Targeted disruption of Slc19a2, the gene encoding the high-affinity thiamin transporter Thtr-1, causes diabetes mellitus, sensorineural deafness and megaloblastosis in mice

Human Molecular Genetics

Volumn 11, Issue 23, 2002, Pages 2951-2960

  Di Giaimo, Rossella ^a,d   Riccio, Massimo ^b   Santi, Spartaco ^b   Galeotti, Cesira ^c   Ambrosetti, Davide C ^a   Melli, Marialuisa ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CNR   (Italy)

^c CHIRON VACCINES   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; INSULIN; THIAMINE; THIAMINE TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BONE MARROW; BONE MARROW CELL; CELL LINE; DIABETES MELLITUS; DIET RESTRICTION; DIETARY INTAKE; DISEASE MODEL; EMBRYO CELL; ERYTHROCYTE; ERYTHROID CELL; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE CONSTRUCT; GENE DISRUPTION; GENE MUTATION; GENE TARGETING; GENETIC CODE; GENETIC RECOMBINATION; HOMEOSTASIS; INSULIN RELEASE; INSULIN RESPONSE; MEGAKARYOCYTE; MEGALOBLASTIC ANEMIA; MOUSE; MUTAGENESIS; NONHUMAN; PATHOGENESIS; PERCEPTION DEAFNESS; PRIORITY JOURNAL; PROTEIN TRANSPORT; STEM CELL; THIAMINE DEFICIENCY; TRANSPOSON; WILD TYPE;

ANEMIA, MEGALOBLASTIC; ANIMALS; BONE MARROW; BRAIN; DIABETES MELLITUS; DNA PRIMERS; ERYTHROCYTES; GENE DELETION; GENE TARGETING; GLUCOSE; HEARING LOSS, SENSORINEURAL; INSULIN; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; PANCREAS; POLYMERASE CHAIN REACTION; THIAMINE;

ANIMALIA; CUCURBITA; TRANSPOSONS;

EID: 0036850440     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

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