Impairment of male fertility induced by muscarinic receptor antagonists in rats

Reproductive Toxicology

Volumn 16, Issue 6, 2002, Pages 757-765

  Ban, Yoshiki ^a   Sato, Takahiro ^a   Nakatsuka, Toshio ^a   Kemi, Masayuki ^a   Samura, Keiji ^a   Matsumoto, Hiroyoshi ^a   Cukierski, Mark A ^b   Van Zwieten, Matthew J ^b  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Fertility; Male; Muscarinic receptor antagonist; Rat

Indexed keywords

ATROPINE; COMPOUND A; MUSCARINIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; FEMALE; FERTILITY; GESTATIONAL AGE; HISTOPATHOLOGY; MALE; MALE INFERTILITY; MATING; NIDATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PREGNANCY; PREGNANCY RATE; RAT; RAT STRAIN; REPRODUCTION; SPERMATOGENESIS; SPERMATOZOON MOTILITY; TESTIS;

ADMINISTRATION, ORAL; ANIMALS; ATROPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; FERTILITY; MALE; MUSCARINIC ANTAGONISTS; PREGNANCY; PREGNANCY RATE; RATS; RATS, INBRED STRAINS; RECOVERY OF FUNCTION; SPERMATOGENESIS;

EID: 0036840393     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(02)00050-3     Document Type: Article

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