Antiemetic use in pediatric gastroenteritis: A national survey of emergency physicians, pediatricians, and pediatric emergency physicians

Clinical Pediatrics

Volumn 41, Issue 9, 2002, Pages 641-652

  Kwon, Kenneth T ^a   Rudkin, Scott E ^a   Langdorf, Mark I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIEMETIC AGENT; ANTIHISTAMINIC AGENT; CHLORPROMAZINE; DIPHENHYDRAMINE; DROPERIDOL; METOCLOPRAMIDE; ONDANSETRON; PETHIDINE; PROCHLORPERAZINE; PROCHLORPERAZINE MALEATE; PROMETHAZINE; TRIMETHOBENZAMIDE;

AGITATION; AKATHISIA; APNEA; ARTICLE; CENTRAL NERVOUS SYSTEM DEPRESSION; CENTRAL NERVOUS SYSTEM DISEASE; CHRONIC DRUG ADMINISTRATION; CONSCIOUSNESS DISORDER; CONSTIPATION; DEHYDRATION; DEPRESSION; DIARRHEA; DROWSINESS; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG INDUCED DISEASE; DRUG SAFETY; DRUG USE; DYSKINESIA; DYSTONIA; EMERGENCY MEDICINE; EXTRAPYRAMIDAL SYMPTOM; FACIAL NERVE PARALYSIS; FATIGUE; GASTROENTERITIS; GYNECOMASTIA; HALLUCINATION; HEADACHE; HUMAN; HYPERREFLEXIA; HYPOTENSION; LONG QT SYNDROME; MEDICAL SPECIALIST; METHEMOGLOBINEMIA; MOTOR DYSFUNCTION; MUSCLE SPASM; NEUROLEPTIC MALIGNANT SYNDROME; NEUROMUSCULAR DISEASE; NORMAL HUMAN; OCULOGYRIC CRISIS; PEDIATRICS; PRESCRIPTION; RESTLESSNESS; SACCHAROMYCES; SEDATION; SEIZURE; SUDDEN INFANT DEATH SYNDROME; TACHYCARDIA; TARDIVE DYSKINESIA; TORSADE DES POINTES; TREMOR; TRISMUS; VISUAL HALLUCINATION;

ANTIEMETICS; CHILD; CROSS-SECTIONAL STUDIES; DRUG UTILIZATION REVIEW; EMERGENCY MEDICINE; GASTROENTERITIS; HUMANS; PEDIATRICS; PHYSICIANS;

EID: 0036850857     PISSN: 00099228     EISSN: None     Source Type: Journal    
DOI: 10.1177/000992280204100902     Document Type: Article

References (88)

