Practical protocols for stepwise solid-phase synthesis of cysteine-containing peptides

Journal of Peptide Research

Volumn 60, Issue 5, 2002, Pages 292-299

  Angell, Y M ^a,b   Alsina, J ^a,c   Barany, G ^a   Albericio, F ^d  

^a University of Minnesota   (United States)

^b PFIZER INC   (United States)

^c INDIANA UNIVERSITY   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Automated solid phase peptide synthesis; Cysteine; Hindered bases; Oxytocin; Racemization

Indexed keywords

(BENZOTRIAZOL 1 YL N OXY) TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; 1 HYDROXYBENZOTRIAZOLE; 2,3,5,6 TETRAMETHYLPYRIDINE; 2,6 DI TERT BUTYL 4 (DIMETHYLAMINO)PYRIDINE; 2,6 DIMETHYLPYRIDINE; 4 METHYLMORPHOLINE; APROTININ; BASE; COLLIDINE; CYSTEINE; DIHYDROOXYTOCIN; ETHYLAMINE; ETHYLDIISOPROPYLAMINE; N [(DIMETHYLAMINO) 1H 1,2,3 TRIAZOLO[4,5 B]PYRIDIN 1 YLMETHYLENE] N METHYLMETHANAMINIUM HEXAFLUOROPHOSPHATE N OXIDE; N [1H BENZOTRIAZOL 1 YL (DIMETHYLAMINO)METHYLENE] N METHYLMETHANAMINIUM HEXAFLUOROPHOSPHATE N OXIDE; N,N' DIISOPROPYLCARBOIIMIDE; NONAPEPTIDE; O PENTAFLUOROPHENYL ESTER; OCTAHYDROACRIDINE; PEPTIDE DERIVATIVE; PHOSPHATE; TRIPEPTIDE; UNCLASSIFIED DRUG; PEPTIDE;

ARTICLE; AUTOMATION; CHEMICAL REACTION; MOLECULAR MODEL; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; SOLID; STEREOISOMERISM; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SYNTHESIS;

BOVINAE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; PEPTIDES;

EID: 0036830576     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.02838.x     Document Type: Article

References (14)

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2. Angell, Y.M., Han, Y., Albericio, F. & Barany, G. (1999) Minimization of cysteine racemization during stepwise solid-phase peptide synthesis. In Innovations and Perspectives in Solid Phase Synthesis and Combinatorial Libraries, 1998 (Epton, R., ed.). Mayflower Scientific, Kingswinford, UK, pp. 247-248.
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