Modelling the effect of incorporated halogenated pyrimidine on radiation-induced DNA strand breaks

International Journal of Radiation Biology

Volumn 78, Issue 11, 2002, Pages 953-966

  Watanabe, R ^a   Nikjoo, H ^b  

^a JAPAN ATOMIC ENERGY AGENCY   (Japan)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; DNA; PYRIMIDINE; RADICAL; URACIL;

ARTICLE; DNA DAMAGE; DNA STRAND BREAKAGE; ENERGY TRANSFER; MONTE CARLO METHOD; PHOTON; PRIORITY JOURNAL; X IRRADIATION; X RAY;

BASE SEQUENCE; BROMODEOXYURIDINE; CHROMOSOME BREAKAGE; COMPUTER SIMULATION; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; FREE RADICALS; IDOXURIDINE; LINEAR ENERGY TRANSFER; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; RADIATION TOLERANCE; URACIL; WATER;

EID: 0036849052     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/0955300021000024270     Document Type: Article

References (66)

1. Abdoul-Carime, H., Dugal, P.-C. and Sanche, L., 2000, Damage induced by 1-30 eV electrons on thymine- and bromouracil-substituted oligonucleotides. Radiation Research, 153, 23-28.
2. Adams, G. E. and Willson, R. L., 1972, On the mechanism of BUdR sensitization: A pulse radiolysis study of one electron transfer in nucleic acid derivatives. International Journal of Radiation Biology, 22, 589-597.
3. Andersen, R. F., Petel, K. B. and Wilson, W. R., 1991, Pulse radiolysis studies of electron migration in DNA from DNA base-radical anions to nitroacridine intercalators in aqueous solution. Journal of the Chemical Society, Faraday Transactions, 87, 3739-3746.
4. Beach, C., Fuciarelli, A. F. and Zimbrick, J. D., 1994, Electron migration along 5-bromouracil-substituted DNA irradiated in solution and in cells. Radiation Research, 137, 385-393.
5. Buxton, G. V. Greenstock, C. L., Helman, W. P. and Ross, A. B., 1988, Critical review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals in aqueous solution. Journal of Physical Chemistry Reference Data, 17, 513-586.
6. 125I. International Journal Radiation Biology, 53, 353-365.
7. Charlton, D. E. and Nikjoo, H., 1992, Calculation of the physical parameters responsible for the enhancement of radiation damage due to the incorporation of Br/I atoms into the DNA. In R. W. Howell, V. R. Narra, K. S. R. Sastry and D. V. Rao (eds), Biophysical Aspects of Auger Processes. AAPM Symposium Series No. 8 (American Association of Physicists in Medicine), pp. 51-65.
8. Charlton, D. E., Nikjoo, H., and Humm, J. L., 1989, Calculation of initial yields of single- and double-strand breaks in cell nuclei from electrons, protons and alpha particles. International Journal of Radiation Biology, 56, 1-19.
9. Chatterjee, A. and Magee, J. L., 1986, Theoretical investigation of the production of strand breaks in DNA by water radicals. Radiation Protection Dosimetry, 13, 137-140.
10. Cullis, P. M., McClymont, J. D. and Symons, M. C. R., 1990, Electron conduction and trapping in DNA. An electron spin resonance study. Journal of the Chemical Society, Faraday Transactions, 86, 591-592.
11. Dee, D. and Baur, M. E., 1974, Charge and excitation migration in DNA chains. Journal of Chemical Physics, 60, 541-560.
12. Deeble, D. J. and Von Sonntag, C., 1984, γ-radiolysis of poly(U) in aqueous solution. The role of primary sugar and base radicals in the release of undamaged uracil. International Journal of Radiation Biology, 46, 247-260.
13. Fielden, E. M. Lillicrap, S. C. and Robins, A. B, 1971, The effect of 5-bromouracil on energy transfer in DNA and related model systems: DNA with incorporated 5-BUdR. Radiation Research, 48, 421-431.
14. Fitzsimons, C. J., Nikjoo, H., Bolton, C. E. and Goodhead, D. T., 1998, A novel algorithm for tracing the interaction of a track with molecular targets - Use of Delaunay triangulation. Mathematical Biosciences, 154, 103-115.