1. Perez EA, Hesketh P, Sandbach, et al. Comparison of single-dose oral granisetron versus intravenous ondansetron in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy: A multicenter, double-blind, randomized parallel study. J Clin. Oncol. 1998;16:754-760
2. Splinter WM, Rhine EJ. Prophylactic antiemetics in children undergoing tonsillectomy: High-dose vs. low-dose ondansetron. Paediatr Anaesth. 1997;7:125-129
3. Morton NS, Camu F, Dorman T, et al. Ondansetron reduces nausea and vomiting after paediatric adenotonsillectomy. Paediatr Anaesth. 1997;7:37-45
4. Davis PJ, McGowan FX, Landsman I, et al. Effect of antiemetic therapy on recovery and hospital discharge time: A double-blind assessment of ondansetron, droperidol, and placebo in pediatric patients undergoing ambulatory surgery. Anesthesiology. 1995;83:956-960
5. Schwella N, Konig V, Schwerdtfeger M, et al. Ondansetron for efficient emesis control during total body irradiation. Bone Marrow Transplant. 1994;13:169-171
6. Billett AL, Salla SE. Antiemetics in children receiving cancer chemotherapy. Support Care Cancer. 1994;2:279-285
7. Relling MV, Mulhern RK, Fairclough D, et al. Chlorpromazine with and without lorazepam as antiemetic therapy in children receiving uniform chemotherapy. J Pediatr. 1993;123:811-816
8. Olver IN, Wof M, Laidlaw C et al. A randomized double-blind study of high-dose intravenous prochlorperazine versus high-dose metoclopramide as antiemetics for cancer chemotherapy. Eur J Cancer. 1992;28A:1798-1802
9. Marshall G, Kerr S, Vowels M, et al. Antiemetic therapy for chemotherapy-induced vomiting: Metoclopramide, benztropine, dexamethasone, and lorazepam regimen compared with chlorpromazine alone. J Pediatr. 1989;115:156-160
10. Graham-Pole J, Weare J, Engel S, et al. Antiemetics in children receiving cancer chemotherapy: A double-blind prospective randomized study comparing metoclopramide with chlorpromazine. J Clin Oncol. 1986;4:1110-1113
11. Glass R, Lew J, Gangarosa R, et al. Estimates of morbidity and mortality rates for diarrheal diseases in American children. J Pediatr. 1991;118:S27-S33
12. Ho MS, Glass RI, Pinsky PF, et al. Diarrheal deaths in American children: Are they preventable? JAMA. 1988;260:3281-3285
13. Provisional Committee on Quality Improvement, Subcommittee on Acute Gastroentereitis. Practice parameter: The management of acute gastroenteritis in young children. Pediatrics. 1996;97:424-435
14. Kumar GA, Little TM. Has treatment for childhood gastroenteritis changed? BMJ. 1985;290:1321-1322
15. Morrison PS, Little TM. How is gastroenteritis treated? BMJ. 1981;283:1300
16. Chuang M, Kamath KR. Preadmission management of acute gastroenteritis in children. Med J Austr. 1991;154:565
17. Jaudes PK, Christoffel KK. Differences among physicians in the treatment of children with vomiting. Fam Pract Res J. 1986;6:47-53
18. Choonara IA, Shoo EE, Owens GG. Prescribing habits for children with acute gastroenteritis: A comparison over 5 years. Br J Clin Pharmacol. 1987;23:362-364
19. The Official ABMS Directory of Board Certified Medical Specialists 1999 (31st Edition). New Providence, NJ: Reed Elsevier; 1999
20. Borison HL, Wang SC. Physiology and pharmacology of vomiting. Pharmacol Rev. 1953;5:193-230
21. Barsan WG, Lowell MJ, Wolf LR. Disorders of the upper gastrointestinal tract. In Rosen P, Barkin R, eds. Emergency Medicine: Concepts and Clinical Practice, 4th Ed. St. Louis, MO: Mosby-Year Book: 1998:1960-1961
22. Williams C. Causes and management of nausea and vomiting. Nursing Times. 1994;90:38-41
23. Hockenberry-Eaton M, Benner A. Patterns of nausea and vomiting in children: Nursing assessment and intervention. Oncol Nurs Forum. 1990;17:575-584
24. Ordog GJ, Vann PW, Owashi ND, et al. Intravenous prochlorperazine for the rapid control of vomiting in the emergency department. Ann Emerg Med. 1984;13:253-258
