Platelet collagen receptor GPIa (C807T/HPA-5) haplotype is not associated with an increased risk of fatal coronary events in middle-aged men

Atherosclerosis

Volumn 165, Issue 1, 2002, Pages 111-118

  Mikkelsson, Jussi ^a   Perola, Markus ^d,e   Penttilä, Antti ^b   Karhunen, Pekka J ^a,c  

^a UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Coronary thrombosis; Genetics; Glycoprotein GPIa IIa; Myocardial infarction; Polymorphism

Indexed keywords

PLATELET COLLAGEN RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ADULT; AGED; ALLELE; ARTICLE; AUTOPSY; CAUCASIAN; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY THROMBOSIS; DISEASE ASSOCIATION; DNA POLYMORPHISM; FATALITY; FINLAND; GENE EXPRESSION; GENOTYPE; HAPLOTYPE; HEART DEATH; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RISK FACTOR; SUDDEN DEATH; SURFACE PROPERTY; THROMBOCYTE ADHESION; THROMBOGENESIS;

AGE FACTORS; ANALYSIS OF VARIANCE; AUTOPSY; CORONARY THROMBOSIS; DEATH, SUDDEN, CARDIAC; FINLAND; GENE EXPRESSION REGULATION; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; POLYMORPHISM, GENETIC; PROBABILITY; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SAMPLING STUDIES;

EID: 0036841888     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(02)00110-7     Document Type: Article

References (51)

