Study of second-site suppression in the pheP gene for the phenylalanine transporter of Escherichia coli

Journal of Bacteriology

Volumn 184, Issue 21, 2002, Pages 5842-5847

  Pi, Jing ^a   Chow, H ^a   Pittard, A J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; PHENYLALANINE TRANSPORTER; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENE; ESCHERICHIA COLI; GENE REPRESSION; NONHUMAN; PHEP GENE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; BACTERIAL PROTEINS; CONSENSUS SEQUENCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GENES, BACTERIAL; GLUTAMIC ACID; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; ORGANIC ANION TRANSPORTERS; PHENYLALANINE; PROLINE; TYROSINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0036838011     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.21.5842-5847.2002     Document Type: Article

References (15)

1. Cosgriff, A., G. Brasier, J. Pi, C. Dogovski, J. P. Sarsero, and A. J. Pittard. 2000. A study of AroP-PheP chimeric proteins and identification of a residue involved in tryptophan transport. J. Bacteriol. 182:2207-2217.
2. Hu, L. A., and S. C. King. 1998. Functional sensitivity of polar surfaces on transmembrane helix 8 and cytoplasmic loop 8-9 of the Escherichia coli GABA (4-aminobutyrate) transporter encoded by gabP: mutagenic analysis of a consensus amphipathic region found in transporters from bacteria to mammals. Biochem. J. 330:771-776.
3. Hu, L. A., and S. C. King. 1998. Membrane topology of the Escherichia coli gamma-aminobutyrate transporter: implications on the topography and mechanism of prokaryotic transporters from the APC superfamily. Biochem J. 336:69-76.
4. Metzer, E., and Y. S. Halpern. 1990. In vivo cloning and characterization of gabCTDP gene cluster of Escherichia coli K-12. J. Bacteriol. 172:3250-3256.
5. Monod, J., G. Cohen-Bazire, and M. Cohn. 1951. Sur la biosynthese de la β-galactosidase (lactase) chez Escherichia coli. La specificite de l'induction. Biochim. Biophys. Acta 7:585-599.
6. Pi, J., C. Dogovski, and A. J. Pittard. 1998. Functional consequences of changing proline residues in the phenylalanine-specific permease of Escherichia coli. J. Bacteriol. 180:5515-5519.
7. Pi, J., and A. J. Pittard. 1996. Topology of the phenylalanine-specific permease of Escherichia coli. J. Bacteriol. 178:2650-2655.
8. Pi, J., P. J. Wookey, and A. J. Pittard. 1991. Cloning and sequencing of the pheP gene, which encodes the phenylalanine-specific transport system of Escherichia coli. J. Bacteriol. 173:3622-3629.
9. Pi, J., P. J. Wookey, and A. J. Pittard. 1993. Site-directed mutagenesis reveals the importance of conserved charged residues for the transport activity of the PheP permease of Escherichia coli. J. Bacteriol. 175:7500-7504.
10. Pouwels, P. H., B. E. Enger-Valk, and W. J. Brammar. 1985. Cloning vectors, p. I-A-ii-1. Elsevier Science Publishers, B. V., Amsterdam, The Netherlands.
11. Sahin-Toth, M., and H. R. Kaback. 1993. Properties of interacting aspartic acid and lysine residues in the lactose permease of Escherichia coli. Biochemistry 32:10027-10035.
12. Slotboom, D. J., I. Sobczak, W. N. Konings, and J. S. Lolkema. 1999. A conserved serine-rich stretch in the glutamate transporter family forms a substrate-sensitive reentrant loop. Proc. Natl. Acad. Sci. USA 96:14282-14287.
13. Vandeyar, M. A., M. P. Weiner, C. J. Hutton, and C. A. Batt. 1988. A simple and rapid method for the selection of oligodeoxynucleotide-directed mutants. Gene 65:129-133.
14. Veenhoff, L. M., E. R. Geertsma, J. Knol, and B. Poolman. 2000. Close approximation of putative alpha-helices II, IV, VII, X, and XI in the translocation pathway of the lactose transport protein of Streptococcus thermophilus. J. Biol. Chem. 275:23834-23840.
15. Young, G. B., D. L. Jack, D. W. Smith, and M. H. Saier, Jr. 1999. The amino acid/auxin:proton symport permease family. Biochim. Biophys. Acta 1415:306-322.