLE; AUSTRALIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; EXPOSURE; FEMALE; HEADACHE; HUMAN; HUMAN EXPERIMENT; LETHARGY; MALARIA; MALARIA CONTROL; MALE; NAUSEA AND VOMITING; NORMAL HUMAN; PAPUA NEW GUINEA; PATIENT ATTITUDE; PLASMODIUM VIVAX; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; SOLDIER; TREATMENT OUTCOME; VOLUNTEER;

PLASMODIUM VIVAX; PROTOZOA;

EID: 0036881073     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(02)90351-2     Document Type: Article

References (8)

1. Brueckner, R. P., Coster, T., Wesche, D. L., Shmuklarsky, M. & Schuster, B. G. (1998a). Prophylaxis of Plasmodium falciparum infection in a human challenge model with WR 238605, a new 8-aminoquinoline antimalarial. Antimicrobial Agents and Chemotherapy, 42, 1293-1294.
2. Brueckner, R. P., Lasseter, K. C., Lin, E. T. & Schuster, B. G. (1998b). First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial. American Journal of Tropical Medicine and Hygiene, 58, 645-649.
3. Clyde, D. F. (1981). Clinical problems associated with the use of primaquine as a tissue schizontocidal and gametocytocidal drug. Bulletin of the World Health Organization, 59, 391-395.
4. Heap, B. J. (1988). Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea. Journal of the Royal Army Medical Corps, 134, 128-129.
5. Jelinek, T., Northdurft, H. D., Von Sonnenburg, F. & Loscher, T. (1995). Long-term efficacy of primaquine in the treatment of vivax malaria in nonimmune travelers. American Journal of Tropical Medicine and Hygiene, 52, 322-324.
6. Kocisko, D. A., Walsh, D. S., Eamsila, C. & Edstein, M. D. (2000). Measurement of tafenoquine in human plasma, and venous and capillary blood by high-performance liquid chromatography. Therapeutic Drug Monitor, 22, 184-189.
7. Schwartz, E. & Regev-Yochay, G. (1999). Primaquine as prophylaxis for malaria for nonimmune travelers: a comparison with mefloquine and doxycycline. Clinical Infectious Disease, 29, 1502-1506.
8. Shanks, G. D., Barnett, A., Edstein, M. D. & Rieckmann, K. H. (1995). Effectiveness of doxycycline combined with primaquine for malaria prophylaxis. Medical Journal of Australia, 162, 306-310.