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Volumn 18, Issue 11, 2002, Pages 555-559

Genotype - Phenotype mapping: Genes as computer programs

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER PROGRAM; GENE CONVERSION; GENE INTERACTION; GENE MAPPING; GENE MUTATION; GENETIC RECOMBINATION; GENOTYPE; PHENOTYPE; PRIORITY JOURNAL; REVIEW;

EID: 0036842183     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(02)02765-8     Document Type: Review
Times cited : (63)

References (66)
  • 1
    • 0030071902 scopus 로고    scopus 로고
    • From DNA sequence to biological function
    • Oliver S.G. From DNA sequence to biological function. Nature. 379:1996;597-600.
    • (1996) Nature , vol.379 , pp. 597-600
    • Oliver, S.G.1
  • 2
    • 0032491377 scopus 로고    scopus 로고
    • Predicting function: From genes to genomes and back
    • Bork P., et al. Predicting function: From genes to genomes and back. J. Mol. Biol. 283:1998;707-725.
    • (1998) J. Mol. Biol. , vol.283 , pp. 707-725
    • Bork, P.1
  • 3
    • 0033528999 scopus 로고    scopus 로고
    • Functional genomics: Learning to think about gene expression data
    • Brent R. Functional genomics: Learning to think about gene expression data. Curr. Biol. 9:1999;R338-R341.
    • (1999) Curr. Biol. , vol.9
    • Brent, R.1
  • 4
    • 0034614598 scopus 로고    scopus 로고
    • Genomic biology
    • Brent R. Genomic biology. Cell. 100:2000;169-183.
    • (2000) Cell , vol.100 , pp. 169-183
    • Brent, R.1
  • 5
    • 0034948115 scopus 로고    scopus 로고
    • Genomic computing: Explanatory analysis of plant expression profiling data using machine learning
    • Kell D.B., et al. Genomic computing: explanatory analysis of plant expression profiling data using machine learning. Plant Physiol. 126:2001;943-951.
    • (2001) Plant Physiol. , vol.126 , pp. 943-951
    • Kell, D.B.1
  • 6
    • 0002459646 scopus 로고    scopus 로고
    • Snapshots of systems: Metabolic control analysis and biotechnology in the post-genomic era
    • Cornish-Bowden, A. and Cárdenas, M.L., eds. Kluwer Academic Publishers
    • Kell, D.B. and Mendes, P. (2000) Snapshots of systems: Metabolic control analysis and biotechnology in the post-genomic era. In Technological and Medical Implications of Metabolic Control Analysis (Cornish-Bowden, A. and Cárdenas, M.L., eds.), pp. 3-25 (and see http://qbab.aber.ac.uk/dbk/mca99.htm). Kluwer Academic Publishers.
    • (2000) Technological and Medical Implications of Metabolic Control Analysis , pp. 3-25
    • Kell, D.B.1    Mendes, P.2
  • 7
    • 0030921160 scopus 로고    scopus 로고
    • Biochemistry by numbers: Simulation of biochemical pathways with Gepasi 3
    • Mendes P. Biochemistry by numbers: simulation of biochemical pathways with Gepasi 3. Trends Biochem. Sci. 22:1997;361-363.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 361-363
    • Mendes, P.1
  • 8
    • 0033031386 scopus 로고    scopus 로고
    • E-CELL: Software environment for whole-cell simulation
    • Tomita M., et al. E-CELL: software environment for whole-cell simulation. Bioinformatics. 15:1999;72-84.
    • (1999) Bioinformatics , vol.15 , pp. 72-84
    • Tomita, M.1
  • 9
    • 0034119624 scopus 로고    scopus 로고
    • Mathematical modelling of metabolism
    • Giersch C. Mathematical modelling of metabolism. Curr. Opin. Plant Biol. 3:2000;249-253.
    • (2000) Curr. Opin. Plant Biol. , vol.3 , pp. 249-253
    • Giersch, C.1
  • 10
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • Edwards J.S., et al. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat. Biotechnol. 19:2001;125-130.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 125-130
    • Edwards, J.S.1
  • 11
    • 0034644270 scopus 로고    scopus 로고
    • The segment polarity network is a robust development module
    • von Dassow G., et al. The segment polarity network is a robust development module. Nature. 406:2000;188-192.
