Mucolytic agents for acute respiratory tract infections in infants: A pharmaco-epidemiological problem?;Fluidifiants bronchiques dans les infections respiratoires aiguës du nourrisson: Un problème pharmacoépidémiologique?

Archives de Pediatrie

Volumn 9, Issue 11, 2002, Pages 1128-1136

  Chalumeau, Martin ^a,b   Cheron G ^c   Assathiany, R ^d   Moulin, F ^e   Bavoux, F ^e   Breart G ^b   Pons, G ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSERM   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d AREPEGE   (France)

^e Grp Hosp Cochin S Vincent de Paul ^*  (France)

Author keywords

Adverse effects; Bronchial diseases; Cough; Infant; Mucolytic agents; Pharmacoepidemiology

Indexed keywords

ACETYLCYSTEINE; BRONKOCOD; CARBOCISTEINE; CARBOCISTEINE GNR; MUCOLATOR; MUCOLYTIC AGENT;

ARTICLE; BRONCHITIS; CONTROLLED STUDY; COUGHING; DOSE CALCULATION; DOSE RESPONSE; DRUG EFFICACY; DRUG OVERDOSE; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; FINANCIAL MANAGEMENT; HUMAN; LUNG CONGESTION; MAJOR CLINICAL STUDY; PEDIATRICIAN; PHARMACOEPIDEMIOLOGY; PRESCRIPTION; PROSPECTIVE STUDY; RESPIRATORY TRACT INFECTION; RHINOPHARYNGITIS; SIDE EFFECT; TREATMENT INDICATION;

ACETYLCYSTEINE; CARBOCYSTEINE; EXPECTORANTS; FEMALE; FRANCE; HEALTH CARE SURVEYS; HUMANS; INFANT; INFANT, NEWBORN; MALE; PHYSICIAN'S PRACTICE PATTERNS; PROSPECTIVE STUDIES;

EID: 0036858416     PISSN: 0929693X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0929-693X(02)00091-X     Document Type: Article

References (55)

