Evaluation of whole blood serotonin and plasma and urine 5-hydroxyindole acetic acid in diagnosis of carcinoid disease

Annals of Clinical Biochemistry

Volumn 39, Issue 6, 2002, Pages 577-582

  Carling, R S ^a   Degg, T J ^a   Allen, K R ^a   Bax, N D S ^b   Barth, J H ^a  

^a LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^b ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; SEROTONIN;

ADULT; AGED; ARTICLE; CARCINOID; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ENTEROCHROMAFFIN CELL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PATIENT MONITORING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEROTONIN BLOOD LEVEL; THROMBOCYTE; URINE LEVEL; ADOLESCENT; BLOOD; CHILD; MIDDLE AGED; REPRODUCIBILITY; URINE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOID TUMOR; CHILD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; HYDROXYINDOLEACETIC ACID; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEROTONIN;

EID: 0036846366     PISSN: 00045632     EISSN: None     Source Type: Journal    
DOI: 10.1258/000456302760413351     Document Type: Article

References (10)

1. Williams ED, Sandler N. The classification of carcinoid tumours. Lancet 1963; i: 238-9
2. Newton JN, Swerdlow AJ, dos Santos Silva IM, Vessey MP, Grahame-Smith DG, Primatesta P, et al. The epidemiology of carcinoid tumours in England and Scotland. Br J Cancer 1994; 70: 939-42
3. Cheek RC, Wilson H. Carcinoid tumours. Curr Prob Surg 1970; 7: 4-31
4. Thorson G, Bjork G, Bjorkman G. Malignant carcinoid of the small intestine with metastasis to liver, valvular disease of the right side of the heart (pulmonary stenosis and tricuspid regurgitation without septal defects), peripheral vasomotor symptoms, bronchoconstriction and an unusual type of cyanosis. Am Heart J 1954; 47: 795-817
5. Meijer W, Kema I, Volmer M, Willemse P, de Vries E. Discriminating capacity of indole markers in the diagnosis of carcinoid tumours. Clin Chem 2000; 46: 1588-96
6. Degg TJ, Allen KR, Barth JH. Measurement of plasma 5-hydroxyindoleacetic acid in carcinoid disease: An alternative to 24-hour urine collections? Ann Clin Biochem 2000; 37: 724-6
7. Kwarts E, Kwarts J, Rutger HA. A simple paired ion liquid chromatography assay for serotonin in cerebrospinal fluid, platelet rich plasma and urine. Ann Clin Biochem 1984; 21: 425-9
8. Skrinska V, Hahn S. High performance liquid chromatography of 5-hydroxyindole-3-acetic acid in urine with direct sample injection. J Chromat 1984; 311: 380-4
9. Tormey WP, Fitzgerald RJ. The clinical and laboratory correlates of an increased urinary 5-hydroxyindoleacetic acid. Postgrad Med J 1995; 71: 542-5
10. Ruszniewski P, Ducreux M, Chayvialle JA, Blumberg J, Cloarec D, Michel H, et al. Treatment of the carcinoid syndrome with the long-acting somatostatin analogue lanreotide: A prospective study in 39 patients. Gut 1996; 2: 279-83