Collision-induced dissociation actualized the H+-promoted reaction as observed in vitro; harman formation from β-carboline-type monoterpenoid glucoindole alkaloids

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 11, 2002, Pages 1528-1529

  Aimi, Norio ^a   Kitajima, Mariko ^a   Yokoya, Masashi ^a   Takayama, Hiromitsu ^a   Sakamoto, Shigeru ^a   Yamaguchi, Kentaro ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

carboline alkaloid; CID; Fragmentation; Harman; Monoterpenoid glucoindole alkaloid; MS MS

Indexed keywords

BETA CARBOLINE; HARMAN; INDOLE DERIVATIVE; TERPENE DERIVATIVE; ALKALOID; CARBOLINE DERIVATIVE; DRUG DERIVATIVE; HARMINE; PROTON; TERPENE;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; IN VITRO STUDY; MASS SPECTROMETRY; SIGNAL TRANSDUCTION; CHEMISTRY; METABOLISM;

ALKALOIDS; CARBOLINES; HARMINE; INDOLES; MONOTERPENES; PROTONS;

EID: 0036833404     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1528     Document Type: Article

References (11)

1. Gröger D., "Biochemistry of Alkaloids," ed. by Mothes K., Schütte H. R., Luckner M., VCH, Berlin, 1985, pp. 275-277, and references cited therein.
2. Atta-ur-Rhaman, Basha A., "Biosynthesis of Indole Alkaloids," Claredon Press, Oxford, 1983, p. 156, and references cited therein.
3. Aimi N., Murakami H., Tuyuki T., Nishiyama T., Sakai S., Haginiwa J., Chem. Pharm. Bull., 34, 3064-3066 (1986).
4. Kitajima M., Hashimoto K., Yokoya M., Takayama H., Aimi N., Chem. Pharm. Bull., 48, 1410-1411 (2000).
5. Kitajima M., Yokoya M., Takayama H., Aimi N., Nat. Med., 55, 308-310 (2001).
6. Hoffman E. D., Charette J., Stroobant V., "Mass Spectrometry; Principles and Applications," John Wiley, New York, 1996.
7. Cooks R. G., Wong P. S. H., Acc. Chem. Res., 31, 379-386 (1998).
8. Busch K. L., Glish G. L., McLuckey S. A., "Mass Spectrometry/Mass Spectrometry: Techniques and Applications of Tandem Mass Spectrometry," VCH, New York, 1998.
9. +, 553, 423, 391, 240, 180.
10. 3OD) δ: 169.5 (16-COOMe), 168.1 (5-COOMe), 154.2 (C-17), 146.0 (C-3), 142.6 (C-13), 138.2 (C-5), 137.3 (C-2), 135.6 (C-19), 129.8 (C-8), 129.4 (C-11), 123.0 (C-9), 122.6 (C-7), 121.6 (C-10), 119.3 (C-18), 117.3 (C-6), 113.3 (C-12), 111.0 (C-16), 100.2 (C-1′), 97.4 (C-21), 52.8 (5-COOMe), 51.6 (16-COOMe).
11. Brown R. T., Duckworth D. M., Santos C. A. M., Tetrahedron Lett., 32, 1987-1990 (1991).