1. Duijvestijn YC, Gerristen J, Brand PL. Acetylcysteïne bij kinderen met longaandoeningen voorgeschreven door eenderde van de huisarstsen; geen onderbouwing in de literatuur. Ned Tijdschr Geneesskd 1997;141:826-30.
2. Chalumeau M, Tréluyer JM, Salanave B, Assathiany R, Chéron G, Crocheton N, et al. Off label and unlicensed drug use among French office-based paediatricians. Arch Dis Child 2000;83:502-5.
3. Bricks LF, Leone C. Utilizaçao de medicamentos por crianças atendidas em creches. Rev Saude Publica 1996;30:527-35.
4. Cazzato T, Pandolfi C, Campi R, Bonati M. Drug prescribing in out-patient children in Southern Italy. Eur J Clin Pharmacol 2001;57:611-6.
5. Gol Valles V, Madridejos Mora R. Descriptive study of the use of drugs in Primary Care paediatricians. Farm Clin 1997;14:642-9.
6. Havez R, Degand P, Roussel P, Randoux A. Mode d'action biochimique des dérivés de la cystéine sur le mucus bronchique. Poumon Cœur 1970;26:81-90.
7. re Ed. Paris: Editions du Vidal; 1999.
8. O'brien KL, Dowell SF, Schwartz B, Marcy SM, Phillips WR, Gerber MA. Cough illness/bronchitis - Principles of judicious use of antimicrobial agents. Pediatrics 1998;101:178-81.
9. Clarke M, Oxman AD, editors. Cochrane Reviewers' Handbook 4.1 [Updated June 2000]. Review Manager (RevMan) [Computer Program]. Version 4.1. Oxford, England: The Cochrane Collaboration; 2000.
10. Chalumeau M, Duijvestijn YCM, Smucny J, Pons G, Bréart G. Acetylcysteine and carbocysteine for acute respiratory tract infections in paediatric patients without chronic bronchopulmonary disease (Protocol for a Cochrane Review). In: The Cochrane Library, Issue 3, 2001. Oxford: Update Software.
11. Jean R, Gardair F. Utilisation du Fluimucil Antibiotic 750 en Aérosols Chez le Nourrisson et l'Enfant. Paris: Laboratoires Zambon; 1982.
12. Poder G, Puskas J, Kelemen J, Gegesi Kiss A, Cserhati E. Die Wirkung der Langzeitbehandlung mit N-Acetylcystein bei Chronisch-Obstruktiver Bronchitis im Sauglings- und Kleinkindalter. Paris: Laboratoires Zambon; 1982.
13. Bellomo G, Frigerio G, Tirantello G. Ricerche controlatte sull'impiego dell'acetilcisteina per via intramuscolare nelle infezioni respiratorie acute in pediatria. Clin Ter 1967;43:437-58.
14. Bellomo G, Tirantello G, Giudice S. Sull'uso di una combinazione dell'acetilcisteina con tiamfenicolo glicinato nel trattamento sistemico delle infezioni broncopolmonari in eta' pediatrica. Clin Pediatr (Bologna) 1967;49:402-24.
15. Bellomo G, Giudice S. Studio controllato sull'efficacia della combinazione "tiamfenicolo-acetilcisteina" per via orale nel trattamento delle infezioni broncopolmonari dell'infanzia. Clin Pediatr (Bologna) 1972;54:30-51.
16. Bellomo G, Giudice S, Ganci C. Studio comparativo dell'efficacia dell'acetilcisteina per via orale ed intramuscolare nelle affezioni respiratorie acute in pediatria. Minerva Pediatr 1973;25:844-9.
17. Biscatti G, Bruschelli M, Damonte G, Capozzi F. Controlled studies of the clinical effects of acetylcysteine in oral administration in respiratory infections in pediatrics. Minerva Pediatr 1972;24:1075-84.
18. Loscialpo Ramundo D. Sull'impiego della associazone acetilcisteina-tiamfenicolo glicinato in alcune forme di patologia polmonare pediatrica. Clin Pediatr (Bologna) 1968;50:43-56.
19. Mayaud C, Lentschner C, Bouchoucha S, Marsac J. Thiamphenicol glycinate acetylcysteinate in the treatment of acute respiratory infections with mucostasis. Eur J Respir Dis 1980;61(Suppl 111):70-3.
20. Nikolic P, Korac D. The influence of acetylcysteine on respiratory functions in children with recurrent bronchitis. Eur J Respir Dis 1980;61(Suppl 111):141.
21. Ribeiro TM, Cunha LG, Santos M, Frenkiel S. Treatment of bronchial diseases in pediatrics. Results of the use of oral acetylcysteine in 80 cases. Eur J Respir Dis 1980;61(Suppl 111):136-8.
22. Rudnik J, Gawel J, Haluszka J, Kurzawa R, Mielnicka B, Majewska-Zalewska H, et al. Oral acetylcysteine treatment in children with chronic lung diseases. Eur J Respir Dis 1980;61(Suppl 111):140.
23. Szekely E, Farkas E. Treament of chronic bronchitis with oral acetylcysteine in children. Eur J Resp Dis 1980;61(Suppl 111):142.
24. Ramenghi M, Sabayini G, Mengoni M. Combined antibiotic plus mucolytic treatment for recurrent bronchial diseases in infancy. Curr Ther Res 1984;36:664-7.
25. Trastotenojo MS, Harsoyo N, Sachro AD, Soemantri AG, Said HW. Use of acetyl cysteine in respiratory tract disease in children. Paediatr Indones 1984;24:1-10.
26. Gusberti C, Bellazzi A, Lonati C, Modesti R. Valutazione clinica di uno nuovo derivato sintetico dell'acido acetilsalicilico nella terapia di flogosi respiratorie di pazienti pediatrici. Arch Med Interna 1985;37:123-9.
27. Santangelo G, Lombardo S, Giannotti G. A combination of cefuroxime and N-acetyl-cysteine for the treatment of lower respiratory tract infections in children. Int J Clin Pharmacol Ther Toxicol 1985;23:279-81.
