Effect of cogent db, a herbal drug, on plasma insulin hepatic enzymes of glucose metabolism in experimental diabetes

Diabetes, Obesity and Metabolism

Volumn 4, Issue 6, 2002, Pages 394-398

  Saravanan, G ^a   Pari, L ^a   Venkateswaran, S ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

6 biphosphatase; Alloxan diabetes; Cogent db; Fructose 1; Glucose 6 phosphotase; Hepatic enzymes; Hexokinase; Plasma insulin

Indexed keywords

ALLOXAN; COGENT DB; FRUCTOSE BISPHOSPHATASE; GLIBENCLAMIDE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HERBACEOUS AGENT; HEXOKINASE; INSULIN; LIVER ENZYME; SODIUM CHLORIDE; SUGAR; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET RESTRICTION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REGULATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE URINE LEVEL; GLYCOLYSIS; INSULIN BLOOD LEVEL; LIVER; MALE; NONHUMAN; PANCREAS; RAT; RAT STRAIN;

EID: 0036845649     PISSN: 14628902     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1463-1326.2002.00233.x     Document Type: Article

References (26)

1. Zimmerman BR, Espenshade J, Fujimoto WY. The pharmacological treatment of hyperglycemia in NIDDM. Diabetes Care 1996; 19 (Suppl. 1): 54-64.
2. Bailey CJ. Potential new treatment for type 2 diabetes. Trends in pharmacological science. 2000; 21: 259-265.
3. Olajide AO, Awe SO, Makinde JM, Morebise O. Evaluation of the anti-diabetic property of Morinda lucida leaves in streptozotocin diabetic rats. J Pharm Pharmacol 1999; 51: 1321-1324.
4. Mitra SK, Gopumadhavan S, Muralidhar TS, Anturlikar SD, Sujatha MB. Effect of a herbomineral preparation D-400 in streptozotocin-induced diabetic rats. J Ethnopharmacol 1996; 54: 41-46.
5. Pari L, Umamaheswari J. Antihyperglycaemic activity of Musa sapientum flowers. Effect of lipid peroxidation in alloxan diabetic rats. Phytother Res 2000; 14: 1-3.
6. Bailey CJ, Day C. Traditional treatments for diabetes. Diabetes Care 1989; 12: 553-564.
7. The WHO Expert Committee on Diabetes Mellitus. Technical Report Series 646, Geneva, World Health Organization, 1980.
8. Santhosh kumari KS, Devi KS. Effect of indigenous drugs on glucuronoglycan metabolism in diabetic hypertensive rabbits. Ind J Exp Biol 1993; 31: 595-599.
9. Bhattacharya SK, Satyam KS, Chakrabarti A. Effect of Trasina, an ayurvedic herbal formulation, on pancreatic islet superoxide dismutase activity in hyperglycemic rats. Ind J Exp Biol 1997; 35: 297-299.
10. Chattopadhyay RR. Possible mechanism of antihyperglycemic effect of Azardirachta indica leaf extracts. J Ethnopharmacol 1999; 67 (3): 373-376.
11. Prince PSM, Menon VP, Pari L. Hypoglycaemic activity of Syzigium cumini seeds: effect on lipid peroxidation in alloxan diabetic rats. J Ethnopharmacol 1998; 61: 1-7.
12. Sharma RD. Effect of fenugreek seed and leaves on blood glucose and serum insulin response in human subjects. Nutr Res 1986; 6: 1353-1364.
13. Pari L, Saravanan G. Antidiabetic effect of cogent db, a herbal drug in alloxan induced diabetes. Comp Biochem Physiol 2002; 131: 19-25.
14. Prince PSM, Menon VP. Hypoglycaemic and other related actions of Tinaspora cordifolia roots in alloxan-induced diabetic rats. J Ethnopharmacol 2000; 70: 9-15.
15. Waynforth BH. Injection Techniques, Experimental and Surgical Techniques in the Rat. London: Academic Press, 1980: 3-61.
16. Sasaki T, Matsy S, Sonace A. Effect of acetic acid concentration on the colour reaction in the O-toluidine boric acid method for blood glucose estimation. Rinsho kagaku 1972; 1: 346-353.
17. Brandstrup N, Kirk JE, Bruni C. The hexokinase and phophoglucoisomerase activities of aortic and pulmonary artery tissue in individuals of various ages. J Gerantol 1957; 12: 166-171.
18. Kode H, Oda T. Pathological occurrence of glucose-6-phosphatase in serum in liver diseases. Clin Chem Acta 1959; 4: 554-561.
19. Gancedo JM, Gancedo C. Fructose- 1,6-bisphosphatase, phosphofructokinase and glucose-6-phosphatase dehydrogenase from fermenting and non-fermenting yeasts. Arch Microbiol 1971; 76: 132-138.
20. 3-adrenergic agonist on lipid metabolism in alloxandiabetic rats. J Pharm Pharmacol 2000; 52: 851-856.
21. Gupta D, Raju J, Jaya prakash R, Baquar NZ. Change in the lipid profile, lipogenic and related enzymes in the liver of experimental diabetic rats: effect on insulin and vanadate. Diab Res Clin Prac 1999; 46: 1-7.
22. Seifter S, England S. In Arias I, Popper H, Schacter D. et al. eds. The Liver: Biology and Pathobiology. New York: Raven Press, 1982: 219-249.
23. Baquer NZ. Glucose overutilization and under utilization in diabetes and effects of antidiabetic compounds. Real Acad Farm (Spain) 1998; 64: 147-180.
24. Grover JK, Vats V, Rathi SS. Antihyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000; 73: 461-470.
25. Shibib BA, Khan LA, Rahman R. Hypoglycaemic activity of Coccinia indiaca and Mamordica charantia in diabetic rats, depression of hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose- 1,6-bisphosphatase and elevation of both liver and red cell shunt enzyme glucose-6-phosphate dehydrogenase. Biochem J. 1993; 291 (1): 267-270.
26. Baquer NZ, Gupta D, Raju J. Regulation of metabolic pathways in liver and kidney during experimental diabetes: effects of antidiabetic compounds. Ind J Clin Biochem 1998; 13 (2): 63-80.