    • (2000) Nature , vol.406 , pp. 188-192
    • Von Dassow, G.1
  • 12
    • 0032406131 scopus 로고    scopus 로고
    • Non-linear optimization of biochemical pathways: Applications to metabolic engineering and parameter estimation
    • Mendes P., Kell D.B. Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation. Bioinformatics. 14:1998;869-883.
    • (1998) Bioinformatics , vol.14 , pp. 869-883
    • Mendes, P.1    Kell, D.B.2
  • 13
    • 0033736476 scopus 로고    scopus 로고
    • Genetic network inference: From co-expression clustering to reverse engineering
    • D'haeseleer P., et al. Genetic network inference: from co-expression clustering to reverse engineering. Bioinformatics. 16:2000;707-726.
    • (2000) Bioinformatics , vol.16 , pp. 707-726
    • D'haeseleer, P.1
  • 18
    • 0034160040 scopus 로고    scopus 로고
    • On the optimization of classes for the assignment of unidentified reading frames in functional genomics programmes: The need for machine learning
    • Kell D.B., King R.D. On the optimization of classes for the assignment of unidentified reading frames in functional genomics programmes: the need for machine learning. Trends Biotechnol. 18:2000;93-98.
    • (2000) Trends Biotechnol. , vol.18 , pp. 93-98
    • Kell, D.B.1    King, R.D.2
  • 19
    • 0032441150 scopus 로고    scopus 로고
    • Cluster analysis and display of genome-wide expression patterns
    • Eisen M.B., et al. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U. S. A. 95:1998;14863-14868.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 14863-14868
    • Eisen, M.B.1
  • 20
    • 0033027794 scopus 로고    scopus 로고
    • Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
    • Tamayo P., et al. Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation. Proc. Natl. Acad. Sci. U. S. A. 96:1999;2907-2912.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 2907-2912
    • Tamayo, P.1
  • 21
    • 0035367064 scopus 로고    scopus 로고
    • Whole-genome expression analysis: Challenges beyond clustering
    • Altman R.B., Raychaudhuri S. Whole-genome expression analysis: challenges beyond clustering. Curr. Opin. Struct. Biol. 11:2001;340-347.
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , pp. 340-347
    • Altman, R.B.1    Raychaudhuri, S.2
  • 26
    • 0034628487 scopus 로고    scopus 로고
    • Proteomics: Guilt-by-association goes global
    • Oliver S.G. Proteomics: guilt-by-association goes global. Nature. 403:2000;601-603.
    • (2000) Nature , vol.403 , pp. 601-603
    • Oliver, S.G.1
  • 27
    • 0033780652 scopus 로고    scopus 로고
    • Guilt by association
    • Altshuler D., et al. Guilt by association. Nat. Genet. 26:2000;135-137.
    • (2000) Nat. Genet. , vol.26 , pp. 135-137
    • Altshuler, D.1
  • 28
    • 1942422934 scopus 로고
    • Model uncertainty, data mining and statistical inference
    • Chatfield C. Model uncertainty, data mining and statistical inference. J. R. Stat. Soc. Ser. A. 158:1995;419-466.
    • (1995) J. R. Stat. Soc. Ser. A , vol.158 , pp. 419-466
    • Chatfield, C.1
  • 29
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer L.J., et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 415:2002;530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • Van't Veer, L.J.1
  • 30
    • 0037116832 scopus 로고    scopus 로고
    • Use of proteomic patterns in serum to identify ovarian cancer
    • Petricoin E.F., et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet. 359:2002;572-577.
    • (2002) Lancet , vol.359 , pp. 572-577
    • Petricoin, E.F.1
  • 32
    • 0031718876 scopus 로고    scopus 로고
    • Multi-locus nonparametric linkage analysis of complex trait loci with neural networks
    • Lucek P., et al. Multi-locus nonparametric linkage analysis of complex trait loci with neural networks. Hum. Hered. 48:1998;275-284.
