PCR for the diagnosis of toxoplasmosis after hematopoietic stem cell transplantation

Expert Review of Molecular Diagnostics

Volumn 2, Issue 6, 2002, Pages 616-624

  Lewis Jr , James S ^a   Khoury, Hanna ^b   Storch, Gregory A ^c   DiPersio, John ^b  

^a WASHINGTON UNIVERSITY   (United States)

^b Div Bone Marrow Transplant H   (United States)

^c Division of Infectious Diseases   (United States)

Author keywords

Diagnosis; Hematopoietic stem cell transplantation; PCR; Toxoplasmosis

Indexed keywords

BIOPSY; DIAGNOSTIC ACCURACY; EARLY DIAGNOSIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNE DEFICIENCY; POLYMERASE CHAIN REACTION; REVIEW; SEROLOGY; TOXOPLASMA GONDII; TOXOPLASMOSIS; ANIMAL; BLOOD; COMPUTER SYSTEM; ECONOMICS; EPIDEMIOLOGY; FORECASTING; GENETICS; IMMUNOLOGY; MASS SCREENING; METHODOLOGY; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PREMEDICATION; SENSITIVITY AND SPECIFICITY; TOXOPLASMA;

ANTIPROTOZOAL AGENT; COTRIMOXAZOLE; PROTOZOAL DNA; PROTOZOON ANTIBODY;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIPROTOZOAL AGENTS; COMPUTER SYSTEMS; DNA, PROTOZOAN; FORECASTING; HUMANS; IMMUNOCOMPROMISED HOST; MASS SCREENING; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; POLYMERASE CHAIN REACTION; PREMEDICATION; SENSITIVITY AND SPECIFICITY; SEROEPIDEMIOLOGIC STUDIES; TOXOPLASMA; TOXOPLASMOSIS; TOXOPLASMOSIS, CEREBRAL; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 0036855127     PISSN: 14737159     EISSN: None     Source Type: Journal    
DOI: 10.1586/14737159.2.6.616     Document Type: Review

References (38)

