메뉴 건너뛰기




Volumn 105, Issue 2, 2002, Pages 223-232

A peptide based on an anti-DNA autoantibody downregulates matrix metalloproteinases in murine models of lupus

Author keywords

CDR based peptide; Immunomodulation; Involvement of MMPs in lupus; MMPs in affected kidneys

Indexed keywords

AUTOANTIBODY; DNA ANTIBODY; GELATINASE B; MATRIX METALLOPROTEINASE; PEPTIDE ANTIBODY; STROMELYSIN; THREONYLGLYCYLTYROSYLTYROSYLMETHIONYLGLUTAMINE; UNCLASSIFIED DRUG;

EID: 0036867618     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2002.5279     Document Type: Article
Times cited : (11)

References (41)
  • 1
    • 0001404232 scopus 로고
    • An overview of the pathogenesis of systemic lupus erythematosus
    • (D. J. Wallace, and B. H. Hahn, Eds.),. 5th ed. Williams and Wilkins; Philadelphia
    • Hahn, B. H., An overview of the pathogenesis of systemic lupus erythematosus. In "Dubois' Lupus Erythematosus" (D. J. Wallace, and B. H. Hahn, Eds.),. 5th ed. Williams and Wilkins; Philadelphia,1993.
    • (1993) Dubois' Lupus Erythematosus
    • Hahn, B.H.1
  • 2
    • 0032725836 scopus 로고    scopus 로고
    • Tumor necrosis factor and other cytokines in murine lupus
    • Theofilopoulos, A. N., and Lawson, B. R., Tumor necrosis factor and other cytokines in murine lupus. Ann. Rheum. Dis. 58(Suppl.), 149-155, 1999.
    • (1999) Ann. Rheum. Dis. , vol.58 , Issue.SUPPL. , pp. 149-155
    • Theofilopoulos, A.N.1    Lawson, B.R.2
  • 4
    • 0027484975 scopus 로고
    • The role of the 16/6 idiotype network in the induction and manifestation of systemic lupus erythematosus
    • Waisman, A., Mendelovic, S., Ruiz, J. P., Zinger, H., Meshorer, A., and Mozes, E., The role of the 16/6 idiotype network in the induction and manifestation of systemic lupus erythematosus. Int. Immunol. 5,1293-1300, 1993.
    • (1993) Int. Immunol. , vol.5 , pp. 1293-1300
    • Waisman, A.1    Mendelovic, S.2    Ruiz, J.P.3    Zinger, H.4    Meshorer, A.5    Mozes, E.6
  • 6
    • 0030940121 scopus 로고    scopus 로고
    • Modulation of murine systemic lupus erythematosus with peptides based on complementary determining regions of a pathogenic anti-DNA monoclonal antibody
    • Waisman, A., Ruiz, P. J., Israeli, E., Eilat, E., Konen-Waisman, S., Zinger, H., Dayan, M., and Mozes, E., Modulation of murine systemic lupus erythematosus with peptides based on complementary determining regions of a pathogenic anti-DNA monoclonal antibody. Proc. Natl. Acad. Sci. USA 94, 4620-4625, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4620-4625
    • Waisman, A.1    Ruiz, P.J.2    Israeli, E.3    Eilat, E.4    Konen-Waisman, S.5    Zinger, H.6    Dayan, M.7    Mozes, E.8
  • 7
    • 0033863364 scopus 로고    scopus 로고
    • Prevention of systemic lupus erythematosus-like disease in (NZBxNZW)F1 mice by treating with CDR1- and CDR3-based peptides of a pathogenic autoantibody
    • Eilat, E., Zinger, H., Nyska, A., and Mozes, E., Prevention of systemic lupus erythematosus-like disease in (NZBxNZW)F1 mice by treating with CDR1- and CDR3-based peptides of a pathogenic autoantibody. J. Clin. Immunol. 20, 268-278, 2000.
    • (2000) J. Clin. Immunol. , vol.20 , pp. 268-278
    • Eilat, E.1    Zinger, H.2    Nyska, A.3    Mozes, E.4
  • 8
    • 0035970048 scopus 로고    scopus 로고
    • The mechanism by which a peptide based on the complementarity determining region-1 of a pathogenic anti-DNA autoantibody ameliorates experimental SLE
    • Eilat, E., Dayan, M., Zinger, H., and Mozes, E., The mechanism by which a peptide based on the complementarity determining region-1 of a pathogenic anti-DNA autoantibody ameliorates experimental SLE. Proc. Natl. Acad. Sci. USA 98, 1148-1153, 2001.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1148-1153
    • Eilat, E.1    Dayan, M.2    Zinger, H.3    Mozes, E.4
  • 10
    • 0030028043 scopus 로고    scopus 로고
    • Matrix metalloproteinases in immunity
    • Goetzl, E. J., Banda, M. J., and Leppert, D., Matrix metalloproteinases in immunity. J. Immunol. 156, 1-4, 1996.
