Outcome of severe encephalomyelitis in children: Effect of high-dose methylprednisolone and immunoglobulins

Journal of Child Neurology

Volumn 17, Issue 11, 2002, Pages 810-814

  Shahar, Eli ^a   Andraus, Jameel ^a   Savitzki, David ^a   Pilar, Giora ^a   Zelnik, Nathaniel ^b  

^a MEYER CHILDREN S HOSPITAL   (Israel)

^b CARMEL MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; METHYLPREDNISOLONE;

ADOLESCENT; ARTICLE; ARTIFICIAL VENTILATION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CONVALESCENCE; DEMYELINATING NEUROPATHY; DISABILITY; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; ELECTROENCEPHALOGRAPHY; ENCEPHALOMYELITIS; FECES INCONTINENCE; FEMALE; FLACCID PARALYSIS; HUMAN; MALE; MUSCLE WEAKNESS; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NERVE DISEASE; PARAPLEGIA; POLYRADICULONEUROPATHY; PRIORITY JOURNAL; REMISSION; RESPIRATORY FAILURE; SPINAL CORD DISEASE; TREATMENT INDICATION; TREATMENT OUTCOME; URINE INCONTINENCE; VISUAL IMPAIRMENT;

EID: 0036880069     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/08830738020170111001     Document Type: Article

References (33)

1. Andersen O: Myelitis. Curr Opin Neurol 2000;16:311-316.
2. Rust RS: Multiple sclerosis, acute disseminated encephalomyelitis and related conditions. Semin Pediatr Neurol 2000;7:66-90.
3. Dale RC, de Sousa C, Choung WK, et al: Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis, and multiple sclerosis in children. Brain 2000;123:2407-2422.
4. Straub J, Chofflon M, Delavelle J: Early high-dose intravenous methylprednisolone in acute disseminated encephalomyelitis: A successful recovery. Neurology 1997;49:1145-1147.
5. Lahat E, Pillar G, Ravid S, et al: Rapid recovery from transverse myelopathy in children treated with methylprednisolone. Pediatr Neurol 1998;19:279-282.
6. Sebire G, Hollenburg H, Meyer L, et al: High dose methylprednisolone in severe acute transverse myelopathy. Arch Dis Child 1997;76:167-168.
7. Pasternak JF, De Vivo DC, Prensky AL: Steroid-responsive encephalomyelitis in childhood. Neurology 1998;30:481-486.
8. Knebusch M, Strassburg HM, Reiners K: Acute transverse myelitis in childhood: Nine cases and review of the literature. Dev Med Child Neurol 1998;40:631-639.
9. Apak RA, Kose G, Anlar B, et al: Acute disseminated encephalomyelitis in childhood: Report of 10 cases. J Child Neurol 1999;14:198-201.
10. Kalita J, Guptar PM, Misra UK: Clinical and evoked potential changes in acute transverse myelitis following methylprednisolone. Spinal Cord 1999;37:658-662.
11. Kleiman M, Brunquell P: Acute disseminated encephalomyelitis: Response to intravenous immunoglobulin. J Child Neurol 1995;10:481-483.
12. Hahn JS, Siegler DJ, Enzmann D: Intravenous gammaglobulin therapy in recurrent acute disseminated encephalomyelitis. Neurology 1996;46:1173-1174.
13. Finsterer J, Grass R, Stollberger C, Mamoli B: Immunoglobulins in acute, parainfectious, disseminated encephalomyelitis. Clin Neuropharmacol 1998;21:258-261.
14. Nishikawa M, Ichiyama T, Hayashi T, et al: Intravenous immunoglobulin therapy in acute disseminated encephalomyelitis. Pediatr Neurol 1999;21:583-586.
15. Pradham S, Gupta RP, Shashank S, Pandey N: Intravenous immunoglobulin therapy in acute disseminated encephalomyelitis. J Neurol Sci 1999;165:56-61.
16. Assa A, Watemberg N, Bujanover Y, Lerman-Sagie T: Demyelinative brain stem encephalitis responsive to intravenous immunoglobulin therapy. Pediatrics 1999;104:301-304.
17. Sahlas GJ, Miller SP, Guerin M, et al: Treatment of acute disseminated encephalomyelitis with intravenous immunuglobulin. Neurology 2000;54:1370-1372.
18. Shah AK, Tselis A, Mason B: Acute disseminated encephalomyelitis in a pregnant woman successfully treated with plasmapheresis. J Neurol Sci 2000;15:147-151.
19. Balestri P, Grosso S, Aquaviva A, Bernini M: Plasmapheresis in a child affected by acute disseminated encephalomyelitis. Brain Dev 2000;22:123-126.
20. Straussberg R, Schonfeld T, Weitz R, et al: Improvement of atypical acute disseminated encephalomyelitis with steroids and immunoglobulins. Pediatr Neurol 2001;24:139-143.
21. Reik L Jr: Disseminated vasculomyelinopathy: An immune complex disease. Ann Neurol 1980;7:291-296.
22. Gordon FL, Nguyen KB, White CA, Pender MP: Rapid entry and downregulation of T cells in the central nervous system during the reinduction of experimental autoimmune encephalomyelitis. J Neuroimmunol 2001;112:15-27.
23. Jorens PE, VanderBorgh A, Culemans B, et al: Encephalomyelitis-associated antimyelin autoreactivity induced by streptococcal exotorins. Neurology 2000;54:1433-1441.
24. Stoll G, Jander S, Schroeter M: Cytokines in CNS disorders: Neurotoxicity versus neurprotection. J Neurol Trauma 2000; 59(Suppl):81-89.
25. Bauer J, Stadelman C, Bancher C, et al: Apoptosis of T lymphocytes in acute disseminated encephalomyelitis. Acta Neuropathol (Berl) 1999;97:543-546.
26. Smidt J, Gold R, Schonrock L, et al: T-cell apoptosis in situ in experimental autoimmune encephalomyelitis following methylprednisolone pulse therapy. Brain 2000;123:1431-1441.
27. Achiron A, Miron S: Immunoglobulin treatment in multiple sclerosis and experimental autoimmune encephalomyelitis. Multiple Sclerosis 2000;6(Suppl 2):S5-S8.
28. Kurlander RJ: Reversible and irreversible loss of Fc receptor function of human monocytes as a consequence of interaction with immunoglobulin G. J Clin Invest 1980;66:773-781.
29. Basta M, Dalakas MC: High dose intravenous immunoglobulin exerts its beneficial effect in patients with dermatomyositis by blocking endomyseal deposition on activated complement fragments. J Clin Invest 1994;94:1729-1735.
30. Rodriguez M, Lennon VA: Immunoglobulins promote remyelination in the central nervous system. Ann Neurol 1990;27:12-17.
31. Abe Y, Hortuchi A, Myake M, Kinmura S: Anti-cytokine nature of neutral human immunoglobulin: One possible mechanism of the clinical effect of intravenous immunoglobulin therapy. Immunol Rev 1994;139:5-19.
32. Amit R, Glick B, Itzckak Y, et al: Acute severe combined demyelination. Childs Nerv Syst 1992;8:354-356.
33. Kinoshita A, Hayashi M, Miyamoto K, et al: Inflammatory demyelinating polyradiculitis in a patient with acute disseminated encephalomyelitis (ADEM). J Neurol Neurosurg Psychiatry 1996;60:87-90.