1. Montoya JG. Laboratory diagnosis of Taxoplasma gondii infection and toxoplasmosis. J. Infect. Dis. 185(Suppl. 1), S73-82 (2002). Excellent review of laboratory diagnosis of toxoplasmosis, particularly nonmolecular methods.
2. th Edition). Mandell GL, Bennett JE and Dolin R (Eds), Churchill Livingston Inc, PA, USA, 2558-2888 (2000).
3. Porter SB, Sande MA. Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. NEJM 327(23), 1643-1648 (1992).
4. Leport C, Chene G, Morlat P et al. Pyrimethamine for primary prophylaxis of toxoplasmic encephalitis in patients with human immunodeficiency infection. A double-blind, randomized trial. J. Infect. Dis. 173, 91-97 (1996).
5. Ammassari A, Scoppettuolo G, Murri R et al. Changing disease patterns in focal brain lesion-causing disorders in AIDS. J. Acquir. Immun. Defic. Synd. Hum. Retravirol. 18, 365-371 (1998).
6. Mele A, Paterson PJ, Prentice HG, Leoni P, Kibbler CC. Toxoplasmosis in bone marrow transplantation: A report of two cases and systematic review of the literature. Bone Marrow Transplant. 29, 691-698 (2002). Largest review of toxoplasmosis after hematopoietic stem cell transplant (HSCT) (110 cases).
7. Slavin MA, Meyers JD, Remington JS, Hackman RC. Toxoplasma gondii infection in marrow transplant recipients: A 20 year experience. Bone Marrow Transplant. 13, 549-557 (1994).
8. Derouin F, Devergie A, Auber P, Gluckman E, Beauvais B, Garin YJF. Toxoplasmosis in bone marrow transplant recipients: report of seven cases and review. Clin. Inf. Dis. 15, 267-270 (1992).
9. Martino R, Maertens J Bretagne S et al. Toxoplasmosis after hematopoietic stem cell transplantation. Clin. Inf. Dis. 31, 1188-1194 (2000).
10. Skeist DJ. Focal neurological disease with the acquired immunodeficiency syndrome. Clin. Inf. Dis. 34, 103-115 (2002).
11. Bretagne S, Costa JM, Foulet F, Jabot-Lestang L, Baud-Camus F, Cordonnier C. Prospective study of toxoplasma reactivation by polymerase chain reaction in allogeneic stem-cell transplant recipients. Transplant Inf. Dis. 2(3), 127-132 (2000). Only study evaluating prospective blood PCR for toxoplasmosis detection - Discussion of issues.
12. Ortonne N, Ribaud P, Meignin V et al. Toxoplasmic pneumonitis leading to fatal acute respiratory distress syndrome after engraftment in three bone marrow transplant recipients. Transplantation 72(11), 1838-1840 (2001).
13. Klepser ME, Klepser TB. Drug treatment of HIV-related opportunistic infections. Drugs 53(1), 40-73 (1997).
14. Ammassari A, Murri R, Cingolani A, De Luca A, Antinori A. AIDS-associated cerebral toxoplasmosis: An update on diagnosis and treatment. Curr Top. Micro. Imm. 219, 209-222 (1996).
15. Luft BJ, Hafner R, Korzun AH et al. Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. NEJM 329(14), 995-1000 (1993).
16. Mathews C, Barba D, Fullerton SC. Early biopsy versus empiric treatment with delayed biopsy of non-responders in suspected HIV-associated cerebral toxoplasmosis: A decision analysis. AIDS 9(11), 1243-1250 (1995).
17. Fung H, Kirschenbaum HL. Treatment regimens for patients with toxoplasmic encephalitis. Clin. Ther. 18(6), 1037-1056 (1996).
18. Sing A, Leitritz L, Roggenkamp A et al. Pulmonary toxoplasmosis in bone marrow transplant recipients: report of two cases and review. Clin. Inf. Dis. 29, 429-433 (1999).
19. Skolasky RL, Dal Pan GJ, Olivi A, Lenz FA, Abrams RA, McArthur JC. HIV associated primary central nervous system lymphoma - Morbidity and utility of brain biopsy. J. Neurol. Sci. 163(1), 32-38 (1999).
20. Rodriguez JC, Martinez MM, Martinez AR, Royo G. Evaluation of different techniques in the diagnosis of toxoplasma encephalitis. J. Med. Micro. 46, 597-601 (1997).
21. Roberts T, Storch G. Multiplex PCR for diagnosis of AIDS related central nervous system lymphoma and toxoplasmosis. J. Clin. Micro. 35(1), 268-269 (1997).
22. Gratzl R, Hayde M, Kolhauser C, Hermon M, Burda G, Strobl W. Follow-up of infants with congenital toxoplasmosis detected by polymerase chain reaction analysis of amniotic fluid. Eur. J. Clin. Micro. Inf. Dis. 17(12), 853-858 (1998).
23. Hohlfield P, Daffos F, Costa JM et al. Prenatal diagnosis of congenital toxoplasmosis with a PCR test on amniotic fluid. NEJM 331(11), 695-699 (1994).
24. Danise A, Cinque P, Vergani S, Candino M, Racca S, De Bona A. Use of polymerase chain reaction assays of aqueous humor in the differential diagnosis of retinitis in patients infected with human immunodeficiency virus. Clin. Inf. Dis. 24(6), 1100-1106 (1997).
25. Bou G, Figueroa MS, Marti-Belda P, Navas E, Guerrero A. Value of PCR for detection of Toxoplasma gondii in aqueous humor and blood samples from immunocompetent patients with ocular toxoplasmosis. J. Clin. Micro. 37(11), 3465-3468 (1999).
26. Bretagne S, Costa JM, Vidaud M, Tran J, Nhieu V, Fleury-Feith J. Detection of Toxoplasma gondii by competitive DNA amplification of bronchoalveolar lavage samples. J. Infect. Dis. 168(6), 1585-1588 (1993).
27. Khoury H, Adkins D, Brown R et al. Successful treatment of cerebral toxoplasmosis in a marrow transplant recipient: Contribution of a PCR test in diagnosis and early detection. Bone Marrow Transplant. 23, 409-411 (1999).
28. Lamoril J, Molina JM, de Gouvello A et al. Detection by PCR of Toxoplasma gondii in blood in the diagnosis of cerebral toxoplasmosis in patients with AIDS. J. Clin. Path. 49(1), 89-92 (1996).
29. Lin MH, Kuo TT. Specificity of the histopathological triad for the diagnosis of toxoplasmic lymphadenitis: Polymerase chain reaction study. Path. Intern. 51(8), 619-623 (2001).
30. Holliman RE, Johnson JD, Savva D. Diagnosis of cerebral toxoplasmosis in association with AIDS using the polymerase chain reaction. Scan. J. Inf. Dis. 22(2), 243-244 (1990).
31. Costa JM, Pautas C, Ernault P, Foulet F, Cordonnier C, Bretagne S. Real-time PCR for diagnosis and follow-up of toxoplasma reactivation after allogeneic stem cell transplantation using fluorescence resonance energy transfer hybridization probes. J. Clin. Microbiol. 38(8), 2929-2932 (2000). Quantitative PCR to follow patients after initial screening PCR.
32. Koenig M, Reynolds KS, Aldous W, Hickman M. Comparison of light-cyder PCR, enzyme immunoassay and tissue culture for detection of herpes simplex virus. Diagn. Micro. Infect. Dis. 40(3), 107-110 (2001).
33. Franzen C, Altfed M, Hegener P et al. Limited value of PCR for detection of Toxoplasma gondii in blood from human immunodeficiency virus-infected patients. J. Clin. Micro. 35(10), 2639-2641 (1997).
34. Foudrinier F, Aubert D, Puygauthier-Toubas D et al. Detection of Toxoplasma gondii in immunodeficient subjects by gene amplification: Influence of therapeutics. Scand. J. Inf. Dis. 28, 383-386 (1996).
35. Kelley VA, Caliendo AM. Successful testing protocols in virology. Clin. Chem. 47(8), 1559-1562 (2001).
36. Parmley S, Slifer T, Araujo F. Protective effects of immunization with a recombinant cyst antigen in mouse models of infection with Toxoplasma gondii tissue cysts. J. Inf. Dis. 185(S1), S90-95 (2002).
37. Cingolani A, DeLuca A, Ammassari A et al. Detection of T. gondii DNA by PCR in AIDS-related toxoplasmic encephalitis. J. Euk. Micro. 43(5), 118S-119S (1996).
38. Parmley SF, Goebel FD, Remington JS. Detection of Toxoplasma gondii in cerebrospinal fluid from AIDS patients by polymerase chain reaction. J. Clin. Micro. 30(11), 3000-3002 (1992).