    • (1996) J. Immunol. , vol.156 , pp. 1-4
    • Goetzl, E.J.1    Banda, M.J.2    Leppert, D.3
  • 11
    • 0031656460 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Structures, evolution and diversification
    • Massova, I., Kotra, L. P., Fridman, R., and Mobashery, S., Matrix metalloproteinases: structures, evolution and diversification. FASEB. J. 12, 1075-1095, 1998.
    • (1998) FASEB. J. , vol.12 , pp. 1075-1095
    • Massova, I.1    Kotra, L.P.2    Fridman, R.3    Mobashery, S.4
  • 12
    • 0030405381 scopus 로고    scopus 로고
    • The role of metalloproteinases and their inhibitors in hematological disorders
    • Guedez, L., Lim, M. S., and Stetler-Stevenson, W. G., The role of metalloproteinases and their inhibitors in hematological disorders. Crit. Rev. Oncog. 7, 205-225, 1996.
    • (1996) Crit. Rev. Oncog. , vol.7 , pp. 205-225
    • Guedez, L.1    Lim, M.S.2    Stetler-Stevenson, W.G.3
  • 14
    • 0027944171 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteinases
    • Gijbels, K., Galardy, R. E., and Steinman, L., Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteinases. J. Clin. Invest. 94, 2177-2189, 1994.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2177-2189
    • Gijbels, K.1    Galardy, R.E.2    Steinman, L.3
  • 15
    • 0032926067 scopus 로고    scopus 로고
    • Circulating levels of matrix metalloproteinases MMP-3 and MMP-1, tissue inhibitor of metalloproteinases 1 (TIMP-1), and MMP-1/TIMP-1 complex in rheumatic disease. Correlation with clinical activity of rheumatoid arthritis versus other surrogate markers
    • Keyszer, G., Lambiri, I., Nagel, R., Keysser, C., Keysser, M., Gromnica-Ihle, E., Franz, J., Burmester, G. R., and Jung, K., Circulating levels of matrix metalloproteinases MMP-3 and MMP-1, tissue inhibitor of metalloproteinases 1 (TIMP-1), and MMP-1/TIMP-1 complex in rheumatic disease. Correlation with clinical activity of rheumatoid arthritis versus other surrogate markers. J. Rheumatol. 26, 251-258, 1999.
    • (1999) J. Rheumatol. , vol.26 , pp. 251-258
    • Keyszer, G.1    Lambiri, I.2    Nagel, R.3    Keysser, C.4    Keysser, M.5    Gromnica-Ihle, E.6    Franz, J.7    Burmester, G.R.8    Jung, K.9
  • 17
    • 0032479967 scopus 로고    scopus 로고
    • Gelatinase B-deficient mice are resistant to experimental bullous Pemphigoid
    • Liu, Z., Shipley, J. M., Vu, T. H., Zhou, X., Diaz, L. A., Werb, Z., and Senior, R. M., Gelatinase B-deficient mice are resistant to experimental bullous Pemphigoid. J. Exp. Med. 188, 475-482, 1998.
    • (1998) J. Exp. Med. , vol.188 , pp. 475-482
    • Liu, Z.1    Shipley, J.M.2    Vu, T.H.3    Zhou, X.4    Diaz, L.A.5    Werb, Z.6    Senior, R.M.7
  • 19
    • 0031656122 scopus 로고    scopus 로고
    • Serum matrix metalloproteinase-3 and fibrin degradation product levels correlate with clinical disease activity in rheumatoid arthritis
    • Ichikawa, Y., Yamada, C., Horiki, T., Hoshina, Y., and Uchiyama, M., Serum matrix metalloproteinase-3 and fibrin degradation product levels correlate with clinical disease activity in rheumatoid arthritis. Clin. Exp. Rheumatol. 16, 533-540, 1998.
    • (1998) Clin. Exp. Rheumatol. , vol.16 , pp. 533-540
    • Ichikawa, Y.1    Yamada, C.2    Horiki, T.3    Hoshina, Y.4    Uchiyama, M.5
  • 20
    • 0032942539 scopus 로고    scopus 로고
    • Increased serum stromelysin-1 levels in systemic lupus erythematosus: Lack of correlation with disease activity
    • Zucker, S., Increased serum stromelysin-1 levels in systemic lupus erythematosus: Lack of correlation with disease activity. J. Rheumatol. 26, 78-80, 1999.
    • (1999) J. Rheumatol. , vol.26 , pp. 78-80
    • Zucker, S.1
  • 22
    • 0029122966 scopus 로고
    • Inhibition of cartilage and bone destruction in adjuvant arthritis in the rat by a matrix metalloproteinase inhibitor
