Separation and assay of 14C-labeled glyceryl trinitrate and its metabolites by OPLC coupled with on-line of off-line radioactivity detection

Journal of Planar Chromatography - Modern TLC

Volumn 15, Issue 6, 2002, Pages 404-409

  Klebovich, Imre ^a   Morovján, György ^a   Hazai, István ^b   Mincsovics, Emil ^c  

^a EGIS PHARMACEUTICALS LTD   (Hungary)

^b TEVA PHARMACEUTICALS   (Israel)

^c OPLC NIT Ltd   (Hungary)

Author keywords

Digital autoradiography (DAR); Glyceryl trinitrate; HPLC radioactivity detection (HPLC RD); Hyphenated techniques; Metabolism study; On line OPLC radioactivity detection (OPLC RD); Phosphor imaging bioimaging

Indexed keywords

BIOASSAY; CARDIOLOGY; DISEASES; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES; RADIOACTIVITY; RADIOGRAPHY; THIN LAYER CHROMATOGRAPHY;

ANGINAL ATTACKS;

CHROMATOGRAPHIC ANALYSIS;

ACETONITRILE; CARBON 14; DRUG METABOLITE; ETHER DERIVATIVE; GLYCERYL TRINITRATE; PHOSPHORUS; SILICA GEL;

AUTORADIOGRAPHY; CONTROLLED STUDY; DIGITAL RADIOGRAPHY; DRUG ISOLATION; DRUG STRUCTURE; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; ONLINE SYSTEM; OVERPRESSURED LAYER CHROMATOGRAPHY; PROCESS OPTIMIZATION; RADIATION DETECTION; RADIATION DETECTOR; RADIOCHEMISTRY; RAT; REVIEW; SCINTIGRAPHY; SEPARATION TECHNIQUE;

EID: 0036874502     PISSN: 09334173     EISSN: None     Source Type: Journal    
DOI: 10.1556/JPC.15.2002.6.2     Document Type: Review

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