H-NMR assay of papaverine hydrochloride and formulations

Phytochemical Analysis

Volumn 13, Issue 6, 2002, Pages 301-304

  Aboutabl, Elsayed A ^a   El Azzouny, Aida A ^b   Afifi, Manal S ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Assay of injections; Assay of tablets; Papaverine hydrochloride; Pronto NMR; Quantitative assay

Indexed keywords

DRUG DOSAGE;

ASSAY OF INJECTION; ASSAY OF TABLET; BULK DRUGS; DOSAGE FORMS; INTERNAL STANDARDS; METHOXY GROUP; PAPAVERINE HYDROCHLORIDE; PRONTO NMR; QUANTITATIVE ASSAY; QUANTITATIVE DETERMINATIONS;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACETANILIDE; ALKALOID; PAPAVERINE; PROTON; ACETANILIDE DERIVATIVE;

ACCURACY; AMPOULE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG IDENTIFICATION; DRUG PURITY; DRUG STRUCTURE; INJECTION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; STANDARD; TABLET FORMULATION; CHEMISTRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PAPAVER; TABLET;

ACETANILIDES; DOSAGE FORMS; MAGNETIC RESONANCE SPECTROSCOPY; PAPAVER; PAPAVERINE; PROTONS; TABLETS;

EID: 0036826997     PISSN: 09580344     EISSN: None     Source Type: Journal    
DOI: 10.1002/pca.657     Document Type: Article

References (19)

1. Abounassif MA, Abdel-Moety EM, Gad-Kariem EA. 1990. HPLC quantification of azintamide and papaverine hydrochloride simultaneously in pharmaceutical preparations. J Liq Chromatogr 13: 2689-2698.
2. Drozhzhina VV. 1978. Spectrophoto metric determination of papaverine hydrochloride in suppositories. Farmatsiya 27: 82-83.
3. Egyptian Pharmacopoeia. 1984. 3rd edn. Ministry of Health, General Organization for Government Printing Office: Cairo.
4. Elks E, Ganellin CR. 1990. Dictionary of Drugs: Chemical Data, Structures and Bibliographies. Chapman and Hall: London; 931.
5. Eppelsheim C, Aubeck R, Hampp N, Brauchle C. 1991. Determination of etaverine and papaverine using ion selective electrodes. Analyst 116: 1001-1003.
6. Kleemann A, Engel J. 1999. Pharmaceutical Substances. Thieme: Stuttgart; 1443-1444.
7. Kreighbaum WE, Kavanaugh WF, Comer WT, Deitchman D. 1972. 3(2H)-Isoquinolones. 1,3-Oxygenated analogues of papaverine as peripheral vasodilators. J Med Chem 15:1131-1135.
8. Manske RHF. 1954. The Alkaloids, Vol. 4. Academic Press: London; 29.
9. Maurich V, Moneghini M. 1983. HPLC separation of papaverine hydrochloride and its degradation products papaveraldine and papaverinol. Quantitative determination in vials and granules. Bull Chim Farm 122: 322-329.
10. Moussa AF. 1978. Spectrophotometric determination of papaverine in some pharmaceutical preparations containing noramidopyrine methansulphonate sodium. Pharmazie 33: 460-461.
11. Ono M, Shimamine M, Takahashi K. 1971. The application of non-aqueous titration procedure to medicinal narcotic drugs 3. Determination of papaverine hydrochloride in opium alkaloid hydrochlorides, atropine and papaverine injection. Bull Nat Inst Hyg Sci 89: 81-82.
12. Pauli GF. 2001. A versatile concept for the validation of natural product reference compounds. Phytochem Anal 12: 28-42.
13. Reynolds JEF. 1996. Martindale: the Extra Pharmacopoeia, 3rd edn. Pharmaceutical Press: London.
14. Shoukry A, Issa YM, Ibrahim H, El-Rashiedy OA. 1991. Papaverine-selective plastic membrane electrode based on papaverinium tetraphenylborate. Anal Lett 24: 1861-1873.
15. United States Pharmacopoeia. 1995. USP 23 National Formulary 18. United States Pharmacopoeial Convention: Rockville.
16. Valka I, Walterova D, Simanek V. 1985. Determination of papaverine by capillary isotachophoresis. J Chromatogr 350: 336-338.
17. Wagner H, Bladt S, Zgainski EM. 1983. Drogenanalyse. Springer: Berlin.
18. Zavrazhnaya TA, Kuleshova MI. 1982. Determination of papaverine hydrochloride and ethyl morphine hydrochloride in medicinal preparations by gas chromatography. Farmatsiya 31: 32-34.
19. Zhebentajaev AI. 1988. Spectrophotometric determination of papaverine hydrochloride by reaction with phloxin. Chem Nat Comp 6: 712-714.