Differential effects of organic calcium-channel blockers on diastolic SR calcium-handling in the frog heart

British Journal of Pharmacology

Volumn 137, Issue 6, 2002, Pages 756-760

  Subramani, Sathya ^a   Vijayanand, Caroline ^a   Tharion, Elizabeth ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Diltiazem; Frog ventricle; Nifedipine; Rest induced decay; Rest induced potentiation; Sarcoplasmic reticular calcium; Verapamil

Indexed keywords

CADMIUM; CALCIUM CHANNEL BLOCKING AGENT; DILTIAZEM; NIFEDIPINE; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DIASTOLE; DRUG EFFECT; DRUG MECHANISM; HEART BEAT; HEART MUSCLE; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; REST; SARCOPLASMIC RETICULUM;

ANIMALS; CADMIUM CHLORIDE; CALCIUM; CALCIUM CHANNEL BLOCKERS; DIASTOLE; DILTIAZEM; HEART VENTRICLES; MYOCARDIAL CONTRACTION; NIFEDIPINE; RANIDAE; SARCOPLASMIC RETICULUM; TIME FACTORS; VERAPAMIL;

EID: 0036855393     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704921     Document Type: Article

References (13)

1. Armstrong, C.M., Bezanilla, F.M. & Horowicz, P. (1972). Twitches in the presence of ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetra acetic acid. Biochim. Biophys. Acta, 267, 605-608.
2. Bean, B.P. (1985). Two kinds of calcium channels in canine atrial cells. J. Gen. Physiol., 86, 1-30.
3. Bigger, Jr. J.T. (1996). Drugs with class IV antiarrhythmic action. In Cecil's Textbook of Medicine. 20th Edn. Vol 1. ed. Bennet, JC. and Plum, F. pp. 250. Philadelphia: WB Saunders.
4. 2+ regulation in mechanically skinned rat skeletal muscle. J. Physiol., 531.3, 729-742.
5. Gonzalez-Serratos, H., Valle-Aguilera, J.R., Lathrop, D.A. & Garcia, M.C. (1982). Slow-inward calcium currents have no obvious role in frog twitch muscle excitation-contraction coupling. Nature, 298, 292-294.
6. Kitazawa, T. (1984). Effect of extracellular calcium on contractile activation in guinea-pig ventricular muscle. J. Physiol., 355, 635-659.
7. Lee, K.S. & Tsien, R.W. (1982). Reversal of current through calcium channels in dialysed single heart cells. Nature, 297, 498-501.
8. Lipp, P. & Pott, L. (1988). Transient inward current in guinea-pig atrial myocytes reflects a change of sodium-calcium exchange current. J. Physiol., 397, 601-630.
9. 2+ release sparks atrial pacemaker activity. NIPS, 16, 101-106.
10. Nilius, B., Hess, P., Lansman, J.B. & Tsien, R.W. (1985). A novel type of cardiac calcium channel in ventricular cells. Nature, 316, 443-446.
11. Oates, J.A. (1996). Antihypertensive agents and the drug therapy of hypertension. In Goodman and Gilman's Pharmacological Basis of Therapeutics. 9th Edn. ed. Hardman, J.G. and Limbird, L.E. pp. 800. New York: McGraw Hill.
12. Reiter, M. (1988). Calcium mobilization and cardiac inotropic mechanisms. Pharmacol. Rev., 40 (3), 189-217.
13. Roden, D.M. (1996). Antiarrhythmic drugs. In Goodman and Gilman's Pharmacological Basis of Therapeutics. 9th Edn. Hardman, J.G. and Limbird, L.E. pp. 854. New York: McGraw Hill.