Effects of short-term alendronate treatment on the three-dimensional microstructural, physical, and mechanical properties of dog trabecular bone

Bone

Volumn 31, Issue 5, 2002, Pages 591-597

  Hu, J H ^a   Ding, M ^a   Soballe K ^a   Bechtold, J E ^b   Danielsen, C C ^c   Day, J S ^d   Hvid, Ivan ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b HENNEPIN COUNTY MEDICAL CENTER   (United States)

^c AARHUS UNIVERSITY   (Denmark)

^d ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Alendronate; Bisphosphonate; Dog trabecular bone; Mechanical property; Microcomputed tomography (micro CT) scanning; Microstructural property; Physical property

Indexed keywords

ALENDRONIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BIOMECHANICS; BONE STRUCTURE; CANCELLOUS BONE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DOG; FEMALE; HUMERUS; LUMBAR VERTEBRA; NONHUMAN; TRABECULAR BONE; ANIMAL; BONE DENSITY; COMPARATIVE STUDY; DRUG EFFECT; HISTOLOGY; METHODOLOGY; PHYSIOLOGY; THREE DIMENSIONAL IMAGING;

ALENDRONATE; ANIMALS; BIOMECHANICS; BONE DENSITY; DOGS; FEMALE; HUMERUS; IMAGING, THREE-DIMENSIONAL; LUMBAR VERTEBRAE;

EID: 0036861713     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(02)00870-0     Document Type: Article

References (33)

