Nodal CD8 positive cytotoxic T-cell lymphoma: A distinct clinicopathological entity

Modern Pathology

Volumn 15, Issue 11, 2002, Pages 1131-1139

  Mukai, Harumi Y ^a,b   Hasegawa, Yuichi ^a   Kojima, Hiroshi ^a   Okoshi, Yasushi ^a   Takei, Naoko ^a   Yamashita, Yoriko ^b   Nagasawa, Toshiro ^a   Mori, Naoyoshi ^b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cytotoxic T cell; DIC; GD8; HPS

Indexed keywords

ANTIGEN; CD8 ANTIGEN; GRANZYME B; PERFORIN;

ADOLESCENT; AGED; APOPTOSIS; ARTICLE; BONE MARROW; CANCER SURVIVAL; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; HEMOPHAGOCYTIC SYNDROME; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER; LYMPH NODE; MALE; MOLECULE; NATURAL KILLER CELL; NEOPLASM; PATHOLOGY; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; SCHOOL CHILD; T CELL LYMPHOMA;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD3; ANTIGENS, CD8; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; GRANZYMES; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERFERON TYPE II; LYMPH NODES; LYMPHOMA, T-CELL; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; POLY(A)-BINDING PROTEINS; PORE FORMING CYTOTOXIC PROTEINS; PROTEINS; RNA-BINDING PROTEINS; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036861235     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MP.0000036343.61268.64     Document Type: Article

References (44)

