Loss of heterozygosity and mutations are the major mechanisms of RB1 gene inactivation in Chinese with sporadic retinoblastoma.

Human mutation

Volumn 20, Issue 5, 2002, Pages 408-

  Choy, Kwong Wai ^a   Pang, Chi Pui ^a   Yu, Christopher B O ^a   Wong, Hing Lok ^a   Ng, Joan S K ^a   Fan, Dorothy S P ^a   Lo, Kwok Wai ^a   Chai, Joshua T Y ^a   Wang, Jianhua ^a   Fu, Weiling ^a   Lam, Dennis S C ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOBLASTOMA PROTEIN;

ARTICLE; CASE REPORT; CELL CULTURE; CHINA; CHROMOSOME 13; CPG ISLAND; DNA METHYLATION; FEMALE; GENE SILENCING; GENETICS; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFANT; MALE; METABOLISM; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PROMOTER REGION; RETINA TUMOR; RETINOBLASTOMA; TUMOR SUPPRESSOR GENE;

CHILD, PRESCHOOL; CHINA; CHROMOSOMES, HUMAN, PAIR 13; CPG ISLANDS; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; FEMALE; GENE SILENCING; GENES, RETINOBLASTOMA; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MUTATION; PROMOTER REGIONS (GENETICS); RETINAL NEOPLASMS; RETINOBLASTOMA; RETINOBLASTOMA PROTEIN; TUMOR CELLS, CULTURED;

EID: 0036832410     PISSN: None     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.9077     Document Type: Article

References (0)