Tumor necrosis factor receptor type II (exon 6) and interleukin-6 (-174) gene polymorphisms are not associated with family history but tumor necrosis factor receptor type II is associated with hypertension in patients with rheumatoid arthritis from Northern Sweden

Arthritis and Rheumatism

Volumn 46, Issue 11, 2002, Pages 3096-3098

  Dahlqvist, Solbritt Rantapää ^a   Ärlestig, Lisbeth ^a   Sikström, Carin ^a   Linghult, Solveig ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GENOMIC DNA; HLA DR ANTIGEN; INTERLEUKIN 6; TUMOR NECROSIS FACTOR RECEPTOR 2;

ADULT; AGED; ARTHRITIS; ARTICLE; COMORBIDITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENE FREQUENCY; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; RHEUMATOID ARTHRITIS; SWEDEN;

ARTHRITIS, RHEUMATOID; EXONS; FEMALE; HUMANS; HYPERTENSION; INTERLEUKIN-6; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, TUMOR NECROSIS FACTOR; SWEDEN;

EID: 0036847121     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10592     Document Type: Article

References (12)

1. Jawaheer D, Gregersen PK. The genetic components of rheumatoid arthritis. In: Nepom GT, editor. Rheumatic disease Clinics of North America. Philadelphia: Saunders; 2002. p. 1-15.
2. Weyand CM, Klimiuk PA, Goronzy JJ. Heterogeneity of rheumatoid arthritis: From phenotypes to genotypes. Springer Semin Immunopathol 1998;20:5-22.
3. Cvetkovic JT, Wållberg-Jonsson S, Stegmayr B, Rantapää-Dahlqvist S, Lefvert AK. Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-α IL-1β, and IL-1Ra genes. J Rheumatol 2002;29:212-9.
4. Cornelis F, Faure S, Martinez M, Prud'homme JF, Fritz P, Dib C, et al. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci U S A 1998;95:10746-50.
5. Shiozawa S, Hayashi S, Tsukamoto Y, Goko H, Kawasaki H, Wada T, et al. Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol 1998;10:1891-5.
6. Barton A, John S, Ollier WER, Silman A, Worthington J. Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians. Arthritis Rheum 2001;44:61-5.
7. Dieude P, Petit E, Cailleau-Moindrault S, Osorio J, Prum B, Lasbleiz S, et al. Association between TNFR2 and familial but not sporadic rheumatoid arthritis provides evidence for genetic heterogeneity. Arthritis Rheum 2001;44 Suppl 9:S179.
8. Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, Humphries S, et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998;102:1369-76.
9. Pascual M, Nieto A, Mataran L, Balsa A, Pascual-Salcedo D, Martin J. IL-6 promotor polymorphisms in rheumatoid arthritis. Genes Immun 2000;1:338-40.
10. Shibue T, Tsuchiya N, Komata T, Matsushita M, Shiotra M, Ohashi J, et al. Tumor necrosis factor α 5′-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. Arthritis Rheum 2000;43:753-7.
11. Glenn CL, Wang WYS, Benjafield AV, Morris BJ. Linkage and association of tumor necrosis factor receptor 2 locus with hypertension, hypercholesterolemia and plasma shed receptor. Hum Mol Genet 2000;9:1943-9.
12. Wållberg-Jonsson S, Johansson H, Ohman ML, Rantapaa-Dahlqvist S. Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis: A retrospective cohort study from disease onset. J Rheumatol 1999;26:2562-71.