Proper usage of pancreatic enzymes

Current Opinion in Pulmonary Medicine

Volumn 8, Issue 6, 2002, Pages 542-546

  Schibli, Susanne ^a   Durie, Peter R ^a   Tullis, Elizabeth D ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PANCREAS ENZYME; PROTON PUMP INHIBITOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRIACYLGLYCEROL LIPASE;

COLON DISEASE; CYANOCOBALAMIN DEFICIENCY; CYSTIC FIBROSIS; DOSE RESPONSE; DRUG EFFICACY; DRUG OVERDOSE; ENTERIC COATED TABLET; ENTERIC FEEDING; ENZYME REPLACEMENT; FIBROSIS; HUMAN; LUNG FUNCTION; MALNUTRITION; MEDICAL LITERATURE; NUTRITIONAL STATUS; PANCREAS EXOCRINE INSUFFICIENCY; PANCREAS FUNCTION TEST; PATHOGENESIS; REVIEW;

COLONIC DISEASES; CYSTIC FIBROSIS; DRUG ADMINISTRATION SCHEDULE; HUMANS; PANCREATIN; PRACTICE GUIDELINES; RISK FACTORS; TREATMENT OUTCOME;

EID: 0036839363     PISSN: 10705287     EISSN: None     Source Type: Journal    
DOI: 10.1097/00063198-200211000-00010     Document Type: Review

References (15)

1. Van den Neucker AM, Kerkvliet EN, Theunissen PMVM, et al.: Acid steatocrit: A reliable screening tool for steatorrhea, Acta Paediatr 2001, 90:873-875.
2. Carroccio A, Verghi F, Santini B, et al.: Diagnostic accuracy of fecal elastase 1 assay in patlents with pancreatic maldigestion or intestinal malabsorption. Dig Dis Scien 2001, 46:1335-1342.
3. Koletzko S, Reinhardt D: Nutritional challenges of infants with cystic fibrosis. Early Hum Dev 2001, 65:S53-S61.
4. Soleimani M: Impaired pancreatic ductal bicarbonate secretion in cystic fibrosis. JOP. J. Pancreas (online) 2001:2 (4Suppl): 237-242.
5. Choi JY, Muallem D, Kiselyov K, et al.: Aberrant CFTR-dependent bicarbonate transport in mutations associated with cystic fibrosis. Nature 2001, 410:94-97.
6. De Lisle RC, Isom KS, Ziemer D, et al.: Changes in the exocrine pancreas secondary to altered small intestinal function in the CF mouse. Am J Physiol Gastrointest Liver Physiol 2001, 281:G 899-G 906. Increased acidity and significant increases in CF intestinal mRNA levels for secretin and vasoactive intestinal peptide were measured, suggesting that the CF pancreas may be chronically stimulated by hormonal signals, which, in turn, may lead to further plugging and progressive damage to the pancreas.
7. Hendriks JJE, Kester ADM, Doncherwolcke R, et al.: Changes in pulmonary hyperinflation and bronchial hyperresponsiveness following treatment with lansoprazole in children with cystic fibrosis. Pediatr Pulm 2001, 31:59-66.
8. Ter Heide H, Hendriks HJE, Heijmans H, et al.: Are children with cystic fibrosis who are treated with a proton-pump inhibitor at risk for vitamin B12 deficiency? J Pediatr Gastroenterol Nutr 2001, 33:342-345.
9. Butt AM, Ip W, Ellis L, et al.: The fate of ingested enzymes in cystic fibrosis. Pediatr Pulm 2001, 22(suppl):137-138. Preliminary data of intubation studies in three patients with CF suggest that delayed release of exogenous pancreatic enzymes in CF and a mismatch between the intestinal delivery of enzymes, bile acids, and ingested nutrients may contribute to the impaired intraluminal digestion of lipids in patients with PI caused by CF.
10. Walters S: Sex differences in weight perception and nutritional behavior in adults with cystic fibrosis. J Hum Nutr Diet 2001, 14:83-91. Individual weight perception seems to be a strong predictor of adherence to nutritional treatments and pancreatic enzyme replacement treatment. Young women with CF tend to overestimate their weight, and young men tend to underestimate it when compared with their actual body weight.
11. Mahta A. Further comments on fibrosing colonopathy study. Lancet 2001, 358:1546-1547. Audit of initial validated returns in patients attending CF centers in the United Kingdom (1999-2000) revealed that patients receiving standards-strength as well as high-strength pancreatic enzyme formulations commonly exceeded the current guidelines.
12. Bakowski M, Prescott P: Epidemiology of fibrosing colonopathy: US versus UK 1991-2001. European Cystic Fibrosis Conference 2002, abstract P 288.
13. Stevens JC, Davis M, Pawel BR, et al.: Fibrosing Colonopathy (FC): Retrospective analysis of U.S. cases 1995-1999. Pediatr Pulm 2001, abstract 501.
14. Conway SP, Morton A, Wolfe S: Enteral tube feeding for cystic fibrosis (Cochrane Review) In: The Cochrane Library, Issue 1, 2002. Oxford: update software.
15. Rozel JM, van Lieshout RH, Dankert-Roelse JE, et al.: Pancreatic enzyme supplementation in enteral tube feeding in children with cystic fibrosis. European Cystic Fibrosis Conference 2002. Abstract P 240.