15. Foray, N., Arlett, C. F. and Malaise, E. P., 1997, Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: A closer look. Biochemistry, 79, 567-575.
16. Franken, N. A. P., Can Bree, C., Kipp, J. B. A. and Barendsen, G. W., 1997, Modification of potentially lethal damage in irradiated Chinese hamster V79 cells after incorporation of halogenated pyrimidines. International Journal of Radiation Biology, 72, 101-109.
17. Franken, N. A. P., Ruurs, P., Ludwicknow, G., Can Bree, C., Kipp, J. B. A., Darroundi, F. and Barendsen, G. W., 1999, Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and high dosed of radiation and sensitization by iododeoxyuridine in human SW-1573 cells. Internal Journal of Radiation Biology, 75, 293-299.
18. Frankenberg-Schwager, M. and Frankenberg, D., 1990, DNA double-strand breaks: Their repair and relationship to cell killing in yeast. International Journal of Radiation Biology, 58, 569-575.
19. Fuciarelli, F., Sisk, E. C. and Zimbrick, J. D., 1994, Electron migration in oligonucleotides upon γ-irradiation in solution. International Journal of Radiation Biology, 65, 409-418.
20. Furusawa, Y., Maezawa, H. and Suzuki, K. 1991, Enhanced killing of 5-bromodeoxyuridine labelled bacteriophage T1 by monochromatic synchrotron X-ray at the energy of bromine K-shell absorption edge. Journal of Radiation Research, 32, 1-12.
21. Goodhead, D. T., 1994, Initial events in the cellular effects of ionising radiations; clustered damage in DNA. International Journal of Radiation Biology, 65, 7-17.
22. Hissung A., Von Sonntag, C., Veltiwisch, D. and Asmus, K. D., 1981, The reaction of the 2′-deoxyadenosine electron adduct in aqueous solution. The effects of the radiosensitizer p-nitroacetophenone. A pulse spectroscopic and pulse conductometric study. International Journal of Radiation Biology, 39, 63-71.
23. Humm, J. L. and Charlton, D. E., 1988, Double strand breakage in DNA produced by the photoelectric interaction with incorporated 'cold' bromine. In K. F. Baverstock and D. E. Charlton (eds), DNA Damage by Auger Emitters (London: Taylor & Francis), pp. 111-122.
24. Iliakis, G. and Kurtzman, S., 1991, Mechanism of radiosensitization by halogenated pyrimidines: Bromodeoxyuridine and B-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateauphase Chinese hamster ovary cells. Radiation Research, 127, 45-51.
25. Iliakis, G., Kurtzman, S., Pantelias, G. and Okayasu, R., 1989, Mechanism of radiosensitization by halogenated pyrimidines; effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing. Radiation Research, 119, 286-304.
26. Iliakis, G., Pantelias, G. and Kurtzman, S., 1992, Mechanism of radiosensitization by halogenated pyrimidines: Effect of BrdU on cell killing and interphase chromosome breakage in radiation-sensitive cells. Radiation Research, 129, 202-211.
27. Iliakis, G., Wright, E. and Ngo, Q. H., 1987a, Possible importance of PLD repair in the modulation of BrdUrd and IdUrd-mediated radiosensitization in plateau-phase C3H10T1/2 mouse embryo cells. International Journal of Radiation Biology, 51, 541-548.
28. Iliakis, G., Wright, E. and Ngo, Q. H., 1987b, Repair and fixation of potentially lethal damage (PLD) as demonstrated by delayed plating or incubation with araA in contact inhibited refed plateau-phase C3H mouse embryo 10T1/2 cells grown in the presence of BrdUrd. Radiation Environmental Biophysics, 26, 47-62.
29. Jones, G. D. D., Ward, J. F., Limoli, G. L., Move, D. E. and Ling, L. L., 1995, Mechanisms of radiosensitization in iododeoxyuridine-substituted cells. International Journal of Radiation Biology, 67, 647-653.
30. Karnas, S. J., Yu, E. McGarry, R. C. and Battista, J. J., 1999, Optimal photon energies for IUdR K-edge radiosensitization with filtered x-ray and radioisotope sources. Physics in Medicine and Biology, 44, 2537-2549.