1. Anderson P, Nagler-Anderson C, O'Brien C, Levine H, Watkins S, Slayter HS, et al. A monoclonal antibody reactive with a 15-kDa cytoplasmic granule associated protein defines a subpopulations of CD8+ T lymphocytes. J Immunol 1990;144:574-82.
2. Garcia-Sanz JA, MacDonald HR, Jenne DE, Tschopp J, Nabholz M. Cell specificity of granzyme gene expression. J Immunol 1990;145:3111-8.
3. Lichtenheld MG, Olsen KJ, Lu P, Lowrey DM, Hameed A, Hengartner H, Podack ER. Structure and function of human perforin. Nature 1988;335:448-51.
4. Liu CC, Walsh CM, Young JDE. Perforin: Structure and function. Immunol Today 1995;16:195-201.
5. de Bruin PC, Kummer JA, van der Valk P, van Heerde P, Kluin PM, Willemze R, et al. Granzyme B-expressing peripheral T-cell lymphomas: Neoplastic equivalents of activated T cells with preference for mucosa-associated lymphoid tissue localization. Blood 1994;84:3785-91.
6. Felgar RE, Macon WR, Kinney MC, Roberts S, Pasha T, Salhany KE. TIA-1 expression in lymphoid neoplasms. Identification of subsets with cytotoxic T lymphocyte or natural killer cell differentiation. Am J Pathol 1997;150:1893-900.
7. Chan WC, Link S, Mawle A, Check I, Brynes RK, Winton EF. Heterogeneity of large granular lymphocyte proliferations: Delineation of two major subtypes. Blood 1986;68:1142-53.
8. Macon WR, Williams ME, Greer JP, Hammer RD, Glick AD, Collins RD, et al. Natural killer-like T-cell lymphomas: Aggressive lymphomas of T-large granular lymphocytes. Blood 1986;87:1474-83.
9. Suzumiya J, Takeshita M, Kimura N, Kikuchi M, Uchida T, Hisano S, et al. Expression of adult and fetal natural killer cell markers in sinonasal lymphomas. Blood 1994;83:2255-60.
10. Emile JF, Boulland ML, Haioun C, Kanavaros P, Petrella T, Delfau-Larue MH, et al. CD5-/CD56+ T-cell receptor silent peripheral T-cell lymphomas are natural killer cell lymphomas. Blood 1996;87:1466-73.
11. Jaffe ES, Chan JKC, Su IJ, Frizzera G, Mori S, Feller AC, et al. Report of the workshop on nasal and related extranodal angiocentric T/natural killer cell lymphomas. Am J Surg Pathol 1996;20:103-11.
12. Mori N, Yatabe Y, Oka K, Kinoshita T, Kobayashi T, Ono T, et al. Expression of perforin in nasal lymphoma. Am J Pathol 1996;149:699-705.
13. Chan JKC, Sin VC, Wong KF, Ng CS, Tsang WY, Chan CH, et al. Nonnasal lymphoma expressing the natural killer cell marker CD56: A clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. Blood 1997;89:4501-13.
14. Cooke CB, Krenacs L, Stetler-Stevenson M, Greiner TC, Raffeld M, Kingma DW, et al. Hepatosplenic T-cell lymphoma: A distinct clinicopathologic entity of cytotoxic T-cell origin. Blood 1996;88:4265-74.
15. Salhany KE, Feldman M, Kahn MJ, Perrit D, Schretzenmair RD, Wilson DM, et al. Hepatosplenic gamma delta T-cell lymphoma: Ultrastructural, immunophenotypic, and functional evidence for cytotoxic T lymphocyte differentiation. Hum Pathol 1997;28:674-85.
16. Kumar S, Krenacs L, Raffeld M, Jaffe ES. Subcutaneous panniculitis-like T-cell lymphoma is a tumor of cytotoxic T lymphocytes [abstract]. Mod Pathol 1997;10:129A.
17. Salhany KE, Macon WR, Choi JK, Elenitsas R, Lessin SR, Felgar RE, et al. Subcutaneous panniculitis-like T-cell lymphoma: Clinicopathologic, immunophenotypic, and genotype analysis of alpha/beta and gamma/delta subtypes. Am J Surg Pathol 1998;22:881-93.
18. Foss HD, Anagnostopoulos I, Araujo I, Assaf I, Demel G, Kummer JA, et al. Anaplastic large cell lymphomas of T-cell and null-cell phenotype express cytotoxic molecules. Blood 1996;88:4005-11.
19. Krenacs L, Wellmann A, Sorbara L, Himmelmann AW, Bagdi E, Jaffe ES, et al. Cytotoxic cell antigen expression in anaplastic large cell lymphomas of T- and null-cell type and Hodgkin's disease: Evidence for distinct cellular origin. Blood 1997;89:980-9.
20. Kagi D, Ledermann B, Burki K, Zinkernagel RM, Hengartner H. Lymphocyte-mediated cytotoxicity in vitro and in vivo: Mechanisms and significance. Immunol Rev 1995;146:95-115.
21. Berke G. The CTCL's kiss of death. Cell 1995;81:9-12.
22. Smyth MJ, Trapani JA. Granzymes: Exogenous proteinases that induce target cell apoptosis. Immunol Today 1995;16:202-6.
23. Stalder T, Hahn S, Erb P. Fas antigen is the major target molecule for CD4+ T-cell-mediated cytotoxicity. J Immunol 1994;152:1127-33.
24. Tian Q, Streuli M, Saito H, Schlossman SF, Anderson P. A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells. Cell 1991;67:629-39.
25. Darmon AJ, Nicholson DW, Bleackley RC. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 1995;377:446-8.
26. Froelich CJ, Dixit VN, Yang X. Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases. Immunol Today 1998;19:30-6.
27. Lanier LL, Spits H, Phillips JH. The developmental relationship between NK cells and T cells. Immunol Today 1992;13:392-4.
28. Griffiths GM, Mueller C. Expression of perforin and granzymes in vivo: Potential diagnostic markers for activated cytotoxic cells. Immunol Today 1991;12:412-9.
29. Salcedo TW, Azzoni L, Wolf SF, Perussia B. Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J Immunol 1993;151:2511-20.
30. Koizumi H, Liu CC, Zheng LM, Joag SV, Bayne NK, Holoshitz J, et al. Expression of perforin and serine-esterases by human γ/δ T cells. J Exp Med 1991;173:499-502.
31. Medley QG, Kedersha N, O'Brien S, Tian Q, Schlossman SF, Streuli M, et al. Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition. Proc Natl Acad Sci USA 1996;93:685-9.
32. Hahn S, Gehri R, Erb P. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol Rev 1995;146:57-79.
33. Yamashita Y, Yatabe Y, Tsuzuki T, Nakayama A, Hasegawa Y, Kojima H, et al. Perforin and granzyme expression in cytotoxic T-cell lymphomas. Mod Pathol 1998;11:313-23.
34. Chang JKC, Chen Y, Shibata D, Weiss L. Description of an in situ Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues. Diagn Mol Pathol 1990;1:246-55.
35. Lay J-D, Tsao C-J, Chen J-Y, Kaden ME, Su IJ. Upregulation of tumor necrosis factor-α gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome. J Clin Invest 1997;100:1969-79.
36. Montalban C, Obeso G, Gallego A, Castrillo JM, Bellas C, Rivas C. Peripheral T-cell lymphoma: A clinicopathological study of 41 cases and evaluation of the prognostic significance of the updated Kiel classification. Histopathology 1993;22:303-10.
37. Chan JKC, Ng CS, Lau WH, Lo STH. Most nasal/nasopharyngeal lymphomas are peripheral T-cell neoplasms. Am J Surg Pathol 1987;11:418-29.
38. Phillips JS, Hori T, Nagler A, Bhat N, Spitz H, Lanier LL. Ontogeny of human natural killer (NK) cells: Fetal NK cells mediate cytolytic function and express cytoplasmic CD3 proteins. J Exp Med 1992;175:1055-66.
39. Kagami Y, Suzuki R, Taji H, Yatabe Y, Takeuchi T, Maeda S, et al. Nodal cytotoxic lymphoma spectrum. A clinicopathologic study of 66 patients. Am J Surg Pathol 1999;23:1184-200.
40. Boulland M-L, Kanavaros P, Wechsler J, Casiraghi O, Gaulard P. Cytotoxic protein expression in natural killer cell lymphomas and in αβ and γδ peripheral T-cell lymphomas. J Pathol 1997;183:432-9.
41. Yamashita Y, Nakamura S, Kagami Y, Hasegawa Y, Kojima H, Nagasawa T, et al. Lennert's lymphoma. A variant of cytotoxic T-cell lymphoma? Am J Surg Pathol 2000;24:1627-33.
42. Kumar S, Krenacs L, Medeiros J, Elenitoba-Johnson KSJ, Griner TC, Sorbara L, et al. Subcutaneous panniculitic T-cell lymphoma is a tumor of cytotoxic T lymphocytes. Hum Pathol 1998;29:397-403.
43. Kagami Y, Sobue R, Ito N, Yatabe Y, Taji H, Suzuki R, et al. Cytotoxic large T-cell lymphoma with fulminant clinical course, CD8+ and CD56- phenotype, and its relation to Epstein-Barr virus: A report of two cases. Int J Hematol 1999;70:105-111.
44. Teruya-Feldstein J, Setsuda J, Yao Xu, Kingma DW, Straus S, Tosato G, et al. MIP-la expression in tissues from patients with hemophagocytic syndrome. Lab Invest 1999;79:1583-1590.