Development of a safe and scalable amine-to-nitrone oxidation: A key step in the synthesis of R107500

Organic Process Research and Development

Volumn 6, Issue 6, 2002, Pages 911-914

  Stappers, Fred ^a   Broeckx, Rudy ^a   Leurs, Stef ^a   Den Bergh, Leo Van ^a   Agten, Jos ^a   Lambrechts, Annemie ^a   Van den Heuvel, Dirk ^a   De Smaele, Dirk ^a  

^a Janssen Pharmaceutica   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ISOXAZOLIDINE DERIVATIVE; NITRONE; R 107500; UNCLASSIFIED DRUG;

CHIRALITY; COLUMN CHROMATOGRAPHY; CONFERENCE PAPER; CYCLOADDITION; DECOMPOSITION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG PURIFICATION; DRUG SYNTHESIS; OXIDATION; REPRODUCIBILITY; SAFETY; SCALE UP;

EID: 0036859486     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op0200569     Document Type: Conference Paper

References (11)

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