Potentiation of carbon tetrachloride hepatotoxicity by pentosan polysulfate in rats

Brazilian Journal of Medical and Biological Research

Volumn 35, Issue 11, 2002, Pages 1339-1346

  Zim, M C A ^a   Silveira, T R ^a   Schwartsmann, G ^a   Cerski, T ^a   Motta, A ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Carbon tetrachloride; Cirrhosis; Fibrogenesis; Hepatic necrosis; Pentosan polysulfate

Indexed keywords

CARBON TETRACHLORIDE; PENTOBARBITAL; PENTOSAN POLYSULFATE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; IN VIVO STUDY; LIVER CIRRHOSIS; LIVER CONGESTION; LIVER FIBROSIS; LIVER MICROSOME; LIVER NECROSIS; MALE; NONHUMAN; RAT; RAT STRAIN; SLEEP TIME; WEIGHT;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0036865437     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2002001100012     Document Type: Article

References (30)

1. Jimenez W, Claria J, Arroyo V & Rodés J (1992). Carbon tetrachloride induced cirrhosis in rats: a useful tool for investigating the pathogenesis of ascites in chronic liver disease. Journal of Gastroenterology and Hepatology, 7: 90-97.
2. Gressner AM (1995). Cytokines and cellular crosstalk involved in the activation of fat-storing cells. Journal of Hepatology, 22 (Suppl 2): 28-36.
3. Dooley S, Delvoux B, Lahme B, Mangasser-Stelphank K & Gressner AM (2000). Modulation of transforming growth factor beta response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts. Hepatology, 31: 1094-1106.
4. Andus T & Holstege A (1995). Role of cytokines in hepatic and hepatobiliary diseases. In: Aggarwal BB & Puri RK (Editors), Human Cytokines: Their Role in Disease and Therapy. 1st edn. Blackwell Sciences, Cambridge, MA, USA, 625-640.
5. Friedman SL (1993). The cellular basis of hepatic fibrosis. New England Journal of Medicine, 328: 1828-1835.
6. Schuppan D, Strobel D & Hahn EG (1998). Hepatic fibrosis - therapeutic strategies. Digestion, 59: 385-390.
7. Strobel D & Hahn EG (1997). Pathogenesis of liver fibrogenesis. Digestion, 58 (Suppl): 37-38.
8. Maffrand JP, Herbert JM, Bernat A, Defreyn G, Delebassee D, Savi P, Pinot JJ & Sampol J (1991). Experimental and clinical pharmacology of pentosan polysulfate. Seminars in Thrombosis and Haemostasis, 17 (Suppl 2): 186-197.
9. Zugmaier G, Lippman ME & Wellstein A (1992). Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from cells and blockage by PPS of tumor growth in animals. Journal of the National Cancer Institute, 84: 716-724.
10. Schwartsmann G, Sprinz E, Kalakun L, Yamagushi N, Sander E, Grivicich I, Koya R & Mans AR (1996). Phase II study of pentosan polysulfate (PPS) in patients with Aids-related Kaposi's sarcoma. Tumori, 82: 360-363.
11. Goldim JR (1995). Pesquisa em Saúde e Direitos dos Animais. Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
12. Rosa H, Parise ER, Parnhos FRL, Braga AL, Freitas ASO, Hidalgo NA & Mor MBL (1991). Controlled production of cirrhosis in the rat liver. Arquivos de Gastroenterologia, 28: 39-43.
13. Kiesel J, Harbauer G, Wenzel E, Pindur G & Bohnerth S (1991). Comparison of the effects of sodium pentosan polysulfate and unfractionated heparin on venous thrombosis; an experimental study in rats. Thrombosis Research, 64: 301-308.
14. Tsukamoto H, Matsuoka M & French SW (1990). Experimental models of hepatic fibrosis: a review. Seminars in Liver Disease, 10: 56-65.
15. Conney AH, Davison C, Gastel R & Burns JJ (1960). Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs. Journal of Pharmacology and Experimental Therapeutics, 130: 1-8.
16. Trivedi P & Mowat AP (1983). Carbon tetrachloride-induced hepatic fibrosis and cirrhosis in the developing rat: an experimental model of cirrhosis in childhood. British Journal of Experimental Pathology, 64: 25-33.
17. Ruwart MJ, Wilkinson KF, Rush BD, Vidmar TJ, Peters KM, Henley KS, Appelman HD, Kim KY, Schuppan D & Hahn EG (1989). The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat. Hepatology, 10: 801-806.
18. 4-induced liver damage. Effects of anti-fibrotic agents. Journal of Hepatology, 16: 282-289.
19. Mion F, Géloën A, Agosto E & Minaire Y (1996). Carbon tetrachloride-induced cirrhosis in rats: influence of the acute effects of the toxin on glucose metabolism. Hepatology, 23: 582-588.
20. Hayasaka A, Koch J, Schuppan D, Maddrey WC & Hahn EG (1991). The serum concentrations of the aminoterminal propeptide of procollagen type III and the hepatic content of mRNA for the alpha 1 chain of procollagen type III in carbon tetrachloride-induced rat liver fibrogenesis. Journal of Hepatology, 13: 328-338.
21. Wellstein A & Lippman ME (1991). Fibroblast growth factors and breast cancer. In: Broder S (Editor), Molecular Foundations of Oncology. Williams and Wilkins, Baltimore, MD, USA, 403-418.
22. Odling B, Dencker L & Tengblad A (1987). Preferential localization of 3H-pentosan polysulfate to the urinary tract in rats. Pharmacology and Toxicology, 61: 162-166.
23. Wasser S, Ho JMS, Ang HK & Tan CEL (1998). Salvia miltiorrhiza reduces experimentally-induced hepatic fibrosis in rats. Journal of Hepatology, 29: 760-771.
24. Flaumenhaft R, Moscatelli D, Saksela O & Rifkin DB (1990). The role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long term stimulation of plasminogen activator production and synthesis. Journal of Cellular Physiology, 140: 75-81.
25. Saksela O, Moscatelli D, Sommer A & Rifkin DB (1988). Endothelial cell-derived heparin sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation. Journal of Cell Biology, 107: 743-751.
26. Ferreira AF, Brandão SLB, Prolla JC, Silva VD, Meurer L, Edelweiss MI, Schwartsmann G & Rigatto M (1999). Fibrose pulmonar induzida por bleomicina intratraqueal em ratos Wistar. Descrição do modelo experimental de síndrome de angústia respiratória do adulto e uso do pentosan polissulfato. Arquivos Médicos, 2: 23-33.
27. Liv J, Sendelbach LE, Parkinson A & Klaassen CD (2000). Endotoxin pretreatment protects against the hepatotoxicity of acetaminophen and carbon tetrachloride: role of cytochrome P450 suppression. Toxicology, 147: 167-176.
28. ElSissi AED, Ernest DL & Sipes GI (1993). Vitamin A potentiation of carbon tetrachloride hepatotoxicity: enhanced lipid peroxidation without enhanced biotransformation. Toxicology and Applied Pharmacology, 119: 289-294.
29. Losser MR & Payen D (1996). Mechanisms of liver damage. Seminars in Liver Disease, 16: 357-367.
30. Mizuoka H, Shikata N, Yang J, Takasu M, Inoue K & Tsubura A (1999). Biphasic effect of colchicine on acute liver injury induced by carbon tetrachloride or by dimethylnitrosamine in mice. Journal of Hepatology, 31: 825-833.