1. Acito A.J., Kasra M., Lee J.M., Grynpas M.D. Effects of intermittent administration of pamidronate on the mechanical properties of canine cortical and trabecular bone. J Orthop Res. 12:1994;742-746.
2. Bechtold J., Mouzin O., Chen X., Søballe K. Relative effects of alendronate and implant motion on revision implant fixation. J Orthop Res Soc. 47:2001;158.
3. Boivin G.Y., Chavassieux P.M., Santora A.C., Yates J., Meunier P.J. Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women. Bone. 27:2000;687-694.
4. Cecchini M.G., Felix R., Fleisch H., Cooper P.H. Effect of bisphosphonates on proliferation and viability of mouse bone marrow-derived macrophages. J Bone Miner Res. 2:1987;135-142.
5. Ciarelli M.J., Goldstein S.A., Kuhn J.L., Cody D.D., Brown M.B. Evaluation of orthogonal mechanical properties and density of human trabecular bone from the major metaphyseal regions with materials testing and computed tomography. J Orthop Res. 9:1991;674-682.
6. Danielsen C.C., Andreassen T.T. Mechanical properties of rat tail tendon in relation to proximal-distal sampling position and age. J Biomech. 21:1988;207-212.
7. Ding M., Dalstra M., Danielsen C.C., Kabel J., Hvid I., Linde F. Age variations in the properties of human tibial trabecular bone. J Bone Jt Surg. 79:1997;995-1002. [Br].
8. Ding M., Odgaard A., Hvid I. Accuracy of cancellous bone volume fraction measured by micro-CT scanning. J Biomech. 32:1999;323-326.
9. Ding M., Odgaard A., Linde F., Hvid I. Age-related variations in the microstructure of human tibial cancellous bone. J Orthop Res. 20:2002;615-621.
10. Ding M. Age variations in the properties of human tibial trabecular bone and cartilage. Acta Orthop Scand. 292:(Suppl.):2000;1-45.
11. Fischer K., Vikoren T., Ney S., Kovach C., Hasselman C., Shanbhag A. Alendronate therapy increases the mechanical properties of canine trabecular bone. J Orthop Res Soc. 46:2000;12.
12. Fleisch H. Mechanisms of action of the bisphosphonates. Medicina (Buenos Aires). 57:(Suppl. 1):1997;65-75.
13. Gatti D., Adami S. New bisphosphonates in the treatment of bone diseases. Drugs Aging. 15:1999;285-296.
14. Giuliani N., Pedrazzoni M., Negri G., Passeri G., Impicciatore M., Girasole G. Bisphosphonates stimulate formation of osteoblast precursors and mineralized nodules in murine and human bone marrow cultures in vitro and promote early osteoblastogenesis in young and aged mice in vivo. Bone. 22:1998;455-461.
15. Goulet R.W., Goldstein S.A., Ciarelli M.J., Kuhn J.L., Brown M.B., Feldkamp L.A. The relationship between the structural and orthogonal compressive properties of trabecular bone. J Biomech. 27:1994;375-389.
16. Grynpas M.D., Acito A., Dimitriu M., Mertz B.P., Very J.M. Changes in bone mineralization, architecture and mechanical properties due to long-term (1 year) administration of pamidronate (APD) to adult dogs. Osteopor Int. 2:1992;74-81.
17. Hildebrand T., Rüegsegger P. Quantification of bone microarchitecture with the structure model index. Comput Methods Biomech Biomed Engin. 1:1997;15-23.
18. Hildebrand T., Rüegsegger P. A new method for the model-independent assessment of thickness in three-dimensional images. J Microsc. 185:1997;67-75.
19. Ingham E., Fisher J. Biological reactions to wear debris in total joint replacement. Proc Inst Mech Eng [H]. 214:2000;21-37.
20. Kimmel D.B., Jee W.S. A quantitative histologic study of bone turnover in young adult beagles. Anat Rec. 203:1982;31-45.
21. Lafage M.H., Balena R., Battle M.A., Shea M., Seedor J.G., Klein H., Hayes W.C., Rodan G.A. Comparison of alendronate and sodium fluoride effects on cancellous and cortical bone in minipigs. A one-year study. J Clin Invest. 95:1995;2127-2133.
22. Lepola V.T., Hannuniemi R., Kippo K., Lauren L., Jalovaara P., Vaananen H.K. Long-term effects of clodronate on growing rat bone. [published erratum appears in Bone 1996 Aug;19(2):205] Bone. 18:1996;191-196.
23. Linde F., Gothgen C.B., Hvid I., Pongsoipetch B. Mechanical properties of trabecular bone by a non-destructive compression testing approach. Eng Med. 17:1988;23-29.
24. Linde F., Hvid I. The effect of constraint on the mechanical behaviour of trabecular bone specimens. [see comments] J Biomech. 22:1989;485-490.
25. Mashiba T., Hirano T., Turner C.H., Forwood M.R., Johnston C.C., Burr D.B. Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res. 15:2000;613-620. [see comments].
26. Mosekilde L. Age-related changes in vertebral trabecular bone architecture - Assessed by a new method. Bone. 9:1988;247-250.
27. Mueller M., Schilling T., Minne H.W., Ziegler R. A systemic acceleratory phenomenon (SAP) accompanies the regional acceleratory phenomenon (RAP) during healing of a bone defect in the rat. J Bone Miner Res. 6:1991;401-410.
28. Neuman R.E., Logan M.A. The determination of collagen and elastin in tissues. J Biol Chem. 186:1950;549-556.
29. Parfitt A.M. The physiologic and clinical significance of bone histomorphometric data. Recker R.R. Bone Histomorphometry. Techniques and Interpretations. 1983;143-223 CRC, Boca Raton, FL.
30. Peter C.P., Guy J., Shea M., Bagdon W., Kline W.F., Hayes W.C. Long-term safety of the aminobisphosphonate alendronate in adult dogs. I. General safety and biomechanical properties of bone. J Pharmacol Exp Ther. 276:1996;271-276.
31. Rodan G.A. Coupling of bone resorption and formation during bone remodeling. Marcus R. Osteoporosis. 1:1996;290-299 Academic, San Diego, CA.
32. Shanbhag A.S., Hasselman C.T., Rubash H.E. The John Charnley Award. Inhibition of wear debris mediated osteolysis in a canine total hip arthroplasty model. Clin Orthop. 344:1997;33-43.
33. Turner C.H., Cowin S.C., Rho J.Y., Ashman R.B., Rice J.C. The fabric dependence of the orthotropic elastic constants of cancellous bone. J Biomech. 23:1990;549-561.