    • (1998) Hum. Hered. , vol.48 , pp. 275-284
    • Lucek, P.1
  • 33
    • 0030044168 scopus 로고    scopus 로고
    • Structure-activity relationships derived by machine learning: The use of atoms and their bond connectivities to predict mutagenicity by inductive logic programming
    • King R.D., et al. Structure-activity relationships derived by machine learning: The use of atoms and their bond connectivities to predict mutagenicity by inductive logic programming. Proc. Natl. Acad. Sci. U. S. A. 93:1996;438-442.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 438-442
    • King, R.D.1
  • 36
    • 0003602231 scopus 로고    scopus 로고
    • T. et al. Bäck. IOP Publishing/Oxford University Press
    • Bäck T., et al. Handbook of Evolutionary Computation. 1997;IOP Publishing/Oxford University Press.
    • (1997) Handbook of Evolutionary Computation
  • 37
    • 0035375033 scopus 로고    scopus 로고
    • Evolutionary computation
    • Foster J.A. Evolutionary computation. Nat. Rev. Genet. 2:2001;428-436.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 428-436
    • Foster, J.A.1
  • 43
    • 0002159118 scopus 로고    scopus 로고
    • Defence against the flood: A solution to the data mining and predictive modelling challenges of today
    • Kell D.B. Defence against the flood: a solution to the data mining and predictive modelling challenges of today. Bioinformatics World. 1:2002;16-18.
    • (2002) Bioinformatics World , vol.1 , pp. 16-18
    • Kell, D.B.1
  • 44
    • 0002258659 scopus 로고
    • A representation for the adaptive generation of simple sequential programs
    • Cramer N.L. A representation for the adaptive generation of simple sequential programs. Int. Conf. Genetic Algorithms and their Applications. 1985;183-187.
    • (1985) Int. Conf. Genetic Algorithms and their Applications , pp. 183-187
    • Cramer, N.L.1
  • 47
    • 0033136116 scopus 로고    scopus 로고
    • Toward metabolic phenomics: Analysis of genomic data using flux balances
    • Schilling C.H., et al. Toward metabolic phenomics: Analysis of genomic data using flux balances. Biotechnol. Prog. 15:1999;288-295.
    • (1999) Biotechnol. Prog. , vol.15 , pp. 288-295
    • Schilling, C.H.1
  • 48
    • 0001457344 scopus 로고    scopus 로고
    • Explanatory analysis of the metabolome using genetic programming of simple, interpretable rules
    • Johnson H.E., et al. Explanatory analysis of the metabolome using genetic programming of simple, interpretable rules. Genetic Progr. Evolvable Machines. 1:2000;243-258.
    • (2000) Genetic Progr. Evolvable Machines , vol.1 , pp. 243-258
    • Johnson, H.E.1
  • 49
    • 0035160371 scopus 로고    scopus 로고
    • A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
    • Raamsdonk L.M., et al. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat. Biotechnol. 19:2001;45-50.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 45-50
    • Raamsdonk, L.M.1
  • 50
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics: The link between genotypes and phenotypes
    • Fiehn O. Metabolomics: the link between genotypes and phenotypes. Plant Mol. Biol. 48:2002;155-171.
    • (2002) Plant Mol. Biol. , vol.48 , pp. 155-171
    • Fiehn, O.1
  • 51
    • 0035007365 scopus 로고    scopus 로고
    • Dissecting the genetic pathway to extreme fruit size in tomato using a cross between the small-fruited wild species Lycopersicon pimpinellifolium and L. esculentum var. giant heirloom
    • Lippman Z., Tanksley S.D. Dissecting the genetic pathway to extreme fruit size in tomato using a cross between the small-fruited wild species Lycopersicon pimpinellifolium and L. esculentum var. giant heirloom. Genetics. 158:2001;413-422.
    • (2001) Genetics , vol.158 , pp. 413-422
    • Lippman, Z.1    Tanksley, S.D.2
  • 52
    • 0035400051 scopus 로고    scopus 로고
    • Genetical genomics: The added value from segregation
    • Jansen R.C., Nap J.P. Genetical genomics: the added value from segregation. Trends Genet. 17:2001;388-391.