25. Lankamp DJ, Willemese J, Pikaar SA, et al. Prochlorperazine in childhood: Side-effects. Clin Neurol Neurosurg. 1977;80:264-271
26. Prochlorperazine. Physicians’ Desk Reference, 54th Ed. Montvale, NJ: Medical Economics Co, 2000:2986-2988
27. Ernst AA, Weiss SJ, Park S, et al. Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: A randomized, double-blind clinical trial. Ann Emerg Med. 2000;36:89-94
28. Bardfeld PA. A controlled doubleblind study of trimethobenzamide, prochlorperazine, and placebo. JAMA. 1966;196:796-798
29. Prochlorperazine. Drug Information Handbook, 4th Ed. Hudson, OH: Lexi-Comp Inc; 1996:998
30. Bush RT. Acute reactions to prochlorperazine ("stemetil") in children: A report of four cases. N Z Med J. 1966;65:229-231
31. Melnick A, Berger R. Phenothiazine reactions in children: Review of side effects with particular reference to prochlorperazine. Clin Pediatr. 1967;6:309-311
32. Cottom DG, Newman CGH. Dystonic reactions to phenothiazine derivatives. Arch Dis Child. 1966;41:551-553
33. Berk BZ. Reaction of prochlorperazine? Lancet. 1969;1(7598):776
34. Browning DH, Ferry PC. Tardive dyskinesia in a ten-year-old boy; an undesirable sequel of phenothiazine medication. Clin Pediatr. 1976;15:955-957
35. Ravindran M. Dystonic syndrome after compazine therapy. South Med J. 1978;71:615
36. Bejar JM. Compazine-induced dyskinesia in a 14-month-old boy. Clin Neuropharmacol. 1984;7:171-172
37. Baker FM, Cook P. Compazine complications: A review. J Natl Med Assoc. 1981;73:409-412
38. Bhopale S, Seidel JS. Dystonic reaction to a phenothiazine presenting as Bell’s palsy. Ann Emerg Med. 1997;30:234-236
39. Promethazine. Physicians’ Desk Reference, 54th Ed. Montvale, NJ: Medical Economics Co; 2000:3291-3293
40. Hickson GB, Altemeier WA, Clayton EW. Should promethazine in liquid form be available without prescription? Pediatrics. 1990;86:221-225
41. Buck ML, Blumer JL. Phenothizaineassociated apnea in two siblings. Ann Pharmacother 1991;25:244-247
42. Pollard AJ, Rylance G. Inappropriate prescribing of promethazine in infants. Arch Dis Child. 1994;70:357
43. Kahn A, Blum D. Possible role of phenothiazines in suddent infant death. Lancet. 1979;1:364
44. Kahn A, Blum D. Phenothiazines and sudden infant death syndrome. Pediatrics. 1982;70:75-78
45. Kahn A, Hasaerts D, Blum D. Phenothiazine-induced sleep apneas in normal infants. Pediatrics. 1985;75:844-847
46. Rosefsky JB. Should promethazine be availabe without prescription? Pediatrics. 1991;88:877-879
47. Darwish H, Grant R, Haslam R. Promethazine-induced acute dystonic reactions. Arch Dis Child. 1980;134:990-991
48. DeGrandi T, Simon JE. Promethazine-induced dystonic reaction. Pediatr Emerg Care. 1987;3:91-92
49. Fisher SE. Encephalitic reaction to promethazine. J Pediatr. 1972;80:896-897
50. Dollberg S, Hurvitz H, Kerem E, et al. Hallucinations and hyperthermia after promethazine ingestion. Act Paediatr. 1989;78:131-132
51. Shawn DH, McGuigan MA. Poisoning from dermal absorption of promethazine. CMA J. 1984;130:1460-1461
52. Pan CV, Quintela AG, Anuncibay PG. Topical promethazine intoxication. Ann Pharmacother. 1989;23:89
53. Ondansetron. Physicians Desk Reference, 54th Ed. Montvale, NJ: Medical Economics Co; 2000:1318-1324
54. Cubeddu LX, Trujillo LM, Talmaciu I, et al. Antiemetic activity of ondansetron in acute gastroenteritis. Aliment Pharmacol Ther. 1997;11:185-191
55. Nahata MC, Hui LN, Koepke J. Efficacy and safety of ondansetron in pediatric patients undergoing bone marrow transplantation. Clin Ther. 1996;18:466-476
56. Jurgens H, McQuade B. Ondansetron as prophylaxis for chemotherapy and radiotherapy-induced emesis in children. Oncology. 1992;49:279-285
57. Sullivan MJ, Abbott GD, Robison BA. Ondansetron antiemetic therapy for chemotherapy and radiotherapy induced vomiting in children. N Z Med J. 1992;105:369-370