1. Salomaa V.V., Lundberg V., Agnarsson U., Radisauskas R., Kirchhoff M., Wilhelmsen L. Fatalities from myocardial infarction in Nordic countries and Lithuania. The MONICA Investigators. Eur. Heart J. 18:1997;91-98.
2. Mehta D., Curwin J., Gomes A., Fuster V. Sudden death in coronary artery disease. Acute ischemia versus myocardial substrate. Circulation. 96:1997;3215-3223.
3. Traven N.D., Kuller L.H., Ives D.G., Rutan G.H., Perper J.A. Coronary heart disease mortality and sudden death among the 35-44-year age group in Allegheny County, Pennsylvania. Ann. Epidemiol. 6:1996;130-136.
4. Kannel W.B., Schatzkin A. Sudden death: lessons from subsets in population studies. J. Am. Coll. Cardiol. 5:(6 Suppl.):1985;141B-149B.
5. Gillum R.F. Sudden coronary death in the United States:1980-85. Circulation. 79:1989;756-765.
6. Escobedo L.G., Caspersen C.J. Risk factors for sudden coronary death in the United States. Epidemiology. 8:1997;175-180.
7. Sexton P.T., Walsh J., Jamrozik K., Parsons R. Risk factors for sudden unexpected cardiac death in Tasmanian men. Aust. N.Z. J. Med. 27:1997;45-50.
8. Escobedo L.G., Zack M.M. Comparison of sudden and nonsudden coronary deaths in the United States. Circulation. 93:1996;2033-2036.
9. Wannamethee G., Shaper A.G., Macfarlane P.W., Walker M. Risk factors for sudden cardiac death in middle-aged British men. Circulation. 91:1995;1749-1756.
10. Jouven X., Desnos M., Guerot C., Ducimetiere P. Predicting sudden death in the population. Circulation. 99:1999;1978-1983.
11. Friedlander Y., Siscovick D.S., Weinmann S., et al. Family history as a risk factor for primary cardiac arrest. Circulation. 97:1998;155-160.
12. Chesebro J.H., Fuster V. Thrombosis in unstable angina. N. Engl. J. Med. 327:1992;192-194.
13. Badimon L., Chesebro J.H., Badimon J.J. Thrombus formation on ruptured atherosclerotic plaques and rethrombosis on evolving thrombi. Circulation. 86:1992;III74-III85.
14. Burke A.P., Farb A., Malcom G.T., Liang Y., Smialek J., Virmani R. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N. Engl. J. Med. 336:1997;1276-1282.
15. Badimon J.J., Fuster V., Chesebro J.H., Badimon L. Coronary atherosclerosis: a multifactorial disease. Circulation. 87:1993;II3-II16.
16. Leach I.H., Blundell J.W., Rowley J.M., Turner D.R. Acute ischaemic lesions in death due to ischaemic heart disease. An autopsy study of 333 cases of out-of-hospital death. Eur. Heart J. 16:1995;1181-1185.
17. Mikkelsson J., Perola M., Penttila A., Karhunen P.J. Platelet GP Ibα HPA-2 Met/VNTR B haplotype as a genetic predictor of myocardial infarction and sudden cardiac death. Circulation. 104:2001;876-880.
18. Mailhac A., Badimon J.J., Fallon J.T., et al. Effect of an eccentric severe stenosis on fibrin(ogen) deposition on severely damaged vessel wall in arterial thrombosis. Relative contribution of fibrin(ogen) and platelets. Circulation. 90:1994;988-996.
19. Freifeld A.G., Schuster E.H., Bulkley B.H. Nontransmural versus transmural myocardial infarction. A morphologic study. Am. J. Med. 75:1983;423-432.
20. Kragel A.H., Gertz D., Roberts W.C. Morphologic comparison of frequency and types of acute lesions in the major epicardial coronary arteries in unstable angina pectoris, sudden coronary death and acute myocardial infarction. J. Am. College Cardiol. 18:1991;801-808.
21. Keen W.D., Savage M.P., Fischman D.L., Zalewski A., Walinsky P., Nardone D., Goldberg S. Comparison of coronary angiographic findings during the first six hours of non-Q-wave and Q-wave myocardial infarction. Am. J. Cardiol. 74:1994;324-328.
22. DeWood M.A., Spores J., Notske R., Mouser L.T., Burroughs R., Golden M.S., Lang H.T. Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction. N. Engl. J. Med. 303:1980;897-902.
23. Schwartz C.J., Gerrity R.G. Anatomical pathology of sudden unexpected cardiac death. Circulation. 51-52:(Suppl. III):1975;18-26.
24. Stehbens W.E. Relationship of coronary-artery thrombosis to myocardial infarction. Lancet. 8456:1985;639-642.
25. Rosenfeld S.J., Gralnick H.R. Adhesive interactions in hemostasis. Acta Haematol. 97:1997;118-125.
26. Ruggeri Z.M., Dent J.A., Saldivar E. Contribution of distinct adhesive interactions to platelet aggregation in flowing blood. Blood. 94:1999;172-178.
27. Savage B., Saldivar E., Ruggeri Z.M. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand Factor. Cell. 84:1996;289-297.
28. Fuster V., Badimon J.J., Badimon L., Chesebro J.H. The pathogenesis of coronary artery disease and the acute coronary syndromes (Part II). N. Engl. J. Med. 326:1992;310-317.
