Different distribution of nitric oxide synthase and soluble guanylyl cyclase activities in the detrusor and proximal urethra of the rabbit

Journal of Urology

Volumn 168, Issue 5, 2002, Pages 2286-2290

  Masuda, Hitoshi ^a   Okuno, Tetsuo ^a   Suzuki, Masahito ^a   Kihara, Kazunori ^a   Goto, Moritaka ^a   Azuma, Hiroshi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Bladder; Electric stimulation; Nitric oxide synthase; Rabbits; Urethra

Indexed keywords

8 BROMO CYCLIC GMP; GUANYLATE CYCLASE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DETRUSOR MUSCLE; ELECTROSTIMULATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME LOCALIZATION; EXCISION; MALE; MUCOSA; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE RELAXATION; URETHRA;

EID: 0036837648     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)64372-8     Document Type: Article

References (25)

1. Ehrén, I., Iversen, H., Jansson, O., Adolfsson, J. and Wiklund, N. P.: Localization of nitric oxide synthase activity in the human lower urinary tract and its correlation with neuroef-fector responses. Urology, 44: 683, 1994
2. Persson, K., Alm, P., Johansson, K., Larsson, B. and Andersson, K. E.: Nitric oxide synthase in pig lower urinary tract: immunohistochemistry, NADPH diaphorase histochemistry and functional effects. Br J Pharmacol, 110: 521, 1993
3. Triguero, D., Prietro, D. and Garcia-Pascual, A.: NADPH-diaphorase and NANC relaxations are correlated in the sheep urinary tract. Neurosci Lett, 163: 93, 1993
4. Masuda, H., Tsujii, T., Okuno, T., Kihara, K., Goto, M. and Azuma, H.: Localization and role of nitric oxide synthase and endogenous nitric oxide synthase inhibitors in the rabbit lower urinary tract. J Urol, 167: 2235, 2002
5. Jung, H. C., Mun, K. H., Park, T. C., Lee, Y. C., Park, J. M., Huh, K. et al: Role of nitric oxide in penile erection. Yonsei Med J, 38: 261, 1997
6. Persson, K., Igawa, Y., Mattiasson, A. and Andersson, K. E.: Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro. Br J Pharmacol, 107: 178, 1992
7. Ehrén, I., Hammarström, J., Adolfsson, J. and Wiklund, N. P.: Induction of calcium-dependent nitric oxide synthase by sex hormones in the guinea-pig urinary bladder. Acta Physiol Scand, 153: 393, 1995
8. Burnett, A. L., Calvin, D. C., Chamness, S. L., Liu, J. X., Nelson, R. J., Klein, S. L. et al: Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase model idiopathic voiding disorders in humans. Nat Med, 3: 571, 1997
9. Fathian-Sabet, B., Bloch, W., Klotz, T., Niggemann, S., Jacobs, G., Addicks, K. et al: Localization of constitutive nitric oxide synthase isoforms and the nitric oxide target enzyme soluble guanylyl cyclase in the human bladder. J Urol, 165: 1724, 2001
10. Birder, L. A., Apodoca, G., de Groat, W. C. and Kanai, A. J.: Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder. Am J Physiol, 275: F226, 1998
11. Zygmunt, P. M., Zygmunt, P. K., Högestätt, E. D. and Andersson, K. E.: Effects of omega-conotoxin on adrenergic, cholinergic and NANC neurotransmission in the rabbit urethra and detrusor. Br J Pharmacol, 110: 1285, 1993
12. Mayer, B.: Regulation of nitric oxide synthase and soluble guanylyl cyclase. Cell Biochem Funct, 12: 167, 1994
13. Smet, P. J., Jonavicius, J., Marshall, V. R. and de Vente, J.: Distribution of nitric oxide synthase-immunoreactive nerves and identification of cellular targets of nitric oxide in guineapig and human urinary bladder by cGMP immunohistochemistry. Neuroscience, 71: 337, 1996
14. Levin, R. M., Hypolite, J. A., Haugard, N. and Wein, A. J.: Comparative response of rabbit bladder smooth muscle and mucosa to anoxia. Neurourol Urodyn, 15: 79, 1996
15. Wheeler, M. A., Pontari, M., Dokita, S., Nishimoto, T., Cho, Y. H., Hong, K. W. et al: Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle. Mol Cell Biochem, 169: 115, 1997
16. Doherty, P. C., Bivalacqua, T. J., Champion, H. C., Kadowitz, P., Greenwood-van Meerveld, B., Berzetei-Gurske, I. et al: Direct effects of selective type 5 phosphodiesterase inhibitors alone or with other vasodilators on the erectile response in cats. J Urol, 165: 1004, 2001
17. Moro, M. A., Russel, R. J., Cellek, S., Lizasoain, I., Su, Y., Darley-Usmar, V. M. et al: C-GMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase. Proc Natl Acad Sci USA, 93: 1480, 1996
18. Pinna, C., Ventura, S., Puglisi, L. and Burnstock, G.: A pharmacological and histochemical study of hamster urethra and the role of urothelium. Br J Pharmacol, 119: 655, 1996
19. Persson, K. and Andersson, K.-E.: Nitric oxide and relaxation of pig lower urinary tract. Br J Pharmacol, 106: 416, 1992
20. Jansson, O. T., Morcos, E., Brundin, L., Lundberg, J. O., Adolfsson, J., Soderhall, M. et al: The role of nitric oxide in bacillus Calmette-Guerin mediated anti-tumour effects in human bladder cancer. Br J Cancer, 78: 588, 1998
21. Pandita, R. K., Mizusawa, H. and Andersson, K.-E.: Intravesical oxyhemoglobin initiates bladder overactivity in conscious, normal rats. J Urol, 164: 545, 2000
22. Persson, K., Pandita, R. K., Asódi, A., Fässler, R., Andersson, K.-E., Pfeifer, A. et al: The absence of cyclic GMP-dependent kinase I causes hyperactive voiding and impaired urethral relaxation. J Urol, suppl., 161: 40, abstract 143, 1999
23. Kakizaki, H. and de Groat, W. C.: Role of spinal nitric oxide in the facilitation of the micturition reflex by bladder irritation. J Urol, 155: 355, 1996
24. Vizzard, M. A., Erdman, S. L. and de Groat, W. C.: Increased expression of neuronal nitric oxide synthase (NOS) and Fos proteins in neural pathways following acute and chronic irritation of the urinary tract in rats. Abstracts Soc Neurosci, 21: 647, 1995
25. Olsson, L. E., Wheeler, M. A., Sessa, W. C. and Weiss, R. M.: Bladder instillation and intraperitoneal injection of Esherichia coli lipopolysaccharide up-regulate cytokines and iNOS in rat urinary bladder. J Pharmacol Exp Ther, 284: 1203, 1998