Neurogenic bladder dysfunction in patients with myelomeningocele

Current Opinion in Urology

Volumn 12, Issue 6, 2002, Pages 469-472

  Madersbacher, Helmut ^a  

^a Landeskrankenhaus University Hospital   (Austria)

Author keywords

Acute abdomen; Detethering benefits; Detrusor sphincter dysfunction; Myelodyplasia; Pharmacotherapy; Sphincter augmentation; Urodynamics

Indexed keywords

CAPSAICIN; CHOLINERGIC RECEPTOR BLOCKING AGENT; COLLAGEN; GLYCOSAMINOGLYCAN; LIDOCAINE; OXYBUTYNIN; RESINIFERATOXIN;

ACUTE ABDOMEN; ADOLESCENT; BLADDER SPHINCTER; CHILD; CLINICAL FEATURE; COGNITIVE DEFECT; CONSTIPATION; DETRUSOR DYSSYNERGIA; DETRUSOR MUSCLE; DROWSINESS; DRUG FORMULATION; DRUG INDUCED DISEASE; FEMALE; FOLLOW UP; HUMAN; INTERMITTENT CATHETERIZATION; MALE; MENINGOMYELOCELE; MYELODYSPLASIA; NEUROGENIC BLADDER; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REVIEW; SCHOOL CHILD; SYMPTOM; TETHERED CORD SYNDROME; TREATMENT PLANNING; URINARY EXCRETION; URODYNAMICS; XEROSTOMIA;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; HUMANS; INFANT; MENINGOMYELOCELE; URINARY BLADDER, NEUROGENIC; URODYNAMICS;

EID: 0036855191     PISSN: 09630643     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042307-200211000-00004     Document Type: Review

References (13)

1. Van Gool JD, Dik P, de Jong TP. Bladder-sphincter dysfunction in myelomeningocele. Eur J Pediatr 2001; 160:414-420. A straight forward strategy, how to treat children with myelodysplasie, bsaed on urodynamic findings is presented.
2. Glott T, Stanghelle JK, Rand-Hendriksen S, et al. Follow up of urinary tract problems in adults with myelomeningocele. Tidsskr Nor Laegeforen 2001; 121:1247-1251. Only the ultimate outcome, once these patients are adolescents or adults, will retrospectively allow a judgement how effective our efforts are: one of the very few papers dealing with this topic.
3. Salvaggio E, Antuzzi D, Ferrara P, et al. Clycosaminoglycans: Urinary excretion in children with myelomeningocele. Urol Int 2001; 66:156-159. GAG excretion, increased in myelodysplasia patients older than 5 years, may indicate beginning bladder damage.
4. Tarcan T, Bauer S, Olmedo E, et al. Long-term followup of newborns with myelodysplasia and normal urodynamic findings: Is followup necessary? J Urol 2001; 165:564-567. Also children with normal urodynamics after repair of the spinal defect deserve careful follow-up: in 30% deterioration occurs during the first 5 years of life, mainly due to secondary tethering; only early diagnosis and correction provides good results with detethering.
5. Ferrara P, d'Alea CM, Tarquini E, et al. Side-effects of oral or intravesical oxybutynin chloride in children with spina bifida. BJU Int 2001; 87:674-678. Also intravesical oxybutynin may cause cognitive impairment and other side effects which may differ from those with oral application.
6. Lapointe SP, Wang B, Kennedy WA, Shortliffe LM. The effects of intravesical lidocaine on bladder dynamics of children with myelomeningocele. J Urol 2001; 165(6 Pt 2):2380-2382.
7. Youdim K, Kogan BA. Preliminary study of the safety and efficacy of extended-release oxybutynin in children. Urology 2002; 59:428-432.
8. Seki N, Ikawa S, Takano N, Naito S. Intravesical instillation of resiniferatoxin for neurogenic bladder dysfunction in a patient with myelodysplasia. J Urol 2001; 166:2366-2369. Based on one case-report the value of Resiniferatoxin intravesically as an alternative to treat detrusor-overactivity is demonstrated.
9. Kassouf W, Capolicchio G, Berardinucci G, Corcos J. Collagen injection for treatment of urinary incontinence in children. J Urol 2001; 165:1666-1668. Collagen injections are rarely effective in treating children with neurogenic sphincter underactivity and are therefore no alternative to operative treatment.
10. Worley G, Wiener JS, GeorgeTM, et al. Acute abdominal symptoms and signs in children and young adults with spina bifida: Ten years experience. J Pediatr Surg 2001; 36:1381-1386. Myelomeningocele children suffering from acute abdominal symptoms should possibly be transferred to a center which is familiar with reasons and treatment modalities of this complex condition.
11. Knoll M, Madersbacher H. The chances of a spina bifida patient becoming continent/socially dry by conservative management. Paraplegia 1993; 31:22-27.
12. Lackner J, Kiss G, Madersbacher H. Can early urological management improve the outcome (upper urinary tract, continence) in patients with myelomeningocele? Long term results. J Neuro Urol 2000.
13. Madersbacher H, Knoll M. Intravesical application of oxybutynine: Mode of action in controlling detrusor-hyperreflexia, preliminary results. Eur Urol 1995; 28:340-344.