Diagnosis and treatment of ejaculatory dysfunction

Urologic Clinics of North America

Volumn 29, Issue 4, 2002, Pages 939-948

  Schuster, Timothy G ^a   Ohl, Dana A ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; BROMPHENIRAMINE; CHLORPHENIRAMINE; CLOMIPRAMINE; DESIPRAMINE; DEXAMPHETAMINE; EPHEDRINE; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; MIDODRINE; PAROXETINE; PHENOXYBENZAMINE; PHENYLEPHRINE; PHENYLPROPANOLAMINE; PLACEBO; PSEUDOEPHEDRINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ANXIETY; DRUG EFFECT; EJACULATION DISORDER; GASTROINTESTINAL SYMPTOM; HEADACHE; HEART PALPITATION; HUMAN; HYPERTENSION; PNEUMONIA; PREMATURE EJACULATION; PRIORITY JOURNAL; PSYCHOTHERAPY; REVIEW; SEX THERAPY;

EJACULATION; HUMANS; INFERTILITY, MALE; MALE;

EID: 0036865849     PISSN: 00940143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0094-0143(02)00080-0     Document Type: Review

References (87)

1. Maizels M. Normal and anomalous development of the urinary tract. In: Walsh PC, Retik AB, Vaughan EDJ, Wein AJ, editors. Campbell's Urology, Vol. 2. 7th Edition. Philadelphia: W.B. Saunders; 1998. p. 1545-600.
2. Herberg LJ. A hypothalamic mechanism causing seminal ejaculation. Nature 1963;198:219-20.
3. Thomas Jr AJ. Ejaculatory dysfunction. Fertil Steril 1983;39(4):445-54.
4. Kimura Y, Kisaki N, Sakurada S, et al. On the brain monoaminergic systems relating to ejaculation. I. Brain dopamine and ejaculation. Andrologia 1976;8(4):313-20.
5. Kimura Y, Kisaki N, Sakurada S, et al. On the brain monoaminergic systems relating to ejaculation. II. Brain serotonin and ejaculation. Andrologia 1977;9(1):50-4.
6. Gil-Vernet Jr JM, Alvarez-Vijande R, Gil-Vernet A, et al. Ejaculation in men: A dynamic endorectal ultrasonographical study. Br J Urol 1994;73(4):442-8.
7. Mitsuya H, Asai J, Suyama K, et al. Application of x-ray cinematography in urology. I. Mechanism of ejaculation. J Urol 1960;83(1):86-92.
8. Gerstenberg TC, Levin RJ, Wagner G. Erection and ejaculation in man: Assessment of the electromyographic activity of the bulbocavernosus and ischiocavernosus muscles. Br J Urol 1990;65(4):395-402.
9. Bohlen D, Hugonnet CL, Mills RD, et al. Five meters of H(2)O: The pressure at the urinary bladder neck during human ejaculation. Prostate 2000;44(4):339-41.
10. Tauber PF, Zaneveld LJ, Propping D, et al. Components of human split ejaculates. I. Spermatozoa, fructose, immunoglobulins, albumin, lactoferrin, transferrin and other plasma proteins. J Reprod Fertil 1975;43(2):249-67.
11. Tauber PF, Zaneveld LJ, Propping D, et al. Components of human split ejaculates. II. Enzymes and proteinase inhibitors. J Reprod Fertil 1976;46(1):165-71.
12. Nguyen HT, Etzell J, Turek PJ. Normal human ejaculatory duct anatomy: A study of cadaveric and surgical specimens. J Urol 1996;155(5):1639-42.
13. Jarow JP. Seminal vesicle aspiration in the management of patients with ejaculatory duct obstruction. J Urol 1994;152(3):899-901.
14. Master VA, Turek PJ. Ejaculatory physiology and dysfunction. Urol Clin North Am 2001;28(2):363-75.
15. Munkelwitz R, Krasnokutsky S, Lie J, et al. Current perspectives on hematospermia: A review. J Androl 1997;18(1):6-14.
16. Donohue RE, Fauver HE. Unilateral absence of the vas deferens: A useful clinical sign. JAMA 1989;261(8):1180-2.
17. Schlegel PN, Shin D, Goldstein M. Urogenital anomalies in men with congenital absence of the vas deferens. J Urol 1996;155(5):1644-8.
