Correlation between BRCA1 expression and apopotosis-related biological parameters in sporadic breast carcinomas

Anticancer Research

Volumn 22, Issue 6 B, 2002, Pages 3615-3619

  Yang, Qifeng ^a,b   Yoshimura, Goro ^a   Nakamura, Misa ^a   Nakamura, Yasushi ^a   Suzuma, Takaomi ^a   Umemura, Teiji ^a   Mori, Ichiro ^a   Sakurai, Takeo ^a   Kakudo, Kennichi ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; BRCA1; Breast cancer; Sporadic

Indexed keywords

BRCA1 PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR DIFFERENTIATION; TUMOR SUPPRESSOR GENE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRCA1 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036875619     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Claus EB, Thompson WD and Risch N: Genetic analysis of breast cancer in the cancer and steroid hormone study. Am J Hum Genet 48: 232-242, 1991.
2. Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B and King MC: Linkage of early onset familial breast cancer to chromosome 17q21. Science 250: 1684-1689, 1990.
3. Miki Y, Swensen J, Shattuck-Edidens D, Futreal PA, Harshman K, Tavtigian S, Lie Q, Cochran C, Bennett LM, Ding W, Bell R, Rosenthal J, Hussey C, Tran T, McClure M, Frye C, Hattier T, Phelps R, Haugen-Strano A, Katcher H, Yakumo K, Gholami Z, Shaffer D, Stone S, Bayer S, Wray C, Bogden R, Dayananth P, Ward J, Tonin P, Narod S, Bristow PK, Norris FH, Helvering L, Morrison P, Lai M, Barrett JC, Lewis C, Neuhausen S, Cannon-Albringht L, Goldgar D, Wiseman R, Kamb A and Skolnick MH: A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266: 66-71, 1994.
4. Couch FJ and Weber BL: Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core. Hum Mutat 8: 8-18, 1996.
5. Newman B, Mu H, Butler LM, Millikan RC, Moorman PG and King MC: Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. JAMA 279: 915-921, 1998.
6. Malone KE, Daling JR, Neal C, Suter NM, O'Brien C, Cushing-Haugen K, Jonasdottir TJ, Thompson JD and Ostrander EA: Frequency of BRCA1/BRCA2 mutations in a population-based sample of young breast carcinoma cases. Cancer 88: 1393-1402, 2000.
7. Peto J, Collins N, Barfoot R, Seal S, Warren W, Rahman N, Easton DF, Evans C, Deacon J and Stratton MR: Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer. J Natl Cancer Inst 91: 943-949, 1999.
8. Malone KE, Daling JR, Thompson JD, O'Brien CA, Francisco LV and Ostrander EA: BRCA1 mutations and breast cancer in the general population: Analyses in women before age 35 years with first-degree family history. JAMA 279: 922-929, 1998.
9. Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett LM, Haugen-Strano A, Swensen J, Miki Y et al.: BRCA1 mutations in primary breast and ovarian carcinomas. Science 266: 120-122, 1994.
10. Merajver SD, Pham TM, Caduff RF, Chen M, Poy EL, Cooney KA, Weber BL, Collins FS, Johnston C and Frank TS: Somatic mutations in the BRCA1 gene in sporadic ovarian tumours. Nat Genet 9: 439-443, 1995.
11. Thompson ME, Jensen RA, Obermiller PS, Page DL and Holt JT: Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat Genet 9: 445-450, 1995.
12. Chen Y, Chen CF, Riley DJ, Allred DC, Chen PL, Von Hoff D, Osborne CK and Lee WH: Aberrant subcellular localization of BRCA1 in breast cancer. Science 270: 789-791, 1995.
13. Ouchi T, Lee SW, Ouchi M, Aaronson SA and Horvath CM: CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc Natl Acad Sci USA 97: 1020-1025, 2000.
14. Zhang H, Somasundaram K, Peng Y, Tian H, Bi D, Weber BL and El-Deiry WS: BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene 16: 1713-1721, 1998.
15. Shao N, Chai YL, Shyam E, Reddy P and Rao VN: Induction of apoptosis by the tumor suppressor protein BRCA1. Oncogene 13: 1-7, 1996.
16. Harkin DP, Bean JM, Bean JM, Miklos D, Song YH, Truong VB, Englert C, Christians FC, Ellisen LW, Maheswaran S, Oliner JD and Haber DA: Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1. Cell 97: 575-586, 1999.
17. WHO: Histological Typing of Breast Tumors, 2nd ed., International Histological Classification of Tumors, No.2. World Health Organization, Geneva, 1981.
18. Elston CW and Ellis IO: Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19: 403-410, 1991.
19. Yang Q, Sakurai T, Jing X, Utsunomiya H, Shan L, Nakamura Y, Nakamura M, Oura S, Suzuma T, Yoshimura G, Umemura T, Kokawa Y and Kakudo K: Expression of Bcl-2, but not Bax, correlates with estrogen receptor status and tumor proliferation in invasive breast carcinoma. Pathol Int 49: 775-780, 1999.
20. Yang Q, Yoshimura G, Sakurai T, Nakamura M, Nakamura Y, Shan L, Suzuma T, Tamaki T, Umemura T, Mori I and Kakudo K: Allelic loss of chromosome 3p24 correlates with tumor progression rather than with retinoic acid receptor β2 expression in breast carcinoma. Breast Cancer Res Treat 70: 39-45, 2001.
21. Yang Q, Sakurai T, Yoshimura G, Takashi Y, Suzuma T, Umemura T, Nakamura Y, Nakamura M, Utsunomiya H, Mori I and Kakudo K: Overexpression p27 protein in human breast cancer correlates with in vitro resistance to doxorubicin and mitomycin C. Anticancer Res 20: 4319-4322, 2000.
22. Marquies ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin GY, Abel KJ, Weber BL and Chodosh LA: The development pattern of BRCA1 expression implies a role in differentiation of the breast and other tissues. Nat Genet 11: 17-26, 1995.
23. Holt JT, Thompson ME, Szabo C, Robinson-Benion C, Arteaga CL, King MC and Jensen RA: Growth retardation and tumour inhibition by BRCA1. Nat Genet 12: 298-302, 1996.
24. Seery LT, Knowlden JM, Gee JMW, Robertson JFR, Kenny FS, Ellis IO and Nicholson RI: BRCA1 expression levels predict distant metastasis of sporadic breast cancers. Int J Cancer 84: 258-262, 1999.
25. Yang Q, Sakurai T, Mori I, Yoshimura G, Nakamura M, Nakamura Y, Suzuma T, Tamaki T, Umemura T and Kakudo K: Prognositc significance of BRCA1 expression in Japanese sporadic breast cancers. Cancer 92: 54-60, 2001.
26. Thangaraju M, Kaufmann SH and Couch FJ: BRCA1 faclilitates stress-induced apoptosis in breast and ovarian cancer cell lines. J Biol Chem 275: 31869-75, 2000.
27. Lee WY, Jin YT, Chang TW, Lin PW and Su IJ: Immunolocalization of BRCA1 protein in normal breast tissue and sporadic invasive ductal carcinomas: a correlation with other biological parameters. Histopathology 34: 106-112, 1999.
28. Freneaux P, Stoppa-Lyonnet D, Mouret E, kambouchner M, Nicolas A, Zafrani B, Vincent-Salomon A, Fourquet A, Magdelenat H and Sastre-Garau X: Low expression of bcl-2 in BRCA-1 associated breast cancers. Br J Cancer 83: 1318-1322, 2000.