Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes

International Journal of Antimicrobial Agents

Volumn 20, Issue 5, 2002, Pages 348-360

  Hall, Iris H ^a   Schwab, Ute E ^b   Stacy Ward, E ^a   Butts, John D ^c   Wolford, Eric T ^d   Ives, Timothy J ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c University of Kentucky   (United States)

^d GLAXOSMITHKLINE   (United States)

Author keywords

Azithromycin; LPS; THP 1 monocytes

Indexed keywords

AZITHROMYCIN; BACTERIUM LIPOPOLYSACCHARIDE; CATHEPSIN; ENZYME PRECURSOR; HYDROGEN PEROXIDE; HYDROLASE; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; N ACETYLGLUCOSAMINE; NITRIC OXIDE; PROTEIN KINASE C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUCROSE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; CARBON; MICROSPHERE;

ACIDITY; ACTIVE TRANSPORT; ARTICLE; BACTERICIDAL ACTIVITY; CELL ORGANELLE; CELL PH; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG UPTAKE; ENZYME ACTIVITY; FETAL CALF SERUM; HUMAN; HUMAN CELL; MONOCYTE; PASSIVE TRANSPORT; PHAGOCYTOSIS; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; ULTRACENTRIFUGATION; CELL LINE; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PH; RESPIRATORY BURST; TIME;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CARBON RADIOISOTOPES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSPHERES; MONOCYTES; PHAGOCYTOSIS; RESPIRATORY BURST; TIME FACTORS;

EID: 0036845780     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(02)00187-5     Document Type: Article

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