Karyomegalic nephropathy: An uncommon cause of progressive renal failure

Nephrology Dialysis Transplantation

Volumn 17, Issue 11, 2002, Pages 1914-1920

  Bhandari, Sunil ^a,f   Kalowski, Steven ^a   Collett, Paul ^a   Cooke, Bridget E ^c   Kerr, Peter ^d   Newland, Ronald ^b   Dowling, John ^e   Horvath, John ^a  

^a Statewide Renal Services   (Australia)

^b Department of Anatomical Pathology   (Canada)

^c PRINCE OF WALES HOSPITAL   (Australia)

^d ALFRED HOSPITAL   (Australia)

^e MONASH MEDICAL CENTRE   (Australia)

^f HULL ROYAL INFIRMARY   (United Kingdom)

Author keywords

Haematuria; Interstitial nephritis; Karyomegaly; Nephropathy; Ploidy; Proteinuria

Indexed keywords

CELL ANTIGEN; CYCLINE; CYCLOSPORIN; KI 67 ANTIGEN; LEUKOCYTE ANTIGEN; LIVER ENZYME; HLA ANTIGEN;

ADULT; ARTICLE; CAUSE OF DEATH; CLINICAL ARTICLE; CLINICAL FEATURE; DIAGNOSTIC PROCEDURE; DISEASE COURSE; EPITHELIUM CELL; FEMALE; GLOMERULONEPHRITIS; HEMATURIA; HEMOLYTIC UREMIC SYNDROME; HISTOLOGY; HUMAN; KARYOTYPING; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY EPITHELIUM; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; LUNG INFECTION; MALE; MITOSIS; PLOIDY; PRIORITY JOURNAL; PROTEINURIA; SCHOOL CHILD; SEPSIS; CASE REPORT; CHILD; CLASSIFICATION; ELECTRON MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MIDDLE AGED; PATHOPHYSIOLOGY; PEDIGREE;

ADULT; CHILD; DISEASE PROGRESSION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HLA ANTIGENS; HUMANS; KIDNEY DISEASES; KIDNEY FAILURE; MALE; MICROSCOPY, ELECTRON; MIDDLE AGED; PEDIGREE; PLOIDIES;

EID: 0036843122     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/17.11.1914     Document Type: Article

References (12)

1. Burry AF. Extreme dysplasia in renal epithelium of a young woman dying from hepatocarcinoma. J Pathol 1974; 113: 147-150
2. Mihatsch MJ, Gudat F, Zollinger HU et al. Systemic karyomegaly associated with chronic interstitial nephritis. A new disease entity. Clin Nephrol 1979; 12: 54-62
3. Sclare G. A case of unexplained karyomegaly. Beitr Pathol Bd 1976; 157: 301-306
4. Moch H, Spoendlin M, Schmassmann A, Mihatsch MJ. Systemic karyomegaly with chronic interstitial nephritis. Discussion of the disease picture based on an autopsy case. Pathologe 1994; 15: 44-48
5. Spoendlin M, Moch H, Brunner F et al. Karyomegalic interstitial nephritis: further support for a distinct entity and evidence for a genetic defect. Am J Kidney Dis 1995; 25: 242-252
6. Godin M, Francois A, Roy FL et al. Karyomegalic interstitial nephritis. Am J Kidney Dis 1996; 27: 166
7. Vadiaka M, Sotsiou F, Koufos C. A case of systemic karyomegaly associated with interstitial nephritis. Ann Med Interne (Paris) 1998; 149: 291-294
8. Shulte E. Haematoxylin and the Feulgen reagent in nuclear staining. In: Boon ME, Kok LP, eds. Standardization and Quantification of Diagnostic Staining in Cytology. Coulomb Press, Leyden, Netherlands, 1986: 15-26
9. Lockart RZ, Pezzella KM, Toy ST. Features independent of stain intensity for evaluation Feulgen-stained cells. Anal Quant Cytol Histol 1984; 6: 105-111
10. Weid GL, Bartels PH, Bibbo M, Dytch HE. Image analysis in quantitative cytopathology and histopathology. Hum Pathol 1984; 20: 549-571
11. Mantle PG, McHugh KM, Adatia R et al. Persistent karyomegaly caused by Penicillium nephrotoxins in the rat. Proc R Soc Lond B Biol Sci 1991; 246: 251-259
12. Fujimoto Y, Oyamada M, Hattori A et al. Accumulation of abnormality high ploid nuclei in the liver of LEC rats developing spontaneous hepatitis. Jpn J Cancer Res 1989; 80: 45-50