    • (2001) Trends Genet. , vol.17 , pp. 388-391
    • Jansen, R.C.1    Nap, J.P.2
  • 53
    • 0036245218 scopus 로고    scopus 로고
    • Mapping and analysis of quantitative trait loci in experimental populations
    • Doerge R.W. Mapping and analysis of quantitative trait loci in experimental populations. Nat. Rev. Genet. 3:2002;43-52.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 43-52
    • Doerge, R.W.1
  • 55
    • 0032805974 scopus 로고    scopus 로고
    • Overview of QTL mapping software and introduction to Map Manager QT
    • Manly K.F., Olson J.M. Overview of QTL mapping software and introduction to Map Manager QT. Mamm. Genome. 10:1999;327-334.
    • (1999) Mamm. Genome , vol.10 , pp. 327-334
    • Manly, K.F.1    Olson, J.M.2
  • 56
    • 0035380102 scopus 로고    scopus 로고
    • Finding the molecular basis of quantitative traits: Successes and pitfalls
    • Flint J., Mott R. Finding the molecular basis of quantitative traits: Successes and pitfalls. Nat. Rev. Genet. 2:2001;437-445.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 437-445
    • Flint, J.1    Mott, R.2
  • 57
    • 0002191565 scopus 로고
    • Control analysis of microbial growth and productivity
    • Kell D.B., et al. Control analysis of microbial growth and productivity. Symp. Soc. Gen. Microbiol. 44:1989;61-93.
    • (1989) Symp. Soc. Gen. Microbiol. , vol.44 , pp. 61-93
    • Kell, D.B.1
  • 58
    • 84978711394 scopus 로고
    • Kinetics of multi-enzyme systems
    • H.J. et al. Rehm. Verlag Chemie
    • Cornish-Bowden A. Kinetics of multi-enzyme systems. Rehm H.J., et al. Biotechnology. 9:1995;121-136 Verlag Chemie.
    • (1995) Biotechnology , vol.9 , pp. 121-136
    • Cornish-Bowden, A.1
  • 59
    • 0030573816 scopus 로고    scopus 로고
    • What BioTechnologists knew all along?
    • Westerhoff H.V., Kell D.B. What BioTechnologists knew all along? J. Theor. Biol. 182:1996;411-420.
    • (1996) J. Theor. Biol. , vol.182 , pp. 411-420
    • Westerhoff, H.V.1    Kell, D.B.2
  • 61
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub T.R., et al. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science. 286:1999;531-537.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1
  • 62
    • 0036210918 scopus 로고    scopus 로고
    • Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer
    • Jones M.B., et al. Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer. Proteomics. 2:2002;76-84.
    • (2002) Proteomics , vol.2 , pp. 76-84
    • Jones, M.B.1
  • 63
    • 0032524383 scopus 로고    scopus 로고
    • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome
    • Wang D.G., et al. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science. 280:1998;1077-1082.
    • (1998) Science , vol.280 , pp. 1077-1082
    • Wang, D.G.1
  • 64
    • 0035919656 scopus 로고    scopus 로고
    • Haplotype variation and linkage disequilibrium in 313 human genes
    • Stephens J.C., et al. Haplotype variation and linkage disequilibrium in 313 human genes. Science. 293:2001;489-493.
    • (2001) Science , vol.293 , pp. 489-493
    • Stephens, J.C.1
  • 65
    • 0034930262 scopus 로고    scopus 로고
    • The relative power of SNPs and haplotype as genetic markers for association tests
    • Bader J.S. The relative power of SNPs and haplotype as genetic markers for association tests. Pharmacogenomics. 2:2001;11-24.
    • (2001) Pharmacogenomics , vol.2 , pp. 11-24
    • Bader, J.S.1
  • 66
    • 0033967014 scopus 로고    scopus 로고
    • Microarray technology - Enhanced versatility, persistent challenge
    • Epstein C.B., Butow R.A. Microarray technology - Enhanced versatility, persistent challenge. Curr. Opin. Biotechnol. 11:2000;36-41.
    • (2000) Curr. Opin. Biotechnol. , vol.11 , pp. 36-41
    • Epstein, C.B.1    Butow, R.A.2


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