18. Anguiano A, Oates RD, Amos JA, et al. Congenital bilateral absence of the vas deferens: A primarily genital form of cystic fibrosis. JAMA 1992;267(13):1794-7.
19. Hendry WF, Pryor JP. Mullerian duct (prostatic utricle) cyst: Diagnosis and treatment in subfertile males. Br J Urol 1992;69(1):79-82.
20. Pryor JP, Hendry WF. Ejaculatory duct obstruction in subfertile males: Analysis of 87 patients. Fertil Steril 1991;56(4):725-30.
21. Vicente J, del Portillo L, Pomerol MM. Endoscopic surgery in distal obstruction of the ejaculatory ducts. Eur Urol 1983;9(6):338-40.
22. Abrahams JI, Solish GI, Boorjian P, et al. The surgical correction of retrograde ejaculation. J Urol 1975;114(6):888-90.
23. Middleton RG, Urry RL. The Young-Dees operation for the correction of retrograde ejaculation. J Urol 1986;136(6):1208-9.
24. Ohl DA, Bennett CJ, McCabe M, et al. Predictors of success in electroejaculation of spinal cord injured men. J Urol 1989;142(6):1483-6.
25. Dunsmuir WD, Emberton M. There is significant sexual dysfunction following TURP. Br J Urol 1996;77(161, Suppl 1):39-40.
26. Hedlund H, Ek A. Ejaculation and sexual function after endoscopic bladder neck incision. Br J Urol 1985;57(2):164-7.
27. Thorpe AC, Cleary R, Coles J, et al. Written consent about sexual function in men undergoing transurethral prostatectomy. Br J Urol 1994;74(4):479-84.
28. Ochsner MG, Burns E, Henry HH. Incidence of retrograde ejaculation following bladder neck revision as a child. J Urol 1970;104(4):596-7.
29. Geboes K, Steeno O, De Moor P. Primary anejaculation: Diagnosis and therapy. Fertil Steril 1975;26(10):1018-20.
30. Shull GR, Sprenkle DH. Retarded ejaculation reconceptualization and implications for treatment. J Sex Marital Ther 1980;6(4):234-46.
31. Hovav Y, Dan-Goor M, Yaffe H, et al. Nocturnal sperm emission in men with psychogenic anejaculation. Fertil Steril 1999;72(2):364-5.
32. Hovav Y, Kafka I, Horenstein E, et al. Prostatic massage as a method for obtaining spermatozoa in men with psychogenic anejaculation. Fertil Steril 2000;74(1):184-5.
33. Okada H, Fujisawa M, Koshida M, et al. Ampullary, seminal vesicular, and prostatic massage for obtaining spermatozoa from patients with anejaculation. Fertil Steril 2001;75(6):1236-7.
34. Wheeler Jr JS, Walter JS, Culkin DJ, et al. Idiopathic anejaculation treated by vibratory stimulation. Fertil Steril 1988;50(2):377-9.
35. Denil J, Kupker W, Al-Hasani S, et al. Successful combination of transrectal electroejaculation and intracytoplasmic sperm injection in the treatment of anejaculation. Hum Reprod 1996;11(6):1247-9.
36. Stewart DE, Ohl DA. Idiopathic anejaculation treated by electroejaculation. Int J Psychiatry Med 1989;19(3):263-8.
37. Waldinger MD, Hengeveld MW, Zwinderman AH, et al. Effect of SSRI antidepressants on ejaculation: A double-blind, randomized, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine, and sertraline. J Clin Psychopharmacol 1998;18(4):274-81.
38. Masters W, Johnson V. Premature Ejaculation: Human Sexual Inadequacy. Boston: Little Brown; 1970. p. 92-115.
39. Xin ZC, Chung WS, Choi YD, et al. Penile sensitivity in patients with primary premature ejaculation. J Urol 1996;156(3):979-81.
40. Colpi GM, Fanciullacci F, Beretta G, et al. Evoked sacral potentials in subjects with true premature ejaculation. Andrologia 1986;18(6):583-6.
41. Fanciullacci F, Colpi GM, Beretta G, et al. Cortical evoked potentials in subjects with true premature ejaculation. Andrologia 1988;20(4):326-30.
42. Ozcan C, Ozbek E, Soylu A, et al. Auditory event-related potentials in patients with premature ejaculation. Urology 2001;58(6):1025-9.
