Screening of eight alkaloids and ten flavonoids isolated from four species of the genus Boronia (Rutaceae) for antimicrobial activities against seventeen clinical microbial strains

Phytotherapy Research

Volumn 16, Issue 7, 2002, Pages 672-674

  Nazrul Islam, S K ^a   Gray, Alexander I ^b   Waterman, Peter G ^b   Ahasan, M ^b  

^a UNIVERSITY OF DHAKA   (Bangladesh)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Alkaloids; Antimicrobial activities; Boronia; Flavonoids; Rutaceae

Indexed keywords

1 HYDROXY 10 METHYL 9(10H) ACRIDINONE; 1 METHYL 2 NONYL 4 QUINOLONE; 1,7 DIHYDROXY 9(10H) ACRIDINONE; 1,8 DIHYDROXY 10 METHYL 9(10H) ACRIDINONE; 1,8 DIHYDROXY 3 METHOXY 9 ACRIDINONE; 2 NONYL 4 QUINOLONE; 2,3 DIMETHYL 4 QUINOLONE; 3,4',5' TRIHYDROXY 7 (3,7 DIMETHYLOCTA 2,6 DIENYLOXY)FLAVONE; 3,5,7 TRIHYDROXY 8 METHOXY 4' (3 METHYLBUT 2 ENYLOXY)FLAVONE; 4',5 DIHYDROXY 3,3',6 TRIMETHOXY 7 (3 METHYLBUT 2 ENYLOXY)FLAVONE; 4',5 DIHYDROXY 3,3',8 TRIMETHOXY 7 (3 METHYLBUT 2 ENYLOXY)FLAVONE; 5,4' DIHYDROXY 3,7,8,3' TETRAMETHOXYFLAVONE; 5,7 DIHYDROXY 3 METHOXY 4' (3 METHYLBUT 2 ENYLOXY)FLAVONE; ACRIDONE DERIVATIVE; ALKALOID DERIVATIVE; AMPICILLIN; FLAVONOID; NATURAL PRODUCT; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BORONIA; DRUG ISOLATION; DRUG SCREENING; ESCHERICHIA COLI; KLEBSIELLA; MEDICINAL PLANT; MICROCOCCUS LUTEUS; NONHUMAN; RUTACEAE; SALMONELLA TYPHI; STAPHYLOCOCCUS AUREUS;

ALKALOIDS; AMPICILLIN; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIA; ESCHERICHIA COLI; FLAVONOIDS; HUMANS; KLEBSIELLA; MICROBIAL SENSITIVITY TESTS; PHYTOTHERAPY; PLANT EXTRACTS; RUTACEAE; SALMONELLA TYPHI; SARCINA; STAPHYLOCOCCUS AUREUS;

BACILLUS SUBTILIS; BORONIA; ESCHERICHIA COLI; KLEBSIELLA; KLEBSIELLA SP.; MICROCOCCUS LUTEUS; RUTACEAE; SALMONELLA; SALMONELLA TYPHI; SARCINA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0036845636     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.999     Document Type: Article

References (17)

1. Ahsan M, Chowdhury AKA, Islam SN, Ahmed ZU. 1996. Garlic extract and allicin: A broad spectrum antibacterial agent effective against multiple drug resistant strain of Shigella dysenterie type 1, Shigella flexneri, enterotoxigenic Escherichia coli and Vibrio cholerae. Phytother Res 10: 329.
2. Ahsan M, Gray AI, Leach G, Waterman PG. 1993. Quinolone and acridone alkaloids from Boronia lanceolata. Phyto-chemistry 33: 1507.
3. Ahsan M, Gray AI, Waterman PG. 1994a. 4-Quinolinone, 2-quinolinone, 9-acridanone and furoquinoline alkaloids from the aerial parts of Boronia bowmanii. J Nat Prod 57: 670.
4. Ahsan M, Armstrong JA, Gibbons S, Gray AI, Waterman PG. 1994b. Novel O-prenylated flavonoids from two varieties of Boronia caerulescens. Phytochemistry 37: 259.
5. Ahsan M, Gray Al, Waterman PG. 1994c. Farnesyl acetophenone and flavanone compounds from the aerial parts of Boronia ramosa. J Nat Prod 57: 673.
6. Bauer AW, Kirby WMM, Sherries JC, Truck M. 1966. Antibiotic susceptibility testing by a standardized single disc method. Am J Clin Pathol 45: 493.
7. Chan JA, Shultis EA, Carr SA et al. 1989. Novel phoroglucinols from the plant Meliocope Seeilifforo (Rutaceae). J Org Chem 54: 2098.
8. Chowdhury AKA, Ahsan M, Islam SN, Ahmed ZU. 1991. Efficacy of aqueous extract of garlic and allicin in experimental shigellosis in rabits. Indian J Med Res [A] 93: 33.
9. Ferdous AJ, Ahsan M, Islam SN, Hasan CM, Ahmed ZU. 1992. In vitro antibacterial activity of the volatile oil of Nigella sativa seeds against multiple drug resistant isolates of Shigella spp and isolates of V. cholerae and E. coli. Phytother Res 6: 137.
10. Gonzalez AG, Darias V, Alonsa G, Baoda JN, Feria M. 1978. Cytostatic activity of sesquiterpene lactone from Compositae of the Canary Islands. Planta Med33: 356.
11. Islam SN, Ahsan M. 1997. Biological activities of the secondary metabolites isolated from Zieria smithii and Zanthoxylum elephantiasis on microorganism and brine shrimps. Phytother Res 11: 64.
12. Islam SN, Ferdous AJ, Ahsan M, Faroque ABM. 1990. Antibacterial activity of clove extracts against pathogenic strains including clinically resistant isolates of Shigella and Vibrio cholerae. Pakistan J Pharm Sci 19: 1.
13. Kong YC, Ng KH, Wat KH et al. 1985a. Yuehchukene, a novel anti-implantation indole alkaloid from Murraya paniculata. Planta Med 4: 304.
14. Kong YC, Chen KF, Cambie RC, Waterman PG. 1985b. Yuehchukene, a novel indole alkaloid with anti-implantation activity. Chem Commun 2: 47.
15. Machida K, Ueda J, Sato T, Osawa K, Andoh R, Hisamichi S. 1985. Constituents of Citrus hassaku hort ex. Tanaka. I. Structure and hypotensive effect of flavonoid glycosides in Citrus hassaku peelings. Annu Rep Tohoku Coll Pharm 32: 135.
16. Wafaa A., Aziza MM, Amer MM, Hassan AB, Soliman GA. 1990. Antimicrobial activity of Roemeria hybrida flavonoid glycoside. J Drug Res 19: 199.
17. Waterman PG. 1975. Alkalo ds of the Rutaceae: Their distribution and systematic significance. Biochem Syst Ecol 3: 149.