Acylcarnitine profiles of preterm infants over the first four weeks of life

Pediatric Research

Volumn 52, Issue 5, 2002, Pages 720-723

  Meyburg, Jochen ^a   Schulze, Andreas ^a   Kohlmueller, Dirk ^a   Pöschl, Johannes ^a   Linderkamp, Otwin ^a   Hoffmann, Georg F ^a   Mayatepek, Ertan ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; CARNITINE;

ARTICLE; BLOOD SAMPLING; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; INBORN ERROR OF METABOLISM; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; NEWBORN; PERINATAL PERIOD; PREMATURITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; RISK FACTOR;

EID: 0036840197     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200211000-00018     Document Type: Article

References (26)

1. Chace DH, Hillman SL, van Hove JL, Naylor EW 1997 Rapid diagnosis of MCAD deficiency: Quantitatively analysis of octanoylcarnitine and other acylcarnitines in newborn blood spots by tandem mass spectrometry. Clin Chem 43:2106-2113
2. Rashed MS, Ozand PT, Bucknall MP, Little D 1995 Diagnosis of inborn errors of metabolism from blood spots by acylcarnitines and amino acids profiling using automated electrospray tandem mass spectrometry. Pediatr Res 38:324-331
3. Schulze A, Kohlmüller D, Mayatepek E 1999 Sensitivity of electrospray-tandem mass spectro-metry using the phenylalanine/tyrosine-ratio for differential diagnosis of hyperphenylalaninemia in neonates. Clin Chim Acta 283:15-20
4. Meyburg J, Schulze A, Kohlmüller D, Linderkamp O, Mayatepek E 2001 Postnatal changes in neonatal acylcarnitine profile. Pediatr Res 49:125-129
5. Shenai JP, Borum PR, Mohan P, Donlevy SC 1983 Carnitine status at birth of newborn infants of varying gestation. Pediatr Res 17:579-582
6. Schiff D, Chan G, Seccombe D, Hahn P 1979 Plasma carnitine levels during intravenous feeding of the neonate. J Pediatr 95:1043-1046
7. Bonner CM, DeBrie KL, Hug G, Landrigan E, Taylor BJ 1995 Effects of parenteral L-carnitine supplementation on fat metabolism and nutrition in premature neonates. J Pediatr 126:287-292
8. Arbeitsgemeinschaft für Pädiatrische Stoffwechselstörungen (APS) der Deutschen Gesellschaft für Kinderheilkunde 1997 Richtlinien zur Organisation und Durchführung des Neugeborenen-Screenings auf angeborene Stoffwechselstörungen und Endokrinopathien in Deutschland. Der Frauenarzt 38:1180-1184
9. Cederblad G, Svenningsen N 1986 Plasma carnitine and breast milk carnitine intake in premature infants. J Pediatr Gastroenterol Nutr 5:616-621
10. Mares-Perlman JA, Farrell PM, Gutcher GR 1986 Changes in erythrocyte and plasma carnitine concentrations in preterm neonates. Am J Clin Nutr 43:77-84
11. Melegh B, Szücs L, Kemer J, Sandor A 1988 Changes of plasma free amino acids and renal clearances of carnitines in premature infants during L-carnitine-supplemented human milk feeding. J Pediatr Gastroenterol Nutr 7:424-429
12. Melegh B, Kerner J, Sandor A, Vinceller M, Kispal G 1987 Effects of oral L-carnitine supplementation in low-birth-weight premature infants maintained on human milk. Biol Neonate 51:185-193
13. Schmidt-Sommerfeld E, Penn D, Wolf H 1982 Carnitine blood concentrations and fat utilization in parenterally alimented premature newborn infants. J Pediatr 100:260-264
14. Yeh YY, Cooke RJ, Zee P 1985 Impairment of lipid emulsion metabolism associated with carnitine insufficiency in premature infants. J Pediatr Gastroenterol Nutr 4:795-798
15. Shortland GJ, Walter JH, Stroud C, Fleming PJ, Speidel BD, Marlow N 1998 Randomised controlled trial of L-carnitine as a nutritional supplement in preterm infants. Arch Dis Child Fetal Neonatal Ed 78:F185-F188
16. Schmidt-Sommerfeld E, Penn D, Wolf H 1983 Carnitine deficiency in premature infants receiving total parenteral nutrition: Effect of L-carnitine supplementation. J Pediatr 102:931-935
17. Penn D, Schmidt-Sommerfeld E, Wolf H 1980 Carnitine deficiency in premature infants receiving total parenteral nutrition. Early Hum Dev 4:23-34
18. Fishlock RC, Bieber LL, Snoswell AM 1984 Sources of error in determinations of carnitine and acylcarnitine in plasma. Clin Chem 30:316-318
19. Shenai JP, Borum PR 1984 Tissue carnitine reserves of newborn infants. Pediatr Res 18:679-682
20. Penn D, Ludwigs B, Schmidt SE, Pascu F 1985 Effect of nutrition on tissue carnitine concentrations in infants of different gestational ages. Biol Neonate 47:130-135
21. Penn D, Schmidt-Sommerfeld E, Pascu F 1981 Decreased tissue carnitine concentrations in newborn infants receiving total parenteral nutrition. J Pediatr 98:976-978
22. Novak M, Monkus EF, Chung D, Buch M 1981 Carnitine in the perinatal metabolism of lipids. I. Relationship between maternal and fetal plasma levels of carnitine and acylcarnitines. Pediatrics 67:95-100
23. Cederblad G, Niklasson A, Rydgren B, Albertsson-Wikland K, Olegard R 1985 Carnitine in maternal and neonatal plasma. Acta Paediatr Scand 74:500-504
24. Schmidt-Sommerfeld E, Penn D, Sodha RJ, Prögler M, Novak M, Schneider H 1985 Transfer and metabolism of carnitine and carnitine esters in the in vitro perfused human placenta. Pediatr Res 19:700-706
25. Bernardini I, Evans MI, Nicolaides KH, Economides DL, Gahl WA 1991 The fetal concentrating index as a gestational age-independent measure of placental dysfuncfion in intrauterine growth retardation. Am J Obstet Gynecol 164:1481-1487
26. Campoy C, Bayes R, Peinado JM, Rivero M, Lopez C, Molina-Font JA 1998 Evaluation of carnitine nutritional status in fullterm newborn infants. Early Human Dev 53(Suppl):S149-S164