58. Marty MM, Pouillar P, Scholl S, et al. Comparison of the hydroxytryptamine (serotonin) antagonist ondansetron (GR38032F) with high-dose metoclopramide in the control of cisplatin-induced emesis. N Engl J Med. 1990;322:816-821
59. Stene EN, Russell ES, Young LA, et al. Prospective, randomized, double-blind, placebo-controlled comparison of metoclopramide and ondansetron for prevention of posttonsillectomy or adenotonsillectomy emesis. J Clin Anesth. 1996;8:540-544
60. Polati E, Verlato G, Finco G, et al. Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. Anesth Analg. 1997;85:395-399
61. van den Berg AA. Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy. B J Anaesth. 1996;76:449-451
62. Tobias JD, Gregory DF, Deshpande JK. Ondansetron to prevent emesis following n-acetylcysteine for acetaminophen intoxication. Pediatr Emerg Care. 1992;8:345-346
63. Clark RF, Chen R, Williams SR, et al. The use of ondansetron in the treatment of nausea and vomiting associated with acetaminophen poisoning. Clin Toxicol. 1996;34:163-167
64. Reed MD, Marx CM. Ondansetron for treating nausea and vomiting in the poisoned patient. Ann Pharmacother. 1994;28:331-333
65. Finn AL. Toxicity and side effects of ondansetron. Semin Oncol. 1992;19:53-60
66. Camp-Sorrell D. Managing an extrapyramidal reaction caused by ondansetron. Oncol Nurs Forum. 1995;22:718-719
67. Metoclopramide. Physicians’ Desk Reference, 54th Ed. Montvale, NJ: Medical Economics Co; 2000:2603-2605
68. Bateman DN. Clinical pharmacokinetics of metoclopramide. Clin Pharmacokinet. 1983;8:523-529
69. Casteels-vanDaele M, Jaeken J, vanderSchueren P, et al. Dystonic reactions in children caused by metoclopramide. Arch Dis Child. 1970;45:130-133
70. Batts KF, Munter DW. Metoclopramide toxicity in an infant. Pediatr Emerg Care. 1998;14:39-41
71. Guala A, Mittino D, Fabbrocini P, Ghini T. Familial metoclopramide-induced dystonic reactions. Mov Disord. 1992;7:385-386
72. Upham JW. Dystonic reaction to metoclopramide. Med J Austr. 1983;1(1):12
73. Gupte S. Dystonic reactions following metoclopramide therapy. Indian J Pediatr. 1982;50:291-292
74. Casteels-van Daele. Metoclopramide poisoning in children. Arch Dis Child. 1981;56:405-407
75. Sills JA, Glass EJ. Metoclopramide in young children. BMJ. 1978;2(6153):1713
76. Wood GD. An adverse reaction to metoclopramide therapy. Br J Oral Surg. 1977;15:278-280
77. Putnam PE, Orenstein SR, Wessel HB, et al. Tardive dyskinesia associated with use of metoclopramide in a child. J Pediatr 1992;121:983-985
78. Wilson CM, Bird SG, Bocash W, et al. Methemoglobinemia following metoclopramide therapy in an infant. J Pediatr Gastroenterol Nutr. 1987;6:640-642
79. Ozsoylu S. Methaemoglobinaemia following metoclopramide. Eur J Pediatr. 1988;148:172
80. Madani S, Tolia V. Gynecomastia with metoclopramide use in pediatric patients. J Clin Gastroenterol. 1997:24:79-81
81. Trimethobenzamide. Physicians’ Desk Reference, 54th Ed. Montvale, NJ: Medical Economics Co; 2000:2596-2597
82. Ginsburg CM, Clahsen J. Evaluation of trimethobenzamide hydrochloride (Tigan) suppositories for treatment of nausea and vomiting in children. J Pediatr. 1980;96:767-769
83. Trimethobenzamide hydrochloride. Drug Information Handbook, 4th Ed. Hudson, OH: Lexi-Comp Inc; 1996:1200
84. Holmes C, Flaherty RJ. Trimethobenzamide hydrochloride (Tigan)-induced extrapyramidal dysfunction in a neonate. J Pediatr. 1976;89:669-670
85. Joshi PT, Hamel L, Joshi ART, et al. Use of droperidol in hospitalized children. J Am Acad Child Adolesc Psychiatr. 1998;37:228-230
86. Blanc VF, Ruest P, Milot, J, et al. Antiemetic prophylaxis with promethazine or droperidol in paediatric outpatient strabismus surgery. Can J Anaesth. 1991;38:54-60
87. Fassoulaki A, Galanaki E. The antiemetic effect of droperidol: Is it dose dependent? Acta Anaesthesiol Belg. 1989;40:179-182
88. Verheecke G, Troch E. Oral droperidol for premedication in children. Acta Anaesthesiol Belg. 1985;4:421-426