Arachidonic acid signaling to the cytoskeleton: The role of cyclooxygenase and cyclic AMP-dependent protein kinase in actin bundling

Cell Motility and the Cytoskeleton

Volumn 53, Issue 3, 2002, Pages 239-250

  Glenn, Honor L ^a   Jacobson, Bruce S ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Actin organization; Adhesion; HeLa; Lipid second messengers; Prostaglandin E2

Indexed keywords

ACTIN; ARACHIDONIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; INTEGRIN; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE C;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL TRANSFORMATION; CELL VIABILITY; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; METABOLISM; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SECOND MESSENGER; SIGNAL TRANSDUCTION;

3T3 CELLS; ACTINS; ANIMALS; ARACHIDONIC ACIDS; CELL ADHESION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE INHIBITORS; CYTOSKELETON; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FIBROBLASTS; FORSKOLIN; HELA CELLS; HUMANS; MICE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SIGNAL TRANSDUCTION; STRESS FIBERS; TETRADECANOYLPHORBOL ACETATE;

EID: 0036838207     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/cm.10072     Document Type: Article

References (32)

1. Abedi H, Zachary I. 1997. Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells. J Biol Chem 272:15442-15451.
2. Busca R, Bertolotto C, Abbe P, Englaro W, Ishizaki T, Narumiya S, Boquet P, Ortonne J-P, Ballotti R. 1998. Inhibition of rho is required for cAMP-induced melanoma cell differentiation. Mol Biol Cell 9:1367-1378.
3. Chrzanowska-Wodnicka M, Burridge K. 1994. Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation. J Cell Sci 07:3643-3654.
4. Chrzanowska-Wodnicka M, Burridge K. 1996. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 133:1403-1415.
5. Chun J-S, Jacobson BS. 1992. Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clustering. Mol Biol Cell 3:481-492.
6. Chun J-S, Ha MJ, Jacobson BS. 1996. Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratum. J Biol Chem 271:13008-130012.
7. Chun J-S, Auer KA, Jacobson BS, 1997. Arachidonate initiated protein kinase C activation regulates HeLa cell spreading on a gelatin substrate by inducing f-actin formation and exocytotic upregulation of β1 integrin. J Cell Physiol 173:361-370.
8. Gilman AG. 1989. G proteins and regulation of adenylyl cyclase. JAMA 262:1819-1825.
9. Goeckeler ZM, Wysolmerski RB. 1995. Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation. J Cell Biol 130:613-627.
10. Gumbiner BM. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84:345-357.
11. Han J-D, Rubin CS. 1996. Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. J Biol Chem 271:29211-29215.
12. Harris DN, Asaad MM, Phillips MB, Goldenberg HJ, Antonaccio MJ. 1979. Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives. J Cyclic Nucleotide Res 5:125-134.
13. Johnson RA, Salomon Y. 1991. Assay of adenylyl cyclase catalytic activity. Methods Enzymol 195:3-21.
14. Juliano RL. 1987. Membrane receptors for extracellular matrix macromolecules: relationship to cell adhesion and tumor metastasis. Biochim Biophys Acta 907:261-278.
15. Kaibuchi K, Kuroda S, Amano M. 1999. Regulation of the cytoskeleton and cell adhesion by the rho family GPMAses in mammalian cells. Annu Rev Biochem 68:459-486.
16. Krebs EG. 1989. Role of the cyclic AMP-dependent protein kinase in signal transduction. JAMA 262:1815-1818.
17. Lamb NJC, Fernandez A, Coti MA, Adelstein R, Glass DB, Welch WJ, Feramisco JR. 1988. Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. J Cell Biol 106:1955-1971.
18. Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J. 1996. Protein kinase A phosphorylation of rhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO 15:510-519.
19. Lauffenburger DA, Horwitz AF. 1996. Cell migration: a physically integrated molecular process. Cell 84:359-369.
20. Lozano Y, Taitz A, Petruzzelli GJ, Djordjevic A, Young M. 1996. Prostaglandin E2-protein kinase A signaling and protein phosphatases-1 and -2A regulate human head and neck squamous cell carcinoma motility, adherence, and cytoskeletal organization. Prostaglandins 51:35-48.
21. McNamee CJ, Pennington SR, Sheterline P. 1995. Cell cycle-dependent morphological changes in the actin cytoskeleton induced by agents which elevate cyclic AMP. Cell Biol Int 19:769-775.
22. O'Connor KL, Nguyen B-K, Mercurio AM. 2000. RhoA function in lamellae formation and migration is regulated by the α6β4 integrin and cAMP metabolism. J Cell Biol 148:253-258.
23. Padmanabhan J, Clayton D, Shelanski ML. 1999. Dibutyryl cyclic AMP-induced process formation in astrocytes is associated with a decrease in tyrosine phosphorylation of focal adhesion kinase and paxillin. J Neurobiol 29:407-422.
24. Pokorna E, Jordan PW, O'Neill CH, Zicha D, Gilbert CS, Vesely P. 1994. Actin cytoskeleton and motility in rat sarcoma cell populations with different metastatic potential. Cell Motil Cytoskeleton 28:25-33.
25. Ridley AJ, Hall A. 1992. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70:389-399.
26. Roberts L, Glenn HL, Whitfield RA, Jacobson BS. 2001. Regulation of cell-substrate adhesion by the lipoxygenase and cyclooxygenase branches of arachidonic acid metabolism. In: Honn K, editor. Eicosanoids and other bioactive lipids in cancer, inflammation, and radiation injury, vol 5. New York: Kluwer Academic/Plenum Publishers.
27. Roger PP, Rickaert F, Huez G, Authelet M, Hofmann F, Dumont JE. 1988. Microinjection of catalytic subunit of cyclic AMP-dependent protein kinases triggers acute morphological changes in thyroid epithelial cells. FEBS Lett 232:409-413.
28. Skuta G, Ho C-H, Grinnell F. 1999. Increased myosin light chain phosphorylation is not required for growth factor stimulation of collagen matrix contraction. J Biol Chem 274:30163-30168.
29. Smith WL, Garavito RM, DeWitt DL. 1996. Prostaglandin endoperoxide H synthase (cyclooxygenases)-1 and -2. J Biol Chem 271:33157-33160.
30. Stockton RA, Jacobson BS. 2001. Modulation of cell-substrate adhesion by arachidonic acid: lipoxygenase regulates cell spreading and erk1/2-inducible cyclooxygenase regulates cell migration in NIH-3T3 fibroblasts. Mol Biol Cell 12:1937-1956.
31. Verin AD, Gilbert-McClain LI, Patterson CE, Garcia JGN. 1998. Biochemical regulation of the nonmuscle myosin light chain kinase isoform in bovine endothelium. Am J Respir Cell Mol Biol 19:767-776.
32. 2-mediated arachidonic acid release required for NIH-3T3 cell spreading. Biochem Biophys Res Commun 258:306-312.