43. Berkovitch M, Keresteci AG, Koren G. Efficacy of prilocaine-lidocaine cream in the treatment of premature ejaculation. J Urol 1995;154(4):1360-1.
44. Sahin H, Bircan MK. Re: Efficacy of prilocainelidocaine cream in the treatment of premature ejaculation, J Urol 1996;156(5):1783-4.
45. Shilon M, Paz GF, Homonnai ZT. The use of phenoxybenzamine treatment in premature ejaculation, Fertil Steril 1984;42(4):659-61.
46. Girgis SM, El-Haggar S, El-Hermouzy S. A double-blind trial of clomipramine in premature ejaculation. Andrologia 1982;14(4):364-8.
47. Haensel SM, Rowland DL, Kallan KT. Clomipramine and sexual function in men with premature ejaculation and controls. J Urol 1996;156(4):1310-5.
48. Kim SC, Seo KK. Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculation: A double-blind, placebo-controlled study. J Urol 1998;159(2):425-7.
49. Biri H, Isen K, Sinik Z, et al. Sertraline in the treatment of premature ejaculation: A double-blind placebo controlled study. Int Urol Nephrol 1998;30(5):611-5.
50. Haensel SM, Klem TM, Hop WC, et al. Fluoxetine and premature ejaculation: A double-blind, crossover, placebo-controlled study. J Clin Psychopharmacol 1998;18(1):72-7.
51. Kara H, Aydin S, Yucel M, et al. The efficacy of fluoxetine in the treatment of premature ejaculation: A double-blind placebo-controlled study. J Urol 1996;156(5):1631-2.
52. Waldinger MD, Hengeveld MW, Zwinderman AH. Paroxetine treatment of premature ejaculation: A double-blind, randomized, placebo-controlled study. Am J Psychiatry 1994;151(9):1377-9.
53. Waldinger MD, Hengeveld MW, Zwinderman AH. Ejaculation-retarding properties of paroxetine in patients with primary premature ejaculation: A double-blind, randomized, dose-response study. Br J Urol 1997;79(4):592-5.
54. Kim SW, Paick JS. Short-term analysis of the effects of as needed use of sertraline at 5 PM for the treatment of premature ejaculation. Urology 1999;54(3):544-7.
55. Debruyne FM. Alpha blockers: Are all created equal? Urology 2000;56(5 Suppl):20-2.
56. Hendry WF. Disorders of ejaculation: Congenital, acquired and functional. Br J Urol 1998;82(3):331-41.
57. Weinstein MH, Machleder HI: Sexual function after aorto-lliac surgery. Ann Surg 1975;181(6):787-90.
58. Kedia KR, Markland C, Fraley EE. Sexual function after high retroperitoneal lymphadenectomy. Urol Clin North Am 1977;4(3):523-8.
59. Donohue JP, Foster RS, Rowland RG, et al. Nervesparing retroperitoneal lymphadenectomy with preservation of ejaculation. J Urol 1990;144(2):287-91.
60. Litwiller SE, Frohman EM, Zimmern PE. Multiple sclerosis and the urologist. J Urol 1999;161(3):743-57.
61. Mattson D, Petrie M, Srivastava DK, et al. Multiple sclerosis: Sexual dysfunction and its response to medications. Arch Neurol 1995;52(9):862-8.
62. Zorzon M, Zivadinov R, Monti Bragadin L, et al. Sexual dysfunction in multiple sclerosis: A 2-year follow-up study. J Neurol Sci 2001;187(1-2):1-5.
63. Yki-Jarvinen H. Pathogenesis of non-insulin-dependent diabetes mellitus. Lancet 1994;343:91-5.
64. Dunsmuir WD, Holmes SA. The aetiology and management of erectile, ejaculatory, and fertility problems in men with diabetes mellitus. Diabet Med 1996;13(8):700-8.
65. Sexton WJ, Jarow JP. Effect of diabetes mellitus upon male reproductive function. Urology 1997;49(4):508-13.
66. Griffith ER, Tomko MA, Timms RJ. Sexual function in spinal cord-injured patients: A review. Arch Phys Med Rehabil 1973;54(12):539-43.