28. Fiocchi A, Vignati B, Sala M, Arancio R, Banderali G, Marangione P, et al. La N-acetilcisteina nel trattamento delle broncopneumopatie acute in padietria. G Ital Mal Torace 1989;43:327-34.
29. Camurri S, Marenco G. Valutazione clinica dell'efficacia e della tzollerabilità della nuova formulazione farmaceutica bromessina granulare nei confronti dell'N-acetilcisteina granulare in piccoli pazienti affetti da bronchite acuta. Gazz Med Ital - Arch Sci Med 1990;149:45-8.
30. Samsygina G, Kazyukova T, Vykhristyuk O, Motina A, Tsaregorodtseva L, Dudina T. (Acetylcysteine 100 in treatment of children with acute and chronic respiratory diseases: Experience of use) (Russian). Pediatriya (Moscow) 1995;1:76.
31. Egreteau L, Gaillard D, Jouet JB, Plotkowski L, Zahm JM, Pierrot D, et al. Effect of carbocysteine on mucous and respiratory mucosa in children with recurrent bronchitis. Eur Resp J 1992;5:301s.
32. Banovcin P, Jakusova L, Rosslerova V, Miklerova M, Pullmann R. Carbocysteine in the treatment of recurrent bronchitis in infants. Cesk Pediatr 1992;47:543-6.
33. Malka M, Lablache-Combier B. Intérët d'un mucolytique, la carbocystéine, dans la bronchite aiguë de l'enfant. Med Infant 1990;97:6.
34. Careddu P, Bemocchi D, Scotti L, Manini G, Mezzopane A. Attività terapeutica e tollerabilità di un nuovo farmaco mucoregolatore denominato nesosteina nel trattamento di affezioni acute dell'apparato respiratorio. Studio pediatrico controllato vs carbocisteina. G Ital Mal Torace 1989;43:47-52.
35. Anonyme. Étude de la Tolérance Clinique du Sirop Carbocystéine chez l'enfant. Dossier d'Autorisation de Mise sur le Marché. Aubervilliers: Laboratoires Alpharma; 1987.
36. Michael P, Haase W. Behandlung akuter und chronischer Bronchitis. Therapeutische Erfahrungen mit Pulmoclase. Therapiewoche 1986;36:4440-5.
37. Henocq A, Moreau C, Mallet E, Sauger F, De Menibus CH. Modifications du taux des IgA du mucus nasal au décours des affections des voies aériennes supérieures du nourrisson traitées par la carbocystéine. Ann Otolaryngol Chir Cervicofac 1985;102:373-5.
38. Bemi M, Collina A, Zavattini G. Ambroxol nella patologia broncopolmonare del bambino. Clin Ter 1983;106:351-5.
39. Nigam BK. S-carboxymethylcysteine (S-CMC) in bronchography technique, Indian J Chest Dis Allied Sci 1981;23:81-4.
40. Castello D, Costa G, De Candussio G. Modificazioni dell'escreato nella bronchite catarrale in età pediatrica dopo trattamento con S-carbossimetilcisteina (indagine viscosimetrica). Minerva Pediatr 1979;31:371-80.
41. Ginocchi G. Effeti clinici di un mucolitico (Pol 65) in una casistica pediatrica. Settim Med 1978;66:391-408.
42. Nakayama Y, Maeda K, Fuanabashi S, Kubagawa T, Simanugi K, Tateno K, et al. Effets Cliniques de la S-Carboxymethylcysteine Sous Forme de Sirop en Pédiatrie. Paris: Laboratoires Joullie; 1977.
43. Zanini A, Dodesni G. Il lisomucil in campo pediatrico. Clin Eur 1974;13:1-12.
44. Gaudier B, Lelong M. L'utilisation de la S Carboxy Methyl Cysteine (LJ 206) Dans l'Asthme de l'Enfant. Paris: Laboratoires Joullié; 1968.
45. Anonyme. Acetylcysteine. In: McVoy GK, editor. American Hospital Formulary System Drug Information. Bethesda: American Society of Health-System Pharmacists Incorporation; 2000. p. 2472-4.
46. Anonyme. Acetylcysteine. In: Anonyme, editor. Drug Facts and Comparisons. Saint Louis: Facts and Comparisons; 2000. p. 677-9.
47. European Agency for the Evaluation of Medicinal Products. International Conference on Harmonization. http://www.emea.eu.int/.
48. Remontet L, Mamelle N, Locard E, Lehingue Y. Courbes de croissance de la naissance à 6 ans: Croissance en poids, taille et périmètre crânien selon le sexe. Arch Pédiatr 1999;6:520-9.
49. Hughes J, Gill A, Leach HJ, Nunn AJ, Billingham I, Ratcliffe J, et al. A prospective study of the adverse effects of midazolam on withdrawal in critically ill children. Acta Paediatr 1994;83:1194-9.
50. Horwitz RI, Feinstein AR. The problem of "protopathic bias" in case-control studies. Am J Med 1980;68:255-8.
51. th Edition. Philadelphia: WB Saunders Company; 1998.
52. Anonyme. Agence Française de Sécurité Sanitaire des Produits de Santé. Avis de la Commission de la Transparence, Fluimucil 100 mg. Saint Denis. 2001.
53. e Conférence de Consensus en Thérapeutique Anti-Infectieuse. « Les Infections ORL » Lyon, 19 juin 1996. Texte long du Consensus. Med Mal Infect 1997;27:341-54.
54. Anonyme. Antibiothérapie par voie générale en pratique courante: Infections ORL et respiratoires basses. Rhinopharyngite aiguë. Med Mal Infect 1999;29:221-5.
55. Chalumeau M, Salanave B, Assathiany R, Kemeny J, Bréart G, et le groupe AREPEGE. Connaissance et application par des pédiatres de ville de la conférence de consensus sur les rhinopharyngites aiguës de l'enfant. Arch Pédiatr 2000;7:481-8.