    • Conway, J. G., Wakefield, J. A., Brown, R. H., Marron, B. E., Sekut, L., Clark, R. L., McGeechan, G. M., and Connolly, K. M., Inhibition of cartilage and bone destruction in adjuvant arthritis in the rat by a matrix metalloproteinase inhibitor. J. Exp. Med. 182, 449-457, 1995.
    • (1995) J. Exp. Med. , vol.182 , pp. 449-457
    • Conway, J.G.1    Wakefield, J.A.2    Brown, R.H.3    Marron, B.E.4    Sekut, L.5    Clark, R.L.6    McGeechan, G.M.7    Connolly, K.M.8
  • 23
    • 0028939618 scopus 로고
    • The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment
    • Waisman, A., Shoenfeld, Y., Blank, M., Ruiz, P. J., and Mozes, E., The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment. Int. Immunol. 7, 689-696, 1995.
    • (1995) Int. Immunol. , vol.7 , pp. 689-696
    • Waisman, A.1    Shoenfeld, Y.2    Blank, M.3    Ruiz, P.J.4    Mozes, E.5
  • 25
    • 0026486811 scopus 로고
    • In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences
    • Schnolzer, M., Alewood, P. F., and Kent, S. B. H., In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences. Int. J. Pept. Protein Res. 40, 180-193, 1992.
    • (1992) Int. J. Pept. Protein Res. , vol.40 , pp. 180-193
    • Schnolzer, M.1    Alewood, P.F.2    Kent, S.B.H.3
  • 26
    • 0027239673 scopus 로고
    • Gene expression of metalloproteinases and their inhibitor in renal tissue of New Zealand Black/White F1 mice
    • Nakamura, T., Ebihara, I., Osada, S., Takahashi, T., Yamamoto, M., Tomino, Y., and Koide, H., Gene expression of metalloproteinases and their inhibitor in renal tissue of New Zealand Black/White F1 mice. Clin. Sci. 85, 295-301, 1993.
    • (1993) Clin. Sci. , vol.85 , pp. 295-301
    • Nakamura, T.1    Ebihara, I.2    Osada, S.3    Takahashi, T.4    Yamamoto, M.5    Tomino, Y.6    Koide, H.7
  • 27
    • 0033536007 scopus 로고    scopus 로고
    • Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response
    • Wang, M., Qin, X., Mudgett, J. S., Ferguson, T. A., Senior, R. M., and Welgus, H. G., Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response. Proc. Natl. Acad. Sci. USA 96, 6885-6889, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6885-6889
    • Wang, M.1    Qin, X.2    Mudgett, J.S.3    Ferguson, T.A.4    Senior, R.M.5    Welgus, H.G.6
  • 28
    • 0032521238 scopus 로고    scopus 로고
    • Stromelysin-1 (MMP-3)-independent gelatinase expression and activation in mice
    • Lijnen, H. R., Silence, J., Van Hoef, B., and Collen, D., Stromelysin-1 (MMP-3)-independent gelatinase expression and activation in mice. Blood 91; 2045-2053, 1998.
    • (1998) Blood , vol.91 , pp. 2045-2053
    • Lijnen, H.R.1    Silence, J.2    Van Hoef, B.3    Collen, D.4
  • 29
    • 0026660964 scopus 로고
    • Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9
    • Ogata, Y., Enghild, J. J., and Nagase, H., Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9. J. Biol. Chem. 267, 3581-3584, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3581-3584
    • Ogata, Y.1    Enghild, J.J.2    Nagase, H.3
  • 30
    • 0030030166 scopus 로고    scopus 로고
    • Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase-9 with enhanced expression in a model of membranous nephropathy
    • McMillan, J. I., Riordan, J. W., Couser, W. G., Polock, A. S., and Lovett, D., Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase-9 with enhanced expression in a model of membranous nephropathy. J. Clin. Invest. 97, 1094-1101, 1996.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1094-1101
    • McMillan, J.I.1    Riordan, J.W.2    Couser, W.G.3    Polock, A.S.4    Lovett, D.5
  • 31
    • 0026637020 scopus 로고
    • Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex mediated glomerulonephritis
    • Lovett, D. H., Johnson, R. J., Marti, H. P., Martin, J., Davis, M., and Couser, W. G., Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex mediated glomerulonephritis. Am. J. Pathol. 141, 85-98, 1992.
    • (1992) Am. J. Pathol. , vol.141 , pp. 85-98
    • Lovett, D.H.1    Johnson, R.J.2    Marti, H.P.3    Martin, J.4    Davis, M.5    Couser, W.G.6