67. Kamischke A, Nieschlag E. Treatment of retrograde ejaculation and anejaculation. Hum Reprod Update 1999;5(5):448-74.
68. Crich JP, Jequier AM. Infertility in men with retrograde ejaculation: The action of urine on sperm motility, and a simple method for achieving antegrade ejaculation. Fertil Steril 1978;30(5):572-6.
69. Suominen JJ, Kilkku PP, Taina EJ, et al. Successful treatment of infertility due to retrograde ejaculation by instillation of serum-containing medium into the bladder: A case report. Int J Androl 1991;14(2):87-90.
70. Ohl DA, Menge AC, Sonksen J. Penile vibratory stimulation in spinal cord injured men: Optimized vibration parameters and prognostic factors. Arch Phys Med Rehabil 1996;77(9):903-5.
71. Szasz G, Carpenter C. Clinical observations in vibratory stimulation of the penis of men with spinal cord injury. Arch Sex Behav 1989;18(6):461-74.
72. Sønksen J, Biering-Sorensen F, Kristensen JK. Ejaculation induced by penile vibratory stimulation in men with spinal cord lesion: The importance of the vibratory amplitude. Paraplegia 1994;32(10):6-60.
73. Bennett CJ, Ayers JW, Randolph Jr JF, et al. Electroejaculation of paraplegic males followed by pregnancies. Fertil Steril 1987;48(6):1070-2.
74. Ohl DA, Denil J, Bennett CJ, et al. Electroejaculation following retroperitoneal lymphadenectomy. J Urol 1991;145(5):980-3.
75. Gerig NE, Meacham RB, Ohl DA. Use of electroejaculation in the treatment of ejaculatory failure secondary to diabetes mellitus. Urology 1997;49(2):239-42.
76. Brackett NL, Abae M, Padron OF, et al. Treatment by assisted conception of severe male factor infertility due to spinal cord injury or other neurologic impairment. J Assist Reprod Genet 1995;12(3):210-6.
77. Sønksen J, Ohl DA, Wedemeyer G. Sphincteric events during penile vibratory ejaculation and electroejaculation in men with spinal cord injuries. J Urol 2001;165(2):426-9.
78. Belker AM, Sherins RJ, Bustillo M, et al. Pregnancy with microsurgical vas sperm aspiration from a patient with neurologic ejaculatory dysfunction. J Androl 1994;15(Suppl):6S-9S.
79. Brackett NL, Lynne CM, Aballa TC, et al. Sperm motility from the vas deferens of spinal cord injured men is higher than from the ejaculate. J Urol 2000;164(3 Pt 1):712-5.
80. Buch JP, Zorn BH. Evaluation and treatment of infertility in spinal cord injured men through rectal probe electroejaculation. J Urol 1993;149(5 Pt 2):1350-4.
81. Sønksen J, Ohl DA, Giwercman A, et al. Quality of semen obtained by penile vibratory stimulation in men with spinal cord injuries: Observations and predictors. Urology 1996;48(3):453-7.
82. Denil J, Ohl DA, Menge AC, et al. Functional characteristics of sperm obtained by electroejaculation. J Urol 1992;147(1):69-72.
83. Brackett NL, Padron OF, Lynne CM. Semen quality of spinal cord injured men is better when obtained by vibratory stimulation versus electroejaculation. J Urol 1997;157(1):151-7.
84. Ohl DA, Sonksen J, Menge AC, et al. Electroejaculation versus vibratory stimulation in spinal cord injured men: Sperm quality and patient preference. J Urol 1997;157(6):2147-9.
85. Sønksen J, Sommer P, Biering-Sørensen F, et al. Pregnancy after assisted ejaculation procedures in men with spinal cord injury. Arch Phys Med Rehabil 1997;78(10):1059-61.
86. Ohl DA, Wolf LJ, Menge AC, et al. Electroejaculation and assisted reproductive technologies in the treatment of anejaculatory infertility. Fertil Steril 2001;76(6):1249-55.
87. Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med 2000;343(25):1826-32.