29. Reiner A.P., Aramaki K.M., Teramura G., Gaur L. Analysis of platelet glycoprotein Ia (alpha2 integrin) allele frequencies in three North American populations reveals genetic association between nucleotide 807C/T and amino acid 505 Glu/Lys (HPA-5) dimorphisms. Thromb. Haemostasis. 80:1998;449-456.
30. Corral J., Rivera J., Gonzalez-Conejero R., Vicente V. The number of platelet glycoprotein Ia molecules is associated with the genetically linked 807 C/T and HPA-5 polymorphisms. Transfusion. 39:1999;372-378.
31. Kritzik M., Savage B., Nugent D.J., Santoso S., Ruggeri Z.M., Kunicki T.J. Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2beta1 density. Blood. 92:1998;2382-2388.
32. Kunicki T.J., Orchekowski R., Annis D., Honda Y. Variability of integrin alpha 2 beta 1 activity on human platelets. Blood. 82:1993;2693-2703.
33. Santoro S.A. Platelet surface collagen receptor polymorphisms: variable receptor expression and thrombotic/hemorrhagic risk. Blood. 93:1999;3575-3577.
34. Corral J., Gonzalez-Conejero R., Rivera J., Ortuno F., Aparicio P., Vicente V. Role of the 807 C/T polymorphism of the alpha2 gene in platelet GP Ia collagen receptor expression and function. Thromb. Haemostasis. 81:1999;951-956.
35. Jacquelin B., Tarantino M.D., Kritzik M., Rozenshteyn D., Koziol J.A., Nurden A.T., Kunicki T.J. Allele-dependent transcriptional regulation of the human integrin alpha(2) gene. Blood. 97:2001;1721-1726.
36. Moshfegh K., Wuillemin W.A., Redondo M., Lämmle B., Beer J.H., Liechti-Gallati S., Meyer B.J. Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: a case-control study. Lancet. 353:1998;351-354.
37. Santoso S., Kunicki T.J., Kroll H., Haberbosch W., Gardemann A. Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients. Blood. 93:1999;2449-2453.
38. Croft S.A., Hampton K.K., Sorrell J.A., Steeds R.P., Channer K.S., Samani N.J., Daly M.E. The GPIa C807T dimorphism associated with platelet collagen receptor density is not a risk factor for myocardial infarction. Br. J. Haematol. 106:1999;771-776.
39. Kroll H., Gardemann A., Fechter A., Haberbosch W., Santoso S. The impact of the glycoprotein Ia collagen receptor subunit A1648G gene polymorphism on coronary artery disease and acute myocardial infarction. Thromb. Haemostasis. 83:2000;392-396.
40. Morita H., Kurihara H., Imai Y., Sugiyama T., Hamada C., Sakai E., Mori M., Nagai R. Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and myocardial infarction in Japanese. Thromb. Haemostasis. 85:2001;226-230.
41. Casorelli I., De Stefano V., Leone A.M., et al. The C807T/G873A polymorphism in the platelet glycoprotein Ia gene and the risk of acute coronary syndrome in the Italian population. Br. J. Haematol. 114:2001;150-154.
42. Kekomaki S., Partanen J., Kekomaki R. Platelet alloantigens HPA-1, -2, -3, -5 and -6 in Finns. Transfusion Med. 5:1995;193-198.
43. A polymorphism and the development of early elevated coronary lesions. Atherosclerosis. 154:2001;721-727.
44. 1 is associated with increased risk of cardiovascular mortality in high-risk women. Circulation. 102:2000;1645-1650.
45. Anvari A., Janisiw M., Turel Z., Huber K., Fischer G., Panzer S. Platelet glycoprotein Ia gene dimorphism alpha2-807 in malignant arrhythmia in coronary artery disease. Thromb. Res. 98:2000;281-286.
46. A1/A2 polymorphism and sudden cardiac death. J. Am. Coll. Cardiol. 36:2000;1317-1323.
47. Carlsson L.E., Greinacher A., Spitzer C., Walther R., Kessler C. Polymorphisms of the human platelet antigens HPA-1, HPA-2, HPA-3 and HPA-5 on the platelet receptors for fibrinogen (GPIIb/IIIa), von Willebrand factor (GPIb/IX), and collagen (GPIa/IIa) are not correlated with an increased risk of stroke. Stroke. 28:1997;1392-1395.
48. Sperr W.R., Huber K., Roden M., et al. Inherited platelet glycoprotein polymorphisms and a risk for coronary heart disease in young central Europeans. Thromb. Res. 90:1998;117-123.
49. Carlsson L.E., Santoso S., Spitzer C., Kessler C., Greinacher A. The alpha2 gene coding sequence T807/A873 of the platelet collagen receptor integrin alpha2beta1 might be a genetic risk factor for the development of stroke in younger patients. Blood. 93:1999;3583-3586.
50. Von Beckerath N., Koch W., Mehilli J., Bottiger C., Schomig A., Kastrati A. Glycoprotein Ia gene C807T polymorphism and risk for major adverse cardiac events within the first 30 days after coronary artery stenting. Blood. 95:2000;3297-3301.
51. Von Beckerath N., Koch W., Mehilli J., Bottiger C., Braun S., Schomig A., Kastrati A. Glycoprotein Ia C807T polymorphism and risk of restenosis following coronary stenting. Atherosclerosis. 156:2001;463-468.