  • 32
    • 0014286368 scopus 로고
    • Glomerular basement membrane in immunologic glomerulonephritis
    • Hawkins, D., and Cochrane, C. G., Glomerular basement membrane in immunologic glomerulonephritis. Immunology 14, 665-681, 1968.
    • (1968) Immunology , vol.14 , pp. 665-681
    • Hawkins, D.1    Cochrane, C.G.2
  • 34
    • 0026442957 scopus 로고
    • Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders
    • Gijbels, K., Masure, S., Carton, H., and Opdenakker, G., Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J. Neuroimmunol. 41, 29-34, 1992.
    • (1992) J. Neuroimmunol. , vol.41 , pp. 29-34
    • Gijbels, K.1    Masure, S.2    Carton, H.3    Opdenakker, G.4
  • 35
    • 0028005697 scopus 로고
    • Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological disease
    • Paemen, L., Olsson, T., Soderstrom, M., Van Damme, J., and Opdenakker, G., Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological disease. Eur. J. Neurol.. 1, 55-63, 1994.
    • (1994) Eur. J. Neurol. , vol.1 , pp. 55-63
    • Paemen, L.1    Olsson, T.2    Soderstrom, M.3    Van Damme, J.4    Opdenakker, G.5
  • 36
    • 0028900052 scopus 로고
    • Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts
    • Miltenburg, A. M., Lacraz, S., Welgus, H. G., and Dayer, J. M., Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts. J. Immunol. 154, 2655-2667, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 2655-2667
    • Miltenburg, A.M.1    Lacraz, S.2    Welgus, H.G.3    Dayer, J.M.4
  • 37
    • 0034096943 scopus 로고    scopus 로고
    • Th2 cell membrane factors in association with IL-4 enhance matrix metalloproteinase-1 (MMP-1) while decreasing MMP-9 production by granulocyte-macrophage colony-stimulating factor-differentiated human monocytes
    • Chizzolini, C., Rezzonico, R., De Luca, C., Burger, D., and Dayer, J-M., Th2 cell membrane factors in association with IL-4 enhance matrix metalloproteinase-1 (MMP-1) while decreasing MMP-9 production by granulocyte-macrophage colony-stimulating factor-differentiated human monocytes. J. Immunol. 164, 5952-5960, 2000.
    • (2000) J. Immunol. , vol.164 , pp. 5952-5960
    • Chizzolini, C.1    Rezzonico, R.2    De Luca, C.3    Burger, D.4    Dayer, J.-M.5
  • 39
    • 0031569093 scopus 로고    scopus 로고
    • Kinetics of cytokine production in experimental systemic lupus erythematosus: Involvement of T helper cell 1/T helper cell 2-type cytokines in disease
    • Segal, R., Bermas, B. L., Dayan, M., Kalush, F., Shearer, G. M., and Mozes, E., Kinetics of cytokine production in experimental systemic lupus erythematosus: Involvement of T helper cell 1/T helper cell 2-type cytokines in disease. J. Immunol. 158, 3009-3016, 1997.
    • (1997) J. Immunol. , vol.158 , pp. 3009-3016
    • Segal, R.1    Bermas, B.L.2    Dayan, M.3    Kalush, F.4    Shearer, G.M.5    Mozes, E.6
  • 40
    • 0030292766 scopus 로고    scopus 로고
    • TNF-α and IL-1β selectively induce expression of 92-kDa gelatinase by human macrophages
    • Saren, P., Welgus, H. G., and Kovanen, P. T., TNF-α and IL-1β selectively induce expression of 92-kDa gelatinase by human macrophages. J. Immunol. 157, 4159-4165, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 4159-4165
    • Saren, P.1    Welgus, H.G.2    Kovanen, P.T.3
  • 41
    • 0025149103 scopus 로고
    • Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinase-1 in rheumatoid synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression
    • MacNaul, K. L., Chartrain, N., Lark, M., Tocci, M. J., and Hutchinson, N. I., Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinase-1 in rheumatoid synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression. J. Biol. Chem. 265, 17238-17245, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17238-17245
    • MacNaul, K.L.1    Chartrain, N.2    Lark, M.3    Tocci, M.J.4    Hutchinson, N.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.