Occurrence of HCC in asymptomatic HCV-related chronic hepatitis

Digestive Diseases and Sciences

Volumn 47, Issue 11, 2002, Pages 2407-2410

  Persico, Marcello ^a   Palmentieri, Bruno ^a   Coppola, Leonardo ^a   Di Giacomo Russo, Giovanni ^a   De Marino, Fedele ^a   De Sio, Ilario ^a   Torella, Roberto ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Asymptomatic; HCC; HCV; Hepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE;

ADULT; ARTICLE; CANCER RISK; CARCINOGENESIS; CASE REPORT; CHRONIC HEPATITIS; DISEASE COURSE; HEPATITIS C VIRUS; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MALE; PRIORITY JOURNAL;

EID: 0036844692     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020527118782     Document Type: Article

References (18)

1. Colombo M, De Franchis R, Del Ninno F, Sangiovanni A, De Fazio C, Tommasini M, et al: Hepatocellular carcinoma in italian patients with cirrhosis. N Engl J Med 325:675-680, 1991
2. El-Refaie, Savage K, Bhattacharya S, Khakoo S, Harrison TJ, El-Batanony M, Soliman ES, Nasr S, Mokhtar N, Amer K, Scheuer PJ, Dhillon AP: HCV-associated hepatocellular carcinoma without cirrhosis. J Hepatol vol 24: 000, 1996
3. Grando-Lemaire V, Guettier C, Chevret S, Beaugrand M, Trinchet JC, Groupe d'étude et de traitement du carcinome hépatocellulaire: Hepatocellular carcinoma without cirrhosis in the West: Epidemiological factors and histopatology of the non-tumorous liver. J Hepatology 3:508-513, 1999
4. De Mitri MS, Poussin K, Pontisso P, D'errico A, Simon N, Grigioni W, Alberti A, Beaugrand M, Pisi E, Brèchot C, Paterlini P: HCV-associated liver cancer without cirrhosis. Lancet 345:413-415, 1995
5. Gerber MA: Relation of hepatitis C to hepatocellular carcinoma. J Hepatol 17(suppl 3):S108-S111, 1993
6. Caporaso N, Romano M, Marmo R, de Sio I, Morisco F, Minerva A, Coltorti M: Hepatitis C virus infection is an additive risk factor for development of hepatocellular carcinoma in patient with cirrhosis. J Hepatol 12:367-371, 1991
7. Alberti A, Chemelo L, Noventa F, Morsica G, Cavalletto D, Pontisso P, Roul A: Hepatitis C viremia and liver disease in symptom-free individuals with anti-HCV. Lancet 340:697, 1992
8. Shindo M, Ken A, Sokawa Y, Okuno T: The virological and histological state of anti-hepatitis C virus-positive subjects withnormal liver biochemical values. Hepatology 22:418-425, 1995
9. Sangiovanni A, Morales R, Spinzi GC, Rumi MG, Casiraghi A, Ceriani R, Colombo E, Fossati M, Prada M, Taviani E, Minoli G: Interferon alfa treatment of HCV RNA carriers with persistently normal aminotrasferase levels: A pilot randomized controlled study. Hepatology 26:853-856, 1998
10. Puoti C, Magrini A, Stati T, Rigato P, Montagnese F, Rossi P, Aldegheri L, Resta S: Clinical, histologic, and virological features of hepatitis C virus carriers with persistently normal or abnormal aminotrasferase levels. Hepatology 26:1393-1398, 1997
11. Trevisani F, D'Intino PE, Caraceni P, Pizzo M, Stefanini GF, Mazziotti A, Grazi GL, Gozzetti G, Gasbarrini G, Bernardi M: Etiologic factors and clinical presentation of hepatocellular carcinoma. Differences between cirrhotic and non cirrhotic Italian patients. Cancer May 75(9):2220-2232, 1995
12. Johnson PJ, Williams R: Cirrhosis and the etiology of hepatocellular carcinoma. J Hepatology 4:140-147, 1987
13. Di Bisceglie AM: Hepatitis C and hepatocellular carcinoma Semin Liver Dis. 15(1):64-69, 1995
14. Sakamoto D, Furukawa T, Takegami T: Hepatitis C virusnonstructural protein NS3 trasform NHI 3T3 cells. J Virol 69:3893-3896, 1995
15. Ray RB, Lagging LM, Meyer K, Steele R, Ray R: Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein. Virus Res 37:209-220, 1995
16. Kasahara N, Hayashi K, Mochizuki M, Takayanagi K, Yoshioka S, Kakumu A, Iijima A, Urushihara K, Kiyosowa M, Okuda K, Hino K, Okita, Osaka Liver disease Study Group: Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Hepatology 27:1394-1402, 1998
17. Popper H, Shafritz DA, Hoofnagle JH: Relation of hepatitis B virus carrier state to hepato-cellular carcinoma. Hepatology 7:764-772, 1987
18. Persico M, Persico E, Suozzo R, Conte S, De seta M, Coppola L, Palmentieri B, Sasso FC, Torella R: Natural history of hepatitis C virus carriers with persistently normal aminotrasferase levels. Gastroenterology 118:760-764, 2000