31. Kellerer, M. K., 1971, Consideration on the random traversal of convex bodies and solutions for general cylinders. Radiation Research, 47, 359-376.
32. Kinsella, T. J., Mitchell, J. B., Russo, A., Aiken, M., Morstyn, G., Hsu, S. M., Rowland, J. and Glatstein, E., 1984, Continuous intravenous infusions of bromodeoxyuridine as a clinical radiosensitizer. Journal of Clinical Oncology, 2, 1144-1150.
33. Larson, D., Bodell, W. J., Lang, C., Philips, T. L., Schell, M., Sherieve, D. and Troxel, T., 1989, Auger electron contribution to bromodeoxyuridine cellular radiosensitization. International Journal of Radiation Oncology, Biology, Physics, 30, 171-176.
34. Lawrence, T. S., Davis, M. A. and Normolle, D. P., 1995, Effect of bromodeoxyuridine on radiation-induced DNA damage and repair based on DNA fragment size using pulsed-field gel electrophoresis. Radiation Research, 144, 282-287.
35. Lemaire, D. G. E., Bothe, E. and Schulte-Frohlinde, D., 1984, Yields of radiation-induced main chain scission of poly U in aqueous solution: Strand break formation via base radicals. International Journal of Radiation Biology, 45, 351-381.
36. Lett, J. T., Parkins, G. and Alexander, P., 1964, Mechanisms of sensitization to X-rays of mammalian cells by 5-bromodeoxyuridine. Nature, 203, 593-596.
37. Ling, L. and Ward, J. F., 1990, Radiosensitization of Chinese hamster C79 cells by bromodeoxyuridine substitution of tymidine: Enhancement of radiation-induced toxicity and DNA strand break production by monofilar and bifilar substitution. Radiation Research, 121, 76-83.
38. Linstadt, D., Blakely, E., Philips, T. L. and Castro, J. R., 1988, Radiosensitization produced by iododeoxyuridine with high linear energy transfer heavy ion beams, International Journal of Radiation Oncology, Biology, Physics, 15, 703-710.
39. Maezawa, H., Hieda, K., Kobayashi, K. and Ito, T., 1988, Effect of Auger cascades of bromine induced by K-shell photoabsorption on plasmid DNA, bacteriophages, E. coli and yeast cells. In K. F. Baverstock and D. E. Charlton (eds), DNA Damage by Auger Emitters (London: Taylor & Francis), pp. 135-146.
40. 60Co γ-irradiation and to low-energy X radiation by bromouracil. Radiation Research, 69, 152-165.
41. Miller, E. M., Fowler, J. F. and Kinsella, T. J., 1992a, Linear-quadratic analysis of radiosensitization by halogenated pyrimidines I. Radiosensitization of human colon cancer cells by iododeoxyuridine. Radiation Research, 131, 81-89.
42. Miller, E. M., Fowler, J. F. and Kinsella, T. J., 1992b, Linear-quadratic analysis of radiosensitization by halogenated pyrimidines II. Radiosensitization of human colon cancer cells by bromodeoxyuridine. Radiation Research, 131, 90-107.
43. Miller, R. W., Degraff, W., Kinsella, T. J. and Mitchell, J. B., 1987, Evaluation of incorporated iododeoxyuridine cellular radiosensitization by photon activation therapy. International Journal of Radiation Oncology, Biology, Physics, 13, 1193-1197.
44. Nath, R., Bongiorni, P. and Rockwell, R., 1987, Enhancement of IUdR radiosensitization by low energy photons. International Journal of Radiation Oncology, Biology, Physics, 13, 1071-1079.
45. Nese, C., Yuan, Z., Schuchmann, M. N. and Von Sonntag, C., 1992, Electron transfer from nucleobase electron adducts to 5-bromouracil. Is guanine an ultimate sink for the electron in irradiated DNA? International Journal of Radiation Biology, 62, 527-541.
46. Nikjoo, H., Bolton, C. E., Watanabe, R., Terrisol, M., O'Neill, P. and Goodhead, D. T., 2002, Computational modelling of DNA damage induced by energetic electrons 100eV to 100keV. Radiation Protection Dosimetry, 99, 77-80.
47. Nikjoo, H., Goodhead, D. T., Charlton, D. E. and Paretzke, H. G., 1991, Energy deposition in small cylindrical targets by monoenergetic electrons. International Journal of Radiation Biology, 60, 739-756.
48. 125I. Acta Oncologica, 35, 849-856.
49. Nikjoo, H., O'Neill, P., Goodhead, D. T. and Terrissol, M., 1997, Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events. International Journal of Radiation Biology, 71, 467-483.
50. Nikjoo, H., O'Neill, P., Terrissol, M. and Goodhead, D. T., 1999, Quantitative modelling of DNA damage using Monte Carlo track structure method. Radiation and Environmental Biophysics, 38, 31-38.
51. Nikjoo, H., O'Neill, P., Wilson, W. E. and Goodhead, D. T., 2001, Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiation Research, 156, 577-583.
52. Nikjoo, H., Terrissol, M., Hamm, R. N., Turner, J. E., Uehara, Paretzke, H. G. and Goodhead, D. T., 1994, Track structure approaches to the interpretation of radiation effects on DNA. Radiation Protection Dosimetry, 52, 165-169.
53. Olive, P. L., 1998, The role of DNA single- and double-strand breaks in cell killing by ionizing radiation. Radiation Research, 150, S42-S51.
54. Rahn, R. O. and Sellin, H. G., 1982, Photolysis of iododeoxycytidine in DNA and related model systems: Evidence for short-range energy transfer. Photochemistry and Photobiology, 23, 313-137.
55. Saenger, W., 1984, Principles of Nucleic Acid Structure (New York: Springer).
56. Smoluchowski, M. V., 1916, Deri vortrage uber diffusion, brownsche molekularbewegung und koagulation von kolloidteilchen. Physikalische Zeitschrift, 17, 557-565.
57. Terrissol, M, 1994, Modelling of radiation damage by 125I on a nucleosome. International Journal of Radiation Biology, 66, 447-451.
58. Umrania, Y., Nikjoo, H. and Goodfellow, J. M., 1995, A knowledge-based model of DNA hydration. International Journal of Radiation Biology, 67, 145-152.
59. Van Lith, D., Warnab, J. M., De Haas, M. P. and Hummel, A., 1986, Electron migration in hydrated DNA and collagen at low temperatures. Part I. Effect of water concentration. Journal of the Chemical Society, Faraday Transactions, 82, 2933-2943.
60. Von Sonntag, C., 1987, The Chemical Basis of Radiation Biology (London: Taylor & Francis).
61. Wang, Y. and Iliakis, G., 1987, Effects of 5′-iododeoxyuridien on the repair of radiation induced potentially lethal damage interphase chromatin breaks and DNA double strand breaks in Chinese hamster ovary cells. International Journal of Radiation Oncology, Biology, Physics, 23, 353-360.
62. Wang, Y., Pantelias, G. E. and Iliakis, G., 1994, Mechanisms of radiosensitization by halogenated pyrimidines: The contribution of excess DNA and chromosome damage in BrdU radiosensitization may be minimal in plateau-phase cells. International Journal of Radiation Biology, 66, 133-142.
63. Ward, J. F., 1994, The complexity of DNA damage: Relevance to biological consequences. International Journal of Radiation Biology, 66, 427-432.
64. Webb, C. F., Jones, G. D. D., Ward, J. F., Moyer, D. J., Aguilera, J. A. and Ling, L. L., 1993, Mechanisms of radiosensitization in bromodeoxyuridine-substituted cells. International Journal of Radiation Biology, 64, 695-705.
65. Zimbrick, J. D., Ward, J. F. and Myers, L. S., Jr, 1969a, Studies on the chemical basis of cellular radiosensitization by 5-bromouracil substitution in DNA. I. Pulse- and steady-state radiolysis of 5-bromouracil and thymine. International Journal of Radiation Biology, 16, 505-523.
66. Zimbrick, J. D., Ward, J. F. and Myers, L. S., Jr, 1969b, Studies on the chemical basis of cellular radiosensitization by 5-bromouracil substitution in DNA. II. Pulse- and steadystate radiolysis of bromouracil-substituted and unsubstituted DNA. International Journal of Radiation Biology, 16, 524-534.