Visceral sensitivity in gastroesophageal reflux

Digestive Diseases and Sciences

Volumn 47, Issue 11, 2002, Pages 2554-2564

  Theodoropoulos, Demetrios S ^a   Pecoraro, Donna L ^b   Lockey, Richard F ^b   Boyce Jr , H Worth ^b   Bukantz, Samuel C ^b  

^a Saint Joseph's Hospital Wisconsin   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Allergy; Gastroesophageal reflux; Neurogenic inflammation; Pain

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ESOPHAGUS PH; FEMALE; GASTROESOPHAGEAL REFLUX; HEARTBURN; HUMAN; MAJOR CLINICAL STUDY; MALE; PERCEPTION; PRIORITY JOURNAL; REFLUX ESOPHAGITIS; RETROSTERNAL PAIN; SCORING SYSTEM;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; GASTROESOPHAGEAL REFLUX; HEARTBURN; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN THRESHOLD; VISCERA;

EID: 0036846656     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020528613756     Document Type: Article

References (36)

1. Nebel OT, Fornes MF, Castell DO: Symptomatic gastroesophageal reflux: Incidence and precipitating factors. Am J Dig Dis 21:953-956, 1976
2. Castell DO., Greenberger NJ: A practical approach to heartburn. Hospital Pract 00;89-98, 1999
3. Johanessen T, Petersen H, Kleveland PM, Dybdahl JH, Sandvik AK, Brenna E, et al: The predictive value of history in dyspepsia. Scand J Gastroenterol 25:687-689, 1990
4. Berstad A, Hatlebakk JG: The predictive value of symptoms in gastro-oesophgeal reflux disease. Scand J Gastroenterol Suppl 211:1-4, 1995
5. Koufman JA: The otolaryngologic manifestations of gastroesophageal reflux disease: A clinical investigation of 225 patients using ambulatory 24-hr pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope 101 (suppl 53):1-78, 1991
6. Champion GL, Richter JE: Atypical presentations of gastroesophageal reflux disease: Chest pain, pulmonary and ear, nose, throat manifestations. Gastroenterologist 1:18-23, 1993
7. Harding S: Gastroesophageal reflux disease, airway disease and the mechanisms of interaction, in Gastroesohageal Reflux Disease and Airway Disease. MR Stein (ed). New York, Marcel Dekker, pp 139-178, 1999
8. Theodoropoulos DS, Lockey RF, Rodriguez JA, Boyce HW Jr, Johnson MC, Ledford DK: Upper respiratory symptoms in patients with gastroesophageal reflux (abstract). Am J Respir Crit Care Med 159(suppl. 3):A123, 1999
9. Theodoropoulos DS, Ledford DK, Lockey RF, Pecoraro DL, Rodriguez JA, Johnson MC, Boyce HW Jr: Upper airway symptoms in gastroesophageal reflux disease. J Allergy Clin Immunol 105(suppl. 1):S72, 2000 (abstract)
10. Theodoropoulos DS, Lockey RF, Bukantz SC, Boyce HW Jr. Gastroesophageal reflux and asthma: A review of pathogenesis, diagnosis and therapy. Allergy 54:651-661, 1999
11. Theodoropoulos DS, Lockey RF, Boyce HW Jr. Sandifer syndrome and gastroesophageal reflux disease. J Neurol Neurosurg Psychiatry 66:805-806, 1999
12. Kennedy JH. "Silent" gastroesophageal reflux: An important but little known cause of pulmonary complications. Dis Chest 42:42-45, 1962
13. Trimble KC, Pryde A, Heading RC: Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: Evidence for a spectrum of visceral sensitivity in GORD. Gut 37:7-12, 1995
14. Trimble KC, Douglas S, Pryde A, Heading RC: Clinical characteristics and natural history of symptomatic but not excess gastroesophageal reflux. Dig Dis Sci 40:1098-1104, 1995
15. Theodoropoulos DS, Ledford DK, Lockey RF, Pecoraro DL, Rodriguez JA, Johnson MC, Boyce HW Jr: Prevalence of upper respiratory symptoms in patients with gastroesophageal reflux disease. Am J Respir Crit Care Med 164:72-76, 2001
16. Johnson LF., DeMeester TR. Twenty-four-hour pH monitoring of the distal esophagus. Am J Gastroenterol 62:325-332, 1974
17. Dobhan R., DeNuna S, Castell DO. Ambulatory prolonged pH monitoring of the proximal esophagus. How much acid exposure is normal? Gastroenterology 100(suppl A2):825, 1991
18. Dobhan R., Castell DO. Prolonged esophageal pH monitoring: A comparison between 24 hour and 16 hour overnight monitoring. Gastroenterology 100(Suppl A2):825, 1991
19. Theodoropoulos DS, Ledford DK, Lockey RF, Pecoraro DL, Rodriguez JA, Johnson MC, Boyce HW Jr: Gastroesophageal reflux associated symptom scores correlate with numbers of reflux episodes. J Allergy Clin Immunol 107(suppl. 2):S49, 2001
20. Ing A., Ngu MC, Breslin AB. Chronic persistent cough and clearance of esophageal acid. Chest 102:1668-1671, 1992
21. Campos GM, Peters JH, DeMeester TR, Oberg S, Crookes PF, Mason RJ. The pattern of esophageal acid exposure in gastroesophageal reflux disease influences the severity of the disease. Arch Surg 134:882-887, 1999
22. Mittal RK, McCallum RW: Characteristics and frequency of transient relaxations of the lower esophageal sphincter in patients with reflux esophagitis. Gastroenterology 95:593-599, 1988
23. Sifrim D, Tack J, Lerut T, Janssens J: Transient lower esophageal sphincter relaxations and esophageal body muscular contractile response in reflux esophagitis. Dig Dis Sci 45:1293-1300, 2000
24. Hamamoto J., Kohrogi H, Kawano O, Iwagoe H, Fujii K, Hirata N, Ando M. Esophageal stimulation by hydrochloric acid causes neurogenic inflammation in the airways in guinea pigs. J Appl Physiol 82:738-745, 1997
25. Herve P, Denjean A, Jian R: Intraesophageal perfusion of acid increases the bronchomotor response to methacholine and to isocapnic hyperventilation in asthmatic subjects. Am Rev Respir Dis 134:986-989, 1986
26. Janiszewski J., Bienenstock J, Blennerhasset MG. Picomolar doses of substance P trigger electrical responses in mast cells without degranulation. Am J Physiol 267:C138-C145, 1994
27. Theodoropoulos DS, Ledford DK, Lockey RF. Expression of the lung-specific thyroid transcription factor (TTF-1) within the tracheoesophageal fistula of embryo rats exposed to adriamycin. J Pediatr Surg 35:811-812, 2000
28. Holgate ST: Airways remodelling: The chronicity of asthma, Quaeritur Focus VIII. Eur Respir Rev 8:1007-1011, 1998
29. Lorentz A, Schwengberg S, Mierke C, Manns MP, Bischoff SC: Human intestinal mast cells produce IL-5 in vitro upon IgE receptor cross-linking and in vivo in the course of intestinal inflammatory disease. Eur J Immunol 29:1496-503, 1999
30. Tummala V, Barwick KW, Sontag SJ, Vlahcevic RZ, McCallum RW: The significance of intraepithelial eosinophils in the histologic diagnosis of gastroesophageal reflux. Am J Clin Pathol 87:43-48, 1987
31. Wang HH, Mangano MM, Antonioli DA: Evaluation of T-lymphocytes in esophageal mucosal biopsies. Mod Pathol 7:55-58, 1994
32. Ruchelli E, Wenner W, Voytek T, Brown K, Liacouras C: Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy. Pediatr Dev Pathol 2:15-18, 1999
33. Liacouras CA, Wenner WJ, Brown K, Ruchelli E: Primary eosinophilic esophagitis in children: Successful treatment with oral corticosteroids. J Pediatr Gastroenterol Nutr 26:380-385, 1998
34. Walsh SV, Antonioli DA, Goldman H, Fox VL, Bousvaros A, Leichtner AM, Furuta GT: Allergic esophagitis in children: A clinicopathological entity. Am J Surg Pathol 23:390-396, 1999
35. Mishra A, Hogan SP, Brandt EB, Rothenberg ME: An etiological role for aeroallergens and eosinophils in experimental esophagitis. J Clin Invest 107:83-90, 2001
36. Canning BJ: Inflammation in asthma. In Gastroesophageal Reflux Disease and Airway Disease. MR Stein (ed). Inc. New York, Marcel